Výsledky vyhledávání - "Ewelina, Stoczyńska"

The Genetic Diversity of Proteasome Genes in the T1DM Polish Population

Autor: Tomasz Wasiak, Tadeusz Strózik, Krystyna Jędrychowska-Dańska, Alicja Zamerska, Ewelina Stoczyńska-Fidelus

Publikováno v: Current Diabetes Reviews. 19

Background: Autoimmune metabolic diseases generate numerous healthy and social problems. The possible association of SNPs in the ubiquitin-proteasome system (UPS) with human pathology is under intensive study. Objective: In the present study, the gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5928b0a70577c1631dbeb65309d10eb2
https://doi.org/10.2174/1573399819666221214111800

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Phenotypical Flexibility of the EGFRvIII-Positive Glioblastoma Cell Line and the Multidirectional Influence of TGFβ and EGF on These Cells-EGFRvIII Appears as a Weak Oncogene

Autor: Aneta Włodarczyk, Cezary Tręda, Adrianna Rutkowska, Dagmara Grot, Weronika Dobrewa, Amelia Kierasińska, Marta Węgierska, Tomasz Wasiak, Tadeusz Strózik, Piotr Rieske, Ewelina Stoczyńska-Fidelus

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 20; Pages: 12129

Background: The biological role of EGFRvIII (epidermal growth factor receptor variant three) remains unclear. Methods: Three glioblastoma DK-MG sublines were tested with EGF (epidermal growth factor) and TGFβ (transforming growth factor β). Subline

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00fb8f5607f87d7265d3dc99a76e10e2
https://pubmed.ncbi.nlm.nih.gov/36292985

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Increased EGFRvIII Epitope Accessibility after Tyrosine Kinase Inhibitor Treatment of Glioblastoma Cells Creates More Opportunities for Immunotherapy

Autor: Cezary Tręda, Aneta Włodarczyk, Marcin Pacholczyk, Adrianna Rutkowska, Ewelina Stoczyńska-Fidelus, Amelia Kierasińska, Piotr Rieske

Publikováno v: International Journal of Molecular Sciences
Volume 24
Issue 5
Pages: 4350

The number of glioblastoma (GB) cases is increasing every year, and the currently available therapies remain ineffective. A prospective antigen for GB therapy is EGFRvIII, an EGFR deletion mutant containing a unique epitope that is recognized by the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98fc14c4b9f6389751ad990b93f9502c
https://doi.org/10.3390/ijms24054350

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Akademický článek

Screening for EGFR amplifications with a novel method and their significance for the outcome of glioblastoma patients.

Autor: Michał Bieńkowski, Sylwester Piaskowski, Ewelina Stoczyńska-Fidelus, Małgorzata Szybka, Mateusz Banaszczyk, Monika Witusik-Perkowska, Emilia Jesień-Lewandowicz, Dariusz J Jaskólski, Anna Radomiak-Załuska, Dorota Jesionek-Kupnicka, Beata Sikorska, Wielisław Papierz, Piotr Rieske, Paweł P Liberski

Publikováno v: PLoS ONE, Vol 8, Iss 6, p e65444 (2013)

Glioblastoma is a highly aggressive tumour of the central nervous system, characterised by poor prognosis irrespective of the applied treatment. The aim of our study was to analyse whether the molecular markers of glioblastoma (i.e. TP53 and IDH1 mut

Externí odkaz: https://doaj.org/article/4701ffcbbfd744298db6f7d4fb280757

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BCR/ABL Stimulates WRN to Promote Survival and Genomic Instability

Autor: Dariusz Pytel, Tomasz Poplawski, Michał Nowicki, Tomasz Skorski, Kimberly Cramer, Artur Slupianek, Ewelina Stoczyńska, Stanislaw K. Jozwiakowski, Janusz Blasiak

Publikováno v: Cancer Research. 71:842-851

BCR/ABL-transformed chronic myeloid leukemia (CML) cells accumulate numerous DNA double-strand breaks (DSB) induced by reactive oxygen species (ROS) and genotoxic agents. To repair these lesions BCR/ABL stimulate unfaithful DSB repair pathways, homol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6db737165df77ff09471a58315a103fa
https://doi.org/10.1158/0008-5472.can-10-1066

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[Role of oxidative mechanisms in the pathogenesis of age-related macular degeneration]

Autor: Katarzyna, Janik-Papis, Magdalena, Ulińska, Anna, Krzyzanowska, Ewelina, Stoczyńska, Anna I, Borucka, Katarzyna, Woźniak, Zaras, Małgorzata, Jacek P, Szaflik, Janusz, Blasiak

Publikováno v: Klinika oczna. 111(4-6)

Oxidative stress is a major factor in the pathogenesis of age-related macular degeneration (AMD). Retinal pigment epithelial (RPE) cells are prone to reactive oxygen species (ROS) arising during the stress due to intense oxygen metabolism and a high

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::31fceae12b115e18832af7b65e8721c0
https://pubmed.ncbi.nlm.nih.gov/19673452

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[Non-homologous DNA end joining--new proteins, new functions, new mechanisms]

Autor: Tomasz, Popławski, Ewelina, Stoczyńska, Janusz, Błasiak

Publikováno v: Postepy biochemii. 55(1)

Humans use primarily nonhomologous end joining (NHEJ) to repair DNA double strand breaks (DSBs), which are the most serious DNA damage, resulting in cell death if non-repaired or missrepaired. NHEJ directly joins together DNA ends resulted from DSBs.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::88610d20d7e84d1329c4e9a456ef3b16
https://pubmed.ncbi.nlm.nih.gov/19514464

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