Zobrazeno 1 - 10
of 493
pro vyhledávání: '"Ewart W"'
Autor:
Sebastiaan van Heesch, Marieke Simonis, Markus J. van Roosmalen, Vamsee Pillalamarri, Harrison Brand, Ewart W. Kuijk, Kim L. de Luca, Nico Lansu, A. Koen Braat, Androniki Menelaou, Wensi Hao, Jeroen Korving, Simone Snijder, Lars T. van der Veken, Ron Hochstenbach, Alida C. Knegt, Karen Duran, Ivo Renkens, Najla Alekozai, Myrthe Jager, Sarah Vergult, Björn Menten, Ewart de Bruijn, Sander Boymans, Elly Ippel, Ellen van Binsbergen, Michael E. Talkowski, Klaske Lichtenbelt, Edwin Cuppen, Wigard P. Kloosterman
Publikováno v:
Cell Reports, Vol 9, Iss 6, Pp 2001-2010 (2014)
Genomic rearrangements are a common cause of human congenital abnormalities. However, their origin and consequences are poorly understood. We performed molecular analysis of two patients with congenital disease who carried de novo genomic rearrangeme
Externí odkaz:
https://doaj.org/article/3fde279ae3264a15b1b84b25ba00f8e2
Autor:
Gijs Teklenburg, Charlotte H E Weimar, Bart C J M Fauser, Nick Macklon, Niels Geijsen, Cobi J Heijnen, Susana M Chuva de Sousa Lopes, Ewart W Kuijk
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32701 (2012)
Female mammals inactivate one of their two X-chromosomes to compensate for the difference in gene-dosage with males that have just one X-chromosome. X-chromosome inactivation is initiated by the expression of the non-coding RNA Xist, which coats the
Externí odkaz:
https://doaj.org/article/0ad0cfa30b7a42f4a6e3dfb568287ca1
Autor:
Ewart W Kuijk, Jeffrey de Gier, Susana M Chuva de Sousa Lopes, Ian Chambers, Ans M M van Pelt, Ben Colenbrander, Bernard A J Roelen
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e10987 (2010)
NANOG is a key player in pluripotency and its expression is restricted to pluripotent cells of the inner cell mass, the epiblast and to primordial germ cells. Spermatogenesis is closely associated with pluripotency, because through this process highl
Externí odkaz:
https://doaj.org/article/bf2b995601c643e592957276c173c077
Autor:
Gijs Teklenburg, Madhuri Salker, Mariam Molokhia, Stuart Lavery, Geoffrey Trew, Tepchongchit Aojanepong, Helen J Mardon, Amali U Lokugamage, Raj Rai, Christian Landles, Bernard A J Roelen, Siobhan Quenby, Ewart W Kuijk, Annemieke Kavelaars, Cobi J Heijnen, Lesley Regan, Jan J Brosens, Nick S Macklon
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10258 (2010)
Pregnancy is widely viewed as dependent upon an intimate dialogue, mediated by locally secreted factors between a developmentally competent embryo and a receptive endometrium. Reproductive success in humans is however limited, largely because of the
Externí odkaz:
https://doaj.org/article/b5367540c86a41c39c1b7169889fd6c0
Autor:
Madhuri Salker, Gijs Teklenburg, Mariam Molokhia, Stuart Lavery, Geoffrey Trew, Tepchongchit Aojanepong, Helen J Mardon, Amali U Lokugamage, Raj Rai, Christian Landles, Bernard A J Roelen, Siobhan Quenby, Ewart W Kuijk, Annemieke Kavelaars, Cobi J Heijnen, Lesley Regan, Nick S Macklon, Jan J Brosens
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10287 (2010)
Recurrent pregnancy loss (RPL), defined as 3 or more consecutive miscarriages, is widely attributed either to repeated chromosomal instability in the conceptus or to uterine factors that are poorly defined. We tested the hypothesis that abnormal cycl
Externí odkaz:
https://doaj.org/article/561f04d2ecfb485aa97a0e4a309e75a4
Autor:
Infantino, Angelo, Blackmore, Ewart W., Brugger, Markus, Alía, Rubén García, Stukel, Matthew, Trinczek, Michael
Publikováno v:
In Nuclear Inst. and Methods in Physics Research, A 1 December 2016 838:109-116
Autor:
Ruben van Boxtel, Nicolle Besselink, Mauro D. Locati, Sander Boymans, Ruby Lieshout, Roel Janssen, Luan Nguyen, Michail Doukas, Myrthe Jager, Ewart W. Kuijk, Edwin Cuppen, Luc J. W. van der Laan, Jeroen de Jonge, Bastiaan van der Roest, Jan N. M. IJzermans, Petra E. de Ruiter, Monique M A Verstegen
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
Communications Biology, 4(1):1301. Springer Nature
Communications Biology
Communications Biology, 4(1):1301. Springer Nature
Communications Biology
Inflammatory liver disease increases the risk of developing primary liver cancer. The mechanism through which liver disease induces tumorigenesis remains unclear, but is thought to occur via increased mutagenesis. Here, we performed whole-genome sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a43ac1047b60b049f8ee5bc74e77e882
https://doaj.org/article/96839cce3bec43feb376e5547a803268
https://doaj.org/article/96839cce3bec43feb376e5547a803268
Autor:
Camille Bélanger-Champagne, Cornelia Hoehr, Ewart W. Blackmore, Clayton Lindsay, Michael Trinczek
Publikováno v:
IEEE Transactions on Nuclear Science. 67:161-168
During single-event effect (SEE) testing of electronic devices with collimated proton and neutron beams at accelerator facilities, support equipment is often located in close proximity to the beam. Background radiation in the area outside the nominal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b3f6b3f96c9229f3a35c7d6ad578c49
https://doi.org/10.1109/tns.2019.2952003
https://doi.org/10.1109/tns.2019.2952003
Autor:
Arne Van Hoeck, Ewart W. Kuijk, Bastiaan van der Roest, Sharon Christensen, Edwin Cuppen, John W.M. Martens, Peter Priestley, Sander Boymans, Marie-Laure Yaspo, Roel Janssen, Nicolle Besselink
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Nature Communications, 10(1). Nature Publishing Group
Nature Communications, 10:4571. Nature Publishing Group
Nature Communications
Nature Communications, 10(1). Nature Publishing Group
Nature Communications, 10:4571. Nature Publishing Group
5-Fluorouracil (5-FU) is a chemotherapeutic drug commonly used for the treatment of solid cancers. It is proposed that 5-FU interferes with nucleotide synthesis and incorporates into DNA, which may have a mutational impact on both surviving tumor and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d022daea376e11d88678275cc1b6daa
https://doaj.org/article/367df1c239a3400ab814acaa85f4ccbc
https://doaj.org/article/367df1c239a3400ab814acaa85f4ccbc
Autor:
Camille Bélanger-Champagne, Philippe Paillet, Cosimo Campanella, Cornelia Hoehr, Julien Mekki, Sylvain Girard, Jeoffray Vidalot, Michael Trinczek, Aziz Boukenter, Ewart W. Blackmore, Youcef Ouerdane, Gaetano Li Vecchi, N. Balcon, Adriana Morana, Damien Lambert, Emmanuel Marin
Publikováno v:
Sensors
Sensors, 2020, 20 (16), pp.4510. ⟨10.3390/s20164510⟩
Sensors (Basel, Switzerland)
Sensors, MDPI, 2020, 20 (16), pp.4510. ⟨10.3390/s20164510⟩
Sensors, Vol 20, Iss 4510, p 4510 (2020)
Sensors, 2020, 20 (16), pp.4510. ⟨10.3390/s20164510⟩
Sensors (Basel, Switzerland)
Sensors, MDPI, 2020, 20 (16), pp.4510. ⟨10.3390/s20164510⟩
Sensors, Vol 20, Iss 4510, p 4510 (2020)
The potential of fiber-based sensors to monitor the fluence of atmospheric neutrons is evaluated through accelerated tests at the TRIUMF Neutron Facility (TNF) (BC, Canada), offering a flux approximatively 109 higher than the reference spectrum obser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bebad7f98fd9eb4e5bfdb014643559c
https://ujm.hal.science/ujm-03271916
https://ujm.hal.science/ujm-03271916
