Exploring the effect of human and animal population growth on vector-borne disease transmission with an agent-based model of Rhodesian human African trypanosomiasis in eastern province, Zambia.

Autor: Simon Alderton, Ewan T Macleod, Neil E Anderson, Noreen Machila, Martin Simuunza, Susan C Welburn, Peter M Atkinson

Publikováno v: PLoS Neglected Tropical Diseases, Vol 12, Iss 11, p e0006905 (2018)

This paper presents the development of an agent-based model (ABM) to investigate Trypanosoma brucei rhodesiense human African trypanosomiasis (rHAT) disease transmission. The ABM model, fitted at a fine spatial scale, was used to explore the impact o

Externí odkaz: https://doaj.org/article/2335ffd40c17459caea4959e52302f54

Sodalis glossinidius prevalence and trypanosome presence in tsetse from Luambe National Park, Zambia

Autor: Jonny W Dennis, Simon M Durkin, Jemima E Horsley Downie, Louise C Hamill, Neil E Anderson, Ewan T MacLeod

Publikováno v: Parasites & Vectors, Vol 7, Iss 1, Pp 1-11 (2014)

Abstract Background Tsetse flies are the biological vectors of African trypanosomes, the causative agents of sleeping sickness in humans and nagana in animals. The tsetse endosymbiont Sodalis glossinidius has been suggested to play a role in tsetse s

Externí odkaz: https://doaj.org/article/81167a6af5f445ac9f072c743e41176e

Development of real time PCR to study experimental mixed infections of T. congolense Savannah and T. b. brucei in Glossina morsitans morsitans.

Autor: Heba A Ahmed, Ewan T MacLeod, Susan C Welburn, Kim Picozzi

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0117147 (2015)

Tsetse flies are able to acquire mixed infections naturally or experimentally either simultaneously or sequentially. Traditionally, natural infection rates in tsetse flies are estimated by microscopic examination of different parts of the fly after d

Externí odkaz: https://doaj.org/article/830d9ff576734e85a25874b344964e24

Critical Linkages Between Livestock Production, Livestock Trade and Potential Spread of Human African Trypanosomiasis in Uganda: Bioeconomic Herd Modeling and Livestock Trade Analysis

Autor: Walter O. Okello, Ewan T. MacLeod, Dennis Muhanguzi, Charles Waiswa, Alexandra P. Shaw, Susan C. Welburn

Publikováno v: Okello, W, MacLeod, E T, Muhanguzi, D, Waiswa, C, Shaw, A P & Welburn, S C 2021, ' Critical linkages between livestock production, livestock trade and potential spread of human African trypanosomiasis in Uganda : Bioeconomic herd modeling and livestock trade analysis ', Frontiers in Veterinary Science, vol. 8, 611141 . https://doi.org/10.3389/fvets.2021.611141
Frontiers in Veterinary Science
Frontiers in Veterinary Science, Vol 8 (2021)

Background: Tsetse-transmitted human African trypanosomiasis (HAT) remains endemic in Uganda. The chronic form caused by Trypanosoma brucei gambiense (gHAT) is found in north-western Uganda, whereas the acute zoonotic form of the disease, caused by T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a10329345f28aa7d54c86565b91c65d
https://doi.org/10.3389/fvets.2021.611141

G418 induces programmed cell death in Acanthamoeba through the elevation of intracellular calcium and cytochrome c translocation

Autor: Zisis Koutsogiannis, Sutherland K. Maciver, Ewan T. MacLeod

Publikováno v: Koutsogiannis, Z, MacLeod, E & Maciver, S 2019, ' G418 induces programmed cell death in Acanthamoeba through the elevation of intracellular calcium and cytochrome c translocation ', Parasitology Research, vol. 118, no. 2, pp. 641–651 . https://doi.org/10.1007/s00436-018-6192-0
Parasitology Research

Acanthamoeba is a widely distributed opportunistic parasite which causes a vision-threatening keratitis and a life-threatening encephalitis. The cyst stage of this amoeba is especially resistant to currently used therapeutics and so alternative agent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01bed44401ec8f46cb08efe584369518
https://doi.org/10.1007/s00436-018-6192-0