Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Ewan R. Cameron"'
Publikováno v:
Cells, Vol 12, Iss 4, p 641 (2023)
Dissecting and identifying the major actors and pathways in the genesis, progression and aggressive advancement of breast cancer is challenging, in part because neoplasms arising in this tissue represent distinct diseases and in part because the tumo
Externí odkaz:
https://doaj.org/article/971f57fb9ef542789f475e0f97c6871a
Autor:
Laura McDonald, Nicola Ferrari, Anne Terry, Margaret Bell, Zahra M. Mohammed, Clare Orange, Alma Jenkins, William J. Muller, Barry A. Gusterson, James C. Neil, Joanne Edwards, Joanna S. Morris, Ewan R. Cameron, Karen Blyth
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 5, Pp 525-534 (2014)
RUNX2, a master regulator of osteogenesis, is oncogenic in the lymphoid lineage; however, little is known about its role in epithelial cancers. Upregulation of RUNX2 in cell lines correlates with increased invasiveness and the capacity to form osteol
Externí odkaz:
https://doaj.org/article/7f8cfc97bf4346f9a5ee800f466c956f
Autor:
Karen Blyth, Ewan R. Cameron, Joanne Edwards, Owen J. Sansom, Joshua D.G. Leach, William Clark, Colin Nixon, Dimitris Athineos, Steven Howard, Ann Hedley, Kirsteen J. Campbell, J. Henry M. Däbritz, Laura McDonald, Susan M. Mason, Nicholas Rooney
All Supplementary data figures and legends. Supplementary Figure 1. In Silico analysis of RUNX1 expression in human kidney cancer. Supplementary Figure 2. Knockdown of RUNX1 with shRNA causes a growth defect in two ccRCC cell lines. Supplementary Fig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f1cd5d76d642f2d71107273237d8e57
https://doi.org/10.1158/0008-5472.22423628
https://doi.org/10.1158/0008-5472.22423628
Autor:
Karen Blyth, Ewan R. Cameron, Joanne Edwards, Owen J. Sansom, Joshua D.G. Leach, William Clark, Colin Nixon, Dimitris Athineos, Steven Howard, Ann Hedley, Kirsteen J. Campbell, J. Henry M. Däbritz, Laura McDonald, Susan M. Mason, Nicholas Rooney
RNAseq data set
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af3afad67572d436fb44e2aeb5dd5d2
https://doi.org/10.1158/0008-5472.22423634.v1
https://doi.org/10.1158/0008-5472.22423634.v1
Autor:
Karen Blyth, Ewan R. Cameron, Joanne Edwards, Owen J. Sansom, Joshua D.G. Leach, William Clark, Colin Nixon, Dimitris Athineos, Steven Howard, Ann Hedley, Kirsteen J. Campbell, J. Henry M. Däbritz, Laura McDonald, Susan M. Mason, Nicholas Rooney
The recurring association of specific genetic lesions with particular types of cancer is a fascinating and largely unexplained area of cancer biology. This is particularly true of clear cell renal cell carcinoma (ccRCC) where, although key mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9b2c8fc44285f92b9bb2df21b6d2ad
https://doi.org/10.1158/0008-5472.c.6511538.v1
https://doi.org/10.1158/0008-5472.c.6511538.v1
Autor:
Karen Blyth, Ewan R. Cameron, Joanne Edwards, Owen J. Sansom, Joshua D.G. Leach, William Clark, Colin Nixon, Dimitris Athineos, Steven Howard, Ann Hedley, Kirsteen J. Campbell, J. Henry M. Däbritz, Laura McDonald, Susan M. Mason, Nicholas Rooney
Supplementary Table 1. The relationship between RUNX2 and clinico-pathological characteristics of kidney cancer in the TMA study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ccc08d2bbed38aad46b42df51d9ec63
https://doi.org/10.1158/0008-5472.22423625
https://doi.org/10.1158/0008-5472.22423625
Supplementary Figure 1 Legend from Runx Regulation of Sphingolipid Metabolism and Survival Signaling
Autor:
James C. Neil, Ewan R. Cameron, Michael J.O. Wakelam, Qifeng Zhang, Gillian Borland, Alma Jenkins, Anne Terry, Anna Kilbey
Supplementary Figure 1 Legend from Runx Regulation of Sphingolipid Metabolism and Survival Signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c642cc10c0b8ff0a03c84cda3f9d37d4
https://doi.org/10.1158/0008-5472.22381812
https://doi.org/10.1158/0008-5472.22381812
Autor:
James C. Neil, Ewan R. Cameron, Michael J.O. Wakelam, Qifeng Zhang, Gillian Borland, Alma Jenkins, Anne Terry, Anna Kilbey
Supplementary Figure 1 from Runx Regulation of Sphingolipid Metabolism and Survival Signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06884579edea7e0735421fea9fbac83e
https://doi.org/10.1158/0008-5472.22381809.v1
https://doi.org/10.1158/0008-5472.22381809.v1
Autor:
James C. Neil, Ewan R. Cameron, Michael J.O. Wakelam, Qifeng Zhang, Gillian Borland, Alma Jenkins, Anne Terry, Anna Kilbey
The Runx genes (Runx1, 2, and 3) regulate cell fate in development and can operate as either oncogenes or tumor suppressors in cancer. The oncogenic potential of ectopic Runx expression has been shown in transgenic mice that develop lymphoma in poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::877a880042d3afb682e5cf9670484174
https://doi.org/10.1158/0008-5472.c.6499986.v1
https://doi.org/10.1158/0008-5472.c.6499986.v1
Autor:
Stuart A. Nicklin, Christopher M. Loughrey, Ewan R. Cameron, Tamara P. Martin, Thomas Braun, Alexandra Riddell, Martin W. McBride
Publikováno v:
Cardiovascular Research
Runt-related transcription factor-1 (RUNX1), also known as acute myeloid leukaemia 1 protein (AML1), is a member of the core-binding factor family of transcription factors which modulate cell proliferation, differentiation, and survival in multiple s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4d58b07ae14743099227e06e4e592e
https://doi.org/10.1093/cvr/cvaa034
https://doi.org/10.1093/cvr/cvaa034