Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ewan R Taylor"'
Autor:
Michelle L Duquette, Qingyuan Zhu, Ewan R Taylor, Angela J Tsay, Linda Z Shi, Michael W Berns, Clare H McGowan
Publikováno v:
PLoS Genetics, Vol 8, Iss 11, p e1003050 (2012)
DNA interstrand crosslinks (ICLs) are toxic lesions that block the progression of replication and transcription. CtIP is a conserved DNA repair protein that facilitates DNA end resection in the double-strand break (DSB) repair pathway. Here we show t
Externí odkaz:
https://doaj.org/article/8f6f239b578c43518c801b93d319f176
Autor:
Samantha C. Faber, Tejas S. Lahoti, Ewan R. Taylor, Lauren Lewis, Jessica M. Sapiro, Vicencia Toledo Sales, Yvonne P. Dragan, Brandon D. Jeffy
Publikováno v:
Cells, Vol 11, Iss 10, p 1708 (2022)
Target modulation of the AhR for inflammatory gastrointestinal (GI) conditions holds great promise but also the potential for safety liabilities both within and beyond the GI tract. The ubiquitous expression of the AhR across mammalian tissues couple
Externí odkaz:
https://doaj.org/article/0303c4caed514b3cb378fbf7627fefee
Autor:
Mark Sabat, Douglas R Dougan, Beverly Knight, J. David Lawson, Nicholas Scorah, Christopher R Smith, Ewan R Taylor, Phong Vu, Corey Wyrick, Haixia Wang, Deepika Balakrishna, Mark Hixon, Loui Madakamutil, Donavon McConn
Publikováno v:
Journal of Medicinal Chemistry. 64:12893-12902
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3f8b9b1a52718a454e07ddda041d931
https://doi.org/10.1021/acs.jmedchem.1c01026
https://doi.org/10.1021/acs.jmedchem.1c01026
Autor:
Samira Fekairi, Sarah Scaglione, Charly Chahwan, Ewan R. Taylor, Agnès Tissier, Stéphane Coulon, Meng-Qiu Dong, Cristian Ruse, John R. Yates III, Paul Russell
Publikováno v:
Journal of End-to-End-testing. 138:78-89
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65ce6b8d5594a1a5d617ebd175f206ef
https://doi.org/10.1016/s9999-9994(09)20375-8
https://doi.org/10.1016/s9999-9994(09)20375-8
Autor:
Pierre-Henri L. Gaillard, Charly Chahwan, Ewan R. Taylor, Samira Fekairi, Stéphane Coulon, Paul Russell, Sarah Scaglione, Cristian I. Ruse, Clare H. McGowan, Agnès Tissier, John R. Yates, Meng-Qiu Dong, Robert P. P. Fuchs
Publikováno v:
Cell
Cell, Elsevier, 2009, 138 (1), pp.78-89. ⟨10.1016/j.cell.2009.06.029⟩
Cell, Elsevier, 2009, 138 (1), pp.78-89. ⟨10.1016/j.cell.2009.06.029⟩
SummaryStructure-specific endonucleases resolve DNA secondary structures generated during DNA repair and recombination. The yeast 5′ flap endonuclease Slx1-Slx4 has received particular attention with the finding that Slx4 has Slx1-independent key f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd3788d895410016acb59f7303bedc13
https://doi.org/10.1016/j.cell.2009.06.029
https://doi.org/10.1016/j.cell.2009.06.029
Autor:
Clare H. McGowan, Ewan R. Taylor
Publikováno v:
Proceedings of the National Academy of Sciences. 105:3757-3762
Recombination-mediated repair plays a central role in maintaining genomic integrity during DNA replication. The human Mus81–Eme1 endonuclease is involved in recombination repair, but the exact structures it acts on in vivo are not known. Using kine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26db609e769dc29a34b9232ba807a9ce
https://doi.org/10.1073/pnas.0710291105
https://doi.org/10.1073/pnas.0710291105
Autor:
Patricia Kannouche, Alan R. Lehmann, Winifred Boner, Julie A. Connolly, Edward S. Dornan, Shona McNair, Iain M. Morgan, Ewan R. Taylor
Publikováno v:
Journal of Biological Chemistry. 278:52223-52230
Human papillomaviruses (HPV) are causative agents in a variety of human diseases; for example over 99% of cervical carcinomas contain HPV DNA sequences. Often in cervical carcinoma the HPV genome is integrated into the host genome resulting in unregu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f27f53bdc60b04d3d362f82a228b63eb
https://doi.org/10.1074/jbc.m308779200
https://doi.org/10.1074/jbc.m308779200
Publikováno v:
Oncogene. 22:4469-4477
Human papillomaviruses (HPV) are causative agents of human cancers including those of the cervix and also of the head and neck; HPV16 is the most commonly found type in these diseases. The viral E2 protein regulates transcription from the viral genom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c288f6c0bb4389f64f0faca846725c8a
https://doi.org/10.1038/sj.onc.1206746
https://doi.org/10.1038/sj.onc.1206746
Autor:
Winifred Boner, M. Saveria Campo, Emmanouella Tsirimonaki, Iain M. Morgan, Kazuhiko Yamane, Ewan R. Taylor
Publikováno v:
Journal of Biological Chemistry. 277:22297-22303
The human papillomavirus (HPV) transcription/replication factor E2 is essential for the life cycle of HPVs. E2 protein binds to DNA target sequences in the viral long control regions to regulate transcription of the viral genome. It also enhances vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9123e80d28b8c588711be66207c264a
https://doi.org/10.1074/jbc.m202163200
https://doi.org/10.1074/jbc.m202163200
Autor:
Qingyuan Zhu, Ewan R. Taylor, Angela J. Tsay, Michael W. Berns, Linda Z. Shi, Michelle L. Duquette, Clare H. McGowan
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 8, Iss 11, p e1003050 (2012)
Duquette, Michelle L; Zhu, Qingyuan; Taylor, Ewan R; Tsay, Angela J; Shi, Linda Z; Berns, Michael W; et al.(2012). CtIP Is Required to Initiate Replication-Dependent Interstrand Crosslink Repair. PLoS Genetics, 8(11), e1003050. doi: 10.1371/journal.pgen.1003050. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/2283n21g
PLoS Genetics, Vol 8, Iss 11, p e1003050 (2012)
Duquette, Michelle L; Zhu, Qingyuan; Taylor, Ewan R; Tsay, Angela J; Shi, Linda Z; Berns, Michael W; et al.(2012). CtIP Is Required to Initiate Replication-Dependent Interstrand Crosslink Repair. PLoS Genetics, 8(11), e1003050. doi: 10.1371/journal.pgen.1003050. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/2283n21g
DNA interstrand crosslinks (ICLs) are toxic lesions that block the progression of replication and transcription. CtIP is a conserved DNA repair protein that facilitates DNA end resection in the double-strand break (DSB) repair pathway. Here we show t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f647d26caee1f2d7400c0b3423914b
https://pubmed.ncbi.nlm.nih.gov/23144634
https://pubmed.ncbi.nlm.nih.gov/23144634