Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ewan Millar"'
Autor:
Harvey W. Smith, Alison Hirukawa, Virginie Sanguin-Gendreau, Ipshita Nandi, Catherine R. Dufour, Dongmei Zuo, Kristofferson Tandoc, Matthew Leibovitch, Salendra Singh, Jonathan P. Rennhack, Matthew Swiatnicki, Cynthia Lavoie, Vasilios Papavasiliou, Carolin Temps, Neil O. Carragher, Asier Unciti-Broceta, Paul Savage, Mark Basik, Vincent van Hoef, Ola Larsson, Caroline L. Cooper, Ana Cristina Vargas Calderon, Jane Beith, Ewan Millar, Christina Selinger, Vincent Giguère, Morag Park, Lyndsay N. Harris, Vinay Varadan, Eran R. Andrechek, Sandra A. O’Toole, Ivan Topisirovic, William J. Muller
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Polycomb Repressor Complex 2 (PRC2) is frequently up-regulated in cancers. Here, the authors show that the tyrosine kinase c-Src stimulates mitochondrial function to signal energy sufficiency to mTORC1, increasing translation of the PRC2 subunits EZH
Externí odkaz:
https://doaj.org/article/4b4ac9959bb3404bb739e2634c53409f
Autor:
Timothy J. Molloy, Georgina E. Hollway, Harriet E. Gee, Francesca M. Buffa, Adrian L Harris, Sandra A. O’Toole, Joanne Toohey, Susan Carroll, Anaiis Zaratzian, Alice Boulghourjian, Charles E. de Bock, Angela Steinmann, Alison Drury, Peter H. Graham, Ewan Millar, Louise Doculara, Sheridan Daly, Danielle Froio, Marina Pajic
miR-139-5p overexpression significantly increased radiation sensitivity in 10 BC cell lines (A-I), and also sensitivity to ROS generator menadione (J).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af9f98530e31300fe125ac252f05b19
https://doi.org/10.1158/0008-5472.22417851
https://doi.org/10.1158/0008-5472.22417851
Autor:
Timothy J. Molloy, Georgina E. Hollway, Harriet E. Gee, Francesca M. Buffa, Adrian L Harris, Sandra A. O’Toole, Joanne Toohey, Susan Carroll, Anaiis Zaratzian, Alice Boulghourjian, Charles E. de Bock, Angela Steinmann, Alison Drury, Peter H. Graham, Ewan Millar, Louise Doculara, Sheridan Daly, Danielle Froio, Marina Pajic
Supplementary Tables 1-6 Supp. Table 1: Clinicopathological characteristics of breast cancer patients whose tumours were profiled by miRNA expression microarrays to identify miRNAs associated with local relapse following radiotherapy. Supp. Table 2:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f951d92c4452a370f5c128e23ffa4fa
https://doi.org/10.1158/0008-5472.22417845
https://doi.org/10.1158/0008-5472.22417845
Autor:
Timothy J. Molloy, Georgina E. Hollway, Harriet E. Gee, Francesca M. Buffa, Adrian L Harris, Sandra A. O’Toole, Joanne Toohey, Susan Carroll, Anaiis Zaratzian, Alice Boulghourjian, Charles E. de Bock, Angela Steinmann, Alison Drury, Peter H. Graham, Ewan Millar, Louise Doculara, Sheridan Daly, Danielle Froio, Marina Pajic
Radiotherapy is essential to the treatment of most solid tumors and acquired or innate resistance to this therapeutic modality is a major clinical problem. Here we show that miR-139-5p is a potent modulator of radiotherapy response in breast cancer v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c26eaaad942be250caced776fa8fee5
https://doi.org/10.1158/0008-5472.c.6509961
https://doi.org/10.1158/0008-5472.c.6509961
Autor:
Stephen B Fox, Fleur Webster, Chih‐Jung Chen, Boon Chua, Laura Collins, Maaria‐Pia Foschini, G Bruce Mann, Ewan Millar, Sarah E Pinder, Emad Rakha, Abeer Shaaban, Benjamin Y Tan, Gary Tse, Peter Watson, Puy Hoon Tan
Publikováno v:
HistopathologyReferences. 81(4)
To describe a new international dataset for pathology reporting of ductal carcinoma in situ (DCIS), variants of lobular carcinoma in situ (LCIS) and low-grade lesions (encapsulated papillary carcinoma, solid papillary carcinoma in situ, Paget's disea
Publikováno v:
Cancer Research. 83:PD9-01
Triple negative breast cancer (TNBC) is the most aggressive breast cancer subtype with poor prognosis and limited treatment options. One of the mechanisms contributing to this is the ability of TNBC tumors to evade anti-tumour response, limiting the
Autor:
Bill, Giannakopoulos, Peyman, Mirarabshahi, Miao, Qi, Chris, Weatherall, Jian Cheng, Qi, Kumiko, Tanaka, Ewan, Millar, Leon, Vonthethoff, Dominique, Gatto, Derek, Spielman, Steven A, Krilis
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 66(8)
The BXSB.Yaa mouse strain is a model of systemic lupus erythematosus that is dependent on duplication of the Toll-like receptor 7 gene. The objective of this study was to systematically describe the amplified autoimmune phenotype observed when the so
Autor:
Ewan Millar
Publikováno v:
The Breast. 10:263-265
Publikováno v:
Kidney international. 66(4)
Integrins have been implicated in the pathogenesis of a diverse range of kidney diseases. Herein, we provide the first detailed description of an epithelial restricted integrin, alpha(v)beta(6), in kidney biopsies from patients suffering acute and ch