Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ewan K. A. Millar"'
Autor:
Bridie S. Mulholland, Pierre Hofstee, Ewan K. A. Millar, Dana Bliuc, Sandra O'Toole, Mark R. Forwood, Michelle M. McDonald
Publikováno v:
Cancer Medicine, Vol 12, Iss 15, Pp 16221-16230 (2023)
Abstract Background Distant relapse of breast cancer complicates management of the disease and accounts for 90% of breast cancer‐related deaths. Monocyte chemoattractant protein‐1 (MCP‐1) has critical roles in breast cancer progression and is w
Externí odkaz:
https://doaj.org/article/b5a6711bc9124e4f84aba6d9490194c5
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Tumour heterogeneity in breast cancer poses challenges in predicting outcome and response to therapy. Spatial transcriptomics technologies may address these challenges, as they provide a wealth of information about gene expression at the cel
Externí odkaz:
https://doaj.org/article/23f7e7028ede4886bc5d51d54664e461
Autor:
Piumi Sandarenu, Ewan K. A. Millar, Yang Song, Lois Browne, Julia Beretov, Jodi Lynch, Peter H. Graham, Jitendra Jonnagaddala, Nicholas Hawkins, Junzhou Huang, Erik Meijering
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Computational pathology is a rapidly expanding area for research due to the current global transformation of histopathology through the adoption of digital workflows. Survival prediction of breast cancer patients is an important task that cu
Externí odkaz:
https://doaj.org/article/f4c314d9cc1a4265a0a2e2bc087eee51
Autor:
James Wang, Lois Browne, Iveta Slapetova, Fei Shang, Kirsty Lee, Jodi Lynch, Julia Beretov, Renee Whan, Peter H. Graham, Ewan K. A. Millar
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Triple negative breast cancer (TNBC) comprises 10–15% of all breast cancers and has a poor prognosis with a high risk of recurrence within 5 years. PD-L1 is an important biomarker for patient selection for immunotherapy but its cellular ex
Externí odkaz:
https://doaj.org/article/34c61617586b40f799dbf32a01b62a1c
Autor:
Andrew M. K. Law, Jiamin Chen, Yolanda Colino‐Sanguino, Laura Rodriguez de la Fuente, Guocheng Fang, Susan M. Grimes, Hongxu Lu, Robert J. Huang, Sarah T. Boyle, Jeron Venhuizen, Lesley Castillo, Javad Tavakoli, Joanna N. Skhinas, Ewan K. A. Millar, Julia Beretov, Fernando J. Rossello, Joanne L. Tipper, Christopher J. Ormandy, Michael S. Samuel, Thomas R. Cox, Luciano Martelotto, Dayong Jin, Fatima Valdes‐Mora, Hanlee P. Ji, David Gallego‐Ortega
Publikováno v:
Advanced Science, Vol 9, Iss 21, Pp n/a-n/a (2022)
Abstract To fully investigate cellular responses to stimuli and perturbations within tissues, it is essential to replicate the complex molecular interactions within the local microenvironment of cellular niches. Here, the authors introduce Alginate
Externí odkaz:
https://doaj.org/article/7c01605cf8c442bb9c5423b06b6545f3
Autor:
Raktim Kumar Mondol, Ewan K. A. Millar, Peter H. Graham, Lois Browne, Arcot Sowmya, Erik Meijering
Publikováno v:
Cancers, Vol 15, Iss 9, p 2569 (2023)
Gene expression can be used to subtype breast cancer with improved prediction of risk of recurrence and treatment responsiveness over that obtained using routine immunohistochemistry (IHC). However, in the clinic, molecular profiling is primarily use
Externí odkaz:
https://doaj.org/article/f91bb621789a488aa1a687c3768a473c
Autor:
Yingshi Li, Fan Zhang, Huimin Zheng, Sanjna Kalasabail, Chloe Hicks, Ka Yee Fung, Adele Preaudet, Tracy Putoczki, Julia Beretov, Ewan K. A. Millar, Emad El-Omar, Xiao-Tao Jiang, Howard Chi Ho Yim
Publikováno v:
Pathogens, Vol 11, Iss 4, p 457 (2022)
Alteration of the gut virome has been associated with colorectal cancer (CRC); however, when and how the alteration takes place has not been studied. Here, we employ a longitudinal study in mice to characterize the gut virome alteration in azoxymetha
Externí odkaz:
https://doaj.org/article/4947a9ec101b4ab9a7c16332933b2784
Autor:
Wee S. Teo, Holly Holliday, Nitheesh Karthikeyan, Aurélie S. Cazet, Daniel L. Roden, Kate Harvey, Christina Valbirk Konrad, Reshma Murali, Binitha Anu Varghese, Archana P. Thankamony, Chia-Ling Chan, Andrea McFarland, Simon Junankar, Sunny Ye, Jessica Yang, Iva Nikolic, Jaynish S. Shah, Laura A. Baker, Ewan K. A. Millar, Matthew J. Naylor, Christopher J. Ormandy, Sunil R. Lakhani, Warren Kaplan, Albert S. Mellick, Sandra A. O'Toole, Alexander Swarbrick, Radhika Nair
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Breast cancers display phenotypic and functional heterogeneity and several lines of evidence support the existence of cancer stem cells (CSCs) in certain breast cancers, a minor population of cells capable of tumor initiation and metastatic dissemina
Externí odkaz:
https://doaj.org/article/2535bb7b93e94bffa1b48aa93c0aa118
Publikováno v:
Case Reports in Dermatological Medicine, Vol 2012 (2012)
Inflammatory breast carcinoma is a rare form of advanced breast cancer which carries a poor prognosis, even with treatment. Diagnosis is reached on clinical and pathological grounds; however, due to its propensity to mimic other conditions, it may of
Externí odkaz:
https://doaj.org/article/7791c1ead30a46ac934535e536f80153
Autor:
Elena, López-Knowles, Sandra A, O'Toole, Catriona M, McNeil, Ewan K A, Millar, Min R, Qiu, Paul, Crea, Roger J, Daly, Elizabeth A, Musgrove, Robert L, Sutherland
Publikováno v:
International journal of cancer. 126(5)
Breast cancer is a common malignancy with current biological therapies tailored to steroid hormone (ER, PR) and HER2 receptor status. Understanding the biological basis of resistance to current targeted therapies and the identification of new potenti