Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Ewan C. McNay"'
Publikováno v:
Frontiers in Psychology, Vol 9 (2018)
The brain’s reliance on glucose as a primary fuel source is well established, but psychological models of cognitive processing that take energy supply into account remain uncommon. One exception is research on self-control depletion, where debate c
Externí odkaz:
https://doaj.org/article/69d95bfab4d24be0a228ca0c693d2dc7
Autor:
Corey J. Frank, Ewan C. McNay
Publikováno v:
J Neuroendocrinol
Metabolic disorders (MDs), including type-1 and 2 diabetes (T2DM) and chronic obesity, are among the faster growing diseases globally and are a primary risk factor for Alzheimer’s disease (AD). The term “type-3 diabetes” has been proposed for A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa05787151a6a1043ef4b8cc0104949a
https://europepmc.org/articles/PMC8791015/
https://europepmc.org/articles/PMC8791015/
Publikováno v:
Behavioural Brain Research. 338:32-39
The insulin-regulated glucose transporter, GluT4, is a key molecule in peripheral insulin signaling. Although GluT4 is abundantly expressed in neurons of specific brain regions such as the hippocampus, the functional role of neuronal GluT4 is unclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::644f3a9be2941d9e2476dacb1d0107b2
https://doi.org/10.1016/j.bbr.2017.09.033
https://doi.org/10.1016/j.bbr.2017.09.033
Autor:
Jiah Pearson-Leary, Ewan C. McNay
Publikováno v:
Exp Neurol
Insulin is now well-established as playing multiple roles within the brain, and specifically as regulating hippocampal cognitive processes and metabolism. Impairments to insulin signaling, such as those seen in type 2 diabetes and Alzheimer’s disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1598f98eb93b2fbf3ad1ec05fb684cf9
https://pubmed.ncbi.nlm.nih.gov/31614121
https://pubmed.ncbi.nlm.nih.gov/31614121
Publikováno v:
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 254:119603
There is an urgent clinical need for a fast and effective method for diagnosing Alzheimer’s disease (AD). The identification of AD in its most initial stages, at which point treatment could provide maximum therapeutic benefits, is not only likely t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21938f48c14ded3bac4f9d180bd6bc59
https://doi.org/10.1016/j.saa.2021.119603
https://doi.org/10.1016/j.saa.2021.119603
Autor:
Ewan C. McNay, Jiah Pearson-Leary
Publikováno v:
The Journal of Neuroscience. 36:11851-11864
The insulin-regulated glucose transporter-4 (GluT4) is critical for insulin- and contractile-mediated glucose uptake in skeletal muscle. GluT4 is also expressed in some hippocampal neurons, but its functional role in the brain is unclear. Several est
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2caec14170f15e885f363d0ba64a77e1
https://doi.org/10.1523/jneurosci.1700-16.2016
https://doi.org/10.1523/jneurosci.1700-16.2016
Autor:
Danielle M. Osborne, Ewan C. McNay, Peter M. Tessier, Brian M. Anderson, Dennis P. Fitzgerald, Kelsey E. O’Leary, Christine C. Lee
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1860:1291-1298
Background The prevalence of high fat diets (HFD), diet-induced obesity (DIO) and Type 2 diabetes continues to increase, associated with cognitive impairment in both humans and rodent models. Mechanisms transducing these impairments remain largely un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93962907aa20ed0d44ea9873593ec8da
https://doi.org/10.1016/j.bbagen.2016.03.005
https://doi.org/10.1016/j.bbagen.2016.03.005
Publikováno v:
Behavioural brain research. 333
Zinc and copper are essential trace elements. Dyshomeostasis in these two metals has been observed in Alzheimer's disease, which causes profound cognitive impairment. Insulin therapy has been shown to enhance cognitive performance; however, recent da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f63eff303357d334ef53c5b48072610
https://pubmed.ncbi.nlm.nih.gov/28693861
https://pubmed.ncbi.nlm.nih.gov/28693861
Publikováno v:
Behavioural Brain Research. 245:83-87
There is a long-standing debate as to whether the memory process of consolidation is neurochemically similar to or the same as the set of processes involved in retrieval and reconsolidation of that memory. In addition, although we have previously sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edb416d2f8e7d4215e4443cd57f3dfd5
https://doi.org/10.1016/j.bbr.2013.02.006
https://doi.org/10.1016/j.bbr.2013.02.006