RUBIC identifies driver genes by detecting recurrent DNA copy number breaks

Autor: Ewald van Dyk, Marlous Hoogstraat, Jelle ten Hoeve, Marcel J. T. Reinders, Lodewyk F. A. Wessels

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)

Analysis of cancer genome sequencing data has been used to predict genes associated with the pathogenesis of cancer. Here, the authors propose a new algorithm entitled RUBIC that predicts breaks in DNA as opposed to previously published methods that

Externí odkaz: https://doaj.org/article/23bfe5c1359c422db01ba4741610b336

Supra-second interval timing in bipolar disorder: examining the role of disorder sub-type, mood, and medication status.

Autor: Müller Ewald VA; Department of Psychiatry, The University of Iowa, Iowa City, Iowa, United States of America.; Iowa Neuroscience institute, The University of Iowa, Iowa City, Iowa, United States of America., Trapp NT; Department of Psychiatry, The University of Iowa, Iowa City, Iowa, United States of America.; Iowa Neuroscience institute, The University of Iowa, Iowa City, Iowa, United States of America., Sarrett ME; Department of Psychological and Brain sciences, Villanova University, Villanova, Pennsylvania, United States of America., Pace BD; Department of Psychiatry, The University of Iowa, Iowa City, Iowa, United States of America., Wendt L; Institute for Clinical and Translational Science, The University of Iowa, Iowa City, Iowa, United States of America., Richards JG; Department of Radiology, The University of Iowa, Iowa City, Iowa, United States of America., Gala IK; Department of Psychiatry, The University of Iowa, Iowa City, Iowa, United States of America., Miller JN; St. Luke's Hospital, Cedar Rapids, Iowa, United States of America., Wessel JR; Department of Psychological & Brain sciences, The University of Iowa, Iowa City, Iowa, United States of America.; Department of Neurology, The University of Iowa, Iowa City, Iowa, United States of America.; Iowa Neuroscience institute, The University of Iowa, Iowa City, Iowa, United States of America., Magnotta VA; Department of Psychiatry, The University of Iowa, Iowa City, Iowa, United States of America.; Department of Radiology, The University of Iowa, Iowa City, Iowa, United States of America.; Iowa Neuroscience institute, The University of Iowa, Iowa City, Iowa, United States of America., Wemmie JA; Department of Psychiatry, The University of Iowa, Iowa City, Iowa, United States of America.; Department of Molecular Physiology and Biophysics, The University of Iowa, Iowa City, Iowa, United States of America.; Department of Neurosurgery, The University of Iowa, Iowa City, Iowa, United States of America.; Iowa Neuroscience institute, The University of Iowa, Iowa City, Iowa, United States of America., Boes AD; Department of Psychiatry, The University of Iowa, Iowa City, Iowa, United States of America.; Department of Pediatrics, The University of Iowa, Iowa City, Iowa, United States of America.; Iowa Neuroscience institute, The University of Iowa, Iowa City, Iowa, United States of America., Parker KL; Department of Psychiatry, The University of Iowa, Iowa City, Iowa, United States of America.; Iowa Neuroscience institute, The University of Iowa, Iowa City, Iowa, United States of America.

Publikováno v: Research square [Res Sq] 2023 Jun 02. Date of Electronic Publication: 2023 Jun 02.

Response-contingent optogenetics to discover the mechanisms of nicotine-cue associations.

Autor: Müller Ewald VA; Interdisciplinary Neuroscience Program, Iowa City, IA, 52242, USA. victoriaaugusta-mullerewald@uiowa.edu.; Department of Psychological and Brain Sciences, University of Iowa, Iowa City, IA, 52242, USA. victoriaaugusta-mullerewald@uiowa.edu., LaLumiere RT; Interdisciplinary Neuroscience Program, Iowa City, IA, 52242, USA.; Department of Psychological and Brain Sciences, University of Iowa, Iowa City, IA, 52242, USA.; Iowa Neuroscience Institute, University of Iowa, Iowa City, IA, 52242, USA.

Publikováno v: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2019 Nov; Vol. 44 (12), pp. 1995-1996. Date of Electronic Publication: 2019 Aug 05.

Neural systems mediating the inhibition of cocaine-seeking behaviors.

Autor: Muller Ewald VA; Interdisciplinary Neuroscience Program, University of Iowa, Iowa City, IA 52242, United States. Electronic address: victoriaaugusta-mullerewald@uiowa.edu., LaLumiere RT; Interdisciplinary Neuroscience Program, University of Iowa, Iowa City, IA 52242, United States; Department of Psychological and Brain Sciences, University of Iowa, Iowa City, IA 52242, United States.

Publikováno v: Pharmacology, biochemistry, and behavior [Pharmacol Biochem Behav] 2018 Nov; Vol. 174, pp. 53-63. Date of Electronic Publication: 2017 Jul 15.

Delta-frequency stimulation of cerebellar projections can compensate for schizophrenia-related medial frontal dysfunction.

Autor: Parker KL; Department of Psychiatry, The University of Iowa, Iowa City, IA, USA., Kim YC; Department of Neurology, The University of Iowa, Iowa City, IA, USA., Kelley RM; Department of Neurology, The University of Iowa, Iowa City, IA, USA., Nessler AJ; Department of Psychiatry, The University of Iowa, Iowa City, IA, USA., Chen KH; Institute of Personality and Social Research, University of California, Berkeley, Berkeley, CA, USA., Muller-Ewald VA; Department of Psychology, The University of Iowa, Iowa City, IA, USA., Andreasen NC; Department of Psychiatry, The University of Iowa, Iowa City, IA, USA., Narayanan NS; Department of Neurology, The University of Iowa, Iowa City, IA, USA.

Publikováno v: Molecular psychiatry [Mol Psychiatry] 2017 May; Vol. 22 (5), pp. 647-655. Date of Electronic Publication: 2017 Mar 28.