Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ewald A. W. J. Dumont"'
Autor:
Gerard M. J. Bos, Lenoard Hofstra, Christopher P M Reutelingsperger, Ewald A. W. J. Dumont, Suzanne P M Lutgens
Publikováno v:
Journal of Reconstructive Microsurgery, 26(8), 523-528. Thieme Medical Publishers
For breast reconstruction, the deep inferior epigastric perforator (DIEP) flap has become standard therapy. A feared complication is partial or even total flap loss. In a novel murine model of partial DIEP flap loss, the contribution of apoptotis to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5e8f1bd5a6d459771d0f8842b2e1e7e
https://doi.org/10.1055/s-0030-1262952
https://doi.org/10.1055/s-0030-1262952
Autor:
Artiom Petrov, Chris P. M. Reutelingsperger, Francis Blankenberg, Neena B. Haider, Harmen Reinier Zandbergen, Ewald A. W. J. Dumont, Nicole Bitsch, Leonard Hofstra, Navneet Narula, Jagat Narula, Johan W. Verjans, Heidi Kenis, Marion J.J. Gijbels
Publikováno v:
Journal of Nuclear Medicine, 51(2), 259-267. Society of Nuclear Medicine and Molecular Imaging
Ischemic insult to the myocardium is associated with cardiomyocyte apoptosis. Because apoptotic cell death is characterized by phosphatidylserine externalization on cell membrane and annexin-A5 (AA5) avidly binds to phosphatidylserine, we hypothesize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84eccb7f5734fc86b3b109eedd908d50
https://doi.org/10.2967/jnumed.109.068429
https://doi.org/10.2967/jnumed.109.068429
Autor:
Guido A. K. Heidendal, Heidi Kenis, Chris P. M. Reutelingsperger, Paul W. L. Thimister, Hugo van Genderen, Stefan van de Eijnde, Ewald A. W. J. Dumont, Leonard Hofstra
Publikováno v:
Journal of Immunological Methods. 265:123-132
Annexin A5 binds to phosphatidylserine (PS), which is one of the "eat me" signals at the surface of the apoptotic cell. This property has been the driving force for the research of annexin A5 as a probe to measure apoptosis in vitro and in vivo. A no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7850dfe52372b022d5376e615801db7d
https://doi.org/10.1016/s0022-1759(02)00075-3
https://doi.org/10.1016/s0022-1759(02)00075-3
Autor:
Chris P. M. Reutelingsperger, Ewald A. W. J. Dumont, Mat J.A.P. Daemen, Pieter A. Doevendans, Leonard Hofstra, Jos F.M. Smits, Hein J.J. Wellens
Publikováno v:
Nature medicine, 7(12), 1352-1355. Nature Publishing Group
We report a novel real-time imaging model to visualize apoptotic membrane changes of single cardiomyocytes in the injured heart of the living mouse, using fluorescent labeled annexin-V. Annexin-V binds to externalized phosphatidylserine (PS) of cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b09d9d1edcb141562c4f099b9c1ac0a
https://doi.org/10.1038/nm1201-1352
https://doi.org/10.1038/nm1201-1352
Autor:
Ewald A. W. J. Dumont, Peter M. Frederik, Marc A. R. C. Daemen, Stephan van den Eijnde, Leonard Hofstra, Hein J.J. Wellens, Waander L. van Heerde, Chris P. M. Reutelingsperger, Pieter A. Doevendans, Ebo DeMuinck, Mat J.A.P. Daemen, Jos F.M. Smits
Publikováno v:
Circulation. 102:1564-1568
Introduction —Phosphatidylserine (PS) externalization is regarded as one of the earliest hallmarks of cells undergoing programmed cell death. We studied the use of labeled human recombinant annexin-V, a protein selectively binding to PS, to detect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee2c5c511be608d296b58eb9e1f5d93
https://doi.org/10.1161/01.cir.102.13.1564
https://doi.org/10.1161/01.cir.102.13.1564
Autor:
Ing Han Liem, Hein J.J. Wellens, Hendrikus H. Boersma, W.L. van Heerde, Ewald A. W. J. Dumont, Chris P. M. Reutelingsperger, Guido A. K. Heidendal, Pieter A. Doevendans, Leonard Hofstra, Gerrit J. Kemerink, E De Muinck
Publikováno v:
The Lancet. 356:209-212
Summary Background In-vivo visualisation and quantification of the extent and time-frame of cell death after acute myocardial infarction would be of great interest. We studied in-vivo cell death in the hearts of patients with an acute myocardial infa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b10feedae8db89ae81f6b46e653eaecd
https://doi.org/10.1016/s0140-6736(00)02482-x
https://doi.org/10.1016/s0140-6736(00)02482-x
Autor:
Chris P. M. Reutelingsperger, S.W. Goei, Antonius L.J.J. Bronckers, D.M. Lyaruu, W.L. van Heerde, J.H.M. Wöltgens, S. M. van den Eijnde, Ewald A. W. J. Dumont
Publikováno v:
Histochemistry and Cell Biology, 113, 293-301. Springer Verlag
Bronckers, A L J J, Goei, S W, Dumont, E, Lyaruu, D M, Wöltgens, J H M, van Heerde, W L, Reutelingsperger, C P M & van den Eijnde, S M 2000, ' In situ detection of apoptosis in dental and periodontal tissues of the adult mouse using annexin-V-biotin ', Histochemistry and Cell Biology, vol. 113, pp. 293-301 .
Bronckers, A L J J, Goei, S W, Dumont, E, Lyaruu, D M, Wöltgens, J H M, van Heerde, W L, Reutelingsperger, C P M & van den Eijnde, S M 2000, ' In situ detection of apoptosis in dental and periodontal tissues of the adult mouse using annexin-V-biotin ', Histochemistry and Cell Biology, vol. 113, pp. 293-301 .
An early event in apoptosis is exposure of phosphatidylserine, an aminophospholipid normally present in the inner leaflet of the plasma membranes, at the outer leaflet of the plasma membrane facing the extracellular space. Annexin V (Anx-V) is a 35-k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30e796bf858400014f17755a63347300
https://doi.org/10.1007/s004180000137
https://doi.org/10.1007/s004180000137
Autor:
S. Robert-Offerman, Leonard Hofstra, Mat J.A.P. Daemen, Ewald A. W. J. Dumont, Chris P. M. Reutelingsperger, Pieter A. Doevendans, Jos F.M. Smits, W.L. van Heerde
Publikováno v:
Cardiovascular Research. 45:549-559
In the last decade, apoptosis (or programmed cell death) has become appreciated as an important process in the development of the cardiovascular system. Moreover, apoptosis contributes to the adaptation of the system to the environment. We are at the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fac80746db84c59971fa3b69faa1294
https://doi.org/10.1016/s0008-6363(99)00396-x
https://doi.org/10.1016/s0008-6363(99)00396-x
Autor:
Antonius L.J.J. Bronckers, S. M. van den Eijnde, Ewald A. W. J. Dumont, Chris P. M. Reutelingsperger, W. Goei, W.L. van Heerde
Publikováno v:
Bronckers, A L J J, Goei, S W, van Heerde, W L, Dumont, E A W J, Reutelingsperger, C P M & van den Eijnde, S M 2000, ' Phagocytosis of dying chondrocytes by osteoclasts in the mouse growth plate as demonstrated by annexin-V labelling ', Cell and Tissue Research, vol. 301, pp. 267-272 . https://doi.org/10.1007/s004410000238
Cell and Tissue Research, 301, 267-272. Springer Verlag
Cell and Tissue Research, 301, 267-272. Springer Verlag
Endochondral ossification in the epiphyseal growth plate of long bones is associated with programmed cell death (PCD) of a major portion of the chondrocytes. Here we tested the hypothesis that at the ossification front of the epiphyseal growth plate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d5d39473481816de85af46c7e0661a2
https://research.vu.nl/en/publications/885f3b70-1abc-4364-b6ac-7d732da2078a
https://research.vu.nl/en/publications/885f3b70-1abc-4364-b6ac-7d732da2078a
Publikováno v:
Cardiovascular toxicology. 3(3)
The role of apoptosis in ischemia and reperfusion of the heart has been widely debated. This controversy has been continued because of the lack of an apoptosis detection method that allowed obtaining detailed kinetic and quantitative information on a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::293e21f103e2619cd4aa31499ae082b3
https://pubmed.ncbi.nlm.nih.gov/14555787
https://pubmed.ncbi.nlm.nih.gov/14555787