Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ewa Szczurowska"'
Autor:
Libor Uttl, Ewa Szczurowska, Kateřina Hájková, Rachel R. Horsley, Kristýna Štefková, Tomáš Hložek, Klára Šíchová, Marie Balíková, Martin Kuchař, Vincenzo Micale, Tomáš Páleníček
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Synthetic cannabinoid compounds are marketed as “legal” marijuana substitutes, even though little is known about their behavioral effects in relation to their pharmacokinetic profiles. Therefore, in the present study we assessed the behavioral ef
Externí odkaz:
https://doaj.org/article/d592fc1c94ea489191af302648c0b3bd
Publikováno v:
Neurobiology of learning and memory.
Formation and consolidation of memories for highly stressful (traumatic) events is a complex process that involves interplay between multiple memory systems and has implications for etiology and treatment of stress- and trauma-related disorders. Here
Autor:
Ewa Szczurowska, Eszter Szánti-Pintér, Nikolai Chetverikov, Alena Randáková, Eva Kudová, Jan Jakubík
Publikováno v:
International Journal of Molecular Sciences. 24:507
Muscarinic acetylcholine receptors expressed in the central nervous system mediate various functions, including cognition, memory, or reward. Therefore, muscarinic receptors represent potential pharmacological targets for various diseases and conditi
Allosteric Modulation of Muscarinic Receptors by Cholesterol, Neurosteroids and Neuroactive Steroids
Publikováno v:
International Journal of Molecular Sciences. 23:13075
Muscarinic acetylcholine receptors are membrane receptors involved in many physiological processes. Malfunction of muscarinic signaling is a cause of various internal diseases, as well as psychiatric and neurologic conditions. Cholesterol, neurostero
Formation and consolidation of memories for highly stressful (traumatic) events is a complex process that involves interplay between multiple memory systems and has implications for etiology and treatment of stress- and trauma-related disorders. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6d421585410cb12ad401371b39d0400
https://doi.org/10.1101/2021.08.30.458150
https://doi.org/10.1101/2021.08.30.458150
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 81:275-283
The discoordination hypothesis of schizophrenia posits discoordination of neural activity as the central mechanism that underlies some psychotic symptoms (including 'hallmark' cognitive symptoms) of schizophrenia. To test this proposition, we studied
Autor:
Pavel Mareš, Ewa Szczurowska
Publikováno v:
Brain Research Bulletin. 111:1-8
Ro 25-6981 maleate is a highly selective and activity-dependent antagonist of NMDA ionotropic glutamate receptors containing NR2B subunit (NR2B/NMDARs). The aim of our study was to investigate the influence of Ro 25-6981 administration in developing
Autor:
Pavel Mareš, Ewa Szczurowska
Publikováno v:
ResearcherID
Glutamate is the main excitatory neurotransmitter in the brain and ionotropic glutamate receptors mediate the majority of excitatory neurotransmission (Dingeldine et al. 1999). The high level of glutamatergic excitation allows the neonatal brain (the
Autor:
Pavel Mareš, Ewa Szczurowska
Publikováno v:
European Journal of Pharmacology. 623:37-40
Some age-dependent epilepsies of infancy and childhood cannot be sufficiently treated with contemporaneous antiepileptics, therefore search for new mechanisms and new drugs active in pediatric patients is necessary. Possible anticonvulsant action of
Publikováno v:
Experimental neurology. 283
AMPA receptors (AMPARs) are responsible for fast excitatory neurotransmission, and their prolonged activation can result in the generation and spread of epileptic seizures. At early stages of postnatal development, the majority of AMPARs are permeabl