Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Ewa Sitnicka"'
Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction
Autor:
Fatemeh Safi, Parashar Dhapola, Sarah Warsi, Mikael Sommarin, Eva Erlandsson, Jonas Ungerbäck, Rebecca Warfvinge, Ewa Sitnicka, David Bryder, Charlotta Böiers, Ram Krishna Thakur, Göran Karlsson
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113357- (2023)
Externí odkaz:
https://doaj.org/article/afa99b9a000946b79b1053681bd6ceed
Autor:
Maria Jassinskaja, Kristýna Pimková, Nejc Arh, Emil Johansson, Mina Davoudi, Carlos-Filipe Pereira, Ewa Sitnicka, Jenny Hansson
Publikováno v:
Cell Reports, Vol 34, Iss 12, Pp 108894- (2021)
Summary: The process of hematopoiesis is subject to substantial ontogenic remodeling that is accompanied by alterations in cellular fate during both development and disease. We combine state-of-the-art mass spectrometry with extensive functional assa
Externí odkaz:
https://doaj.org/article/cf5b5f27760c4796b3e9796e54bf9bee
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/e0768cc3567b4eed939d71bbf15d566e
Autor:
Roksana Moraghebi, Agnete Kirkeby, Patricia Chaves, Roger E. Rönn, Ewa Sitnicka, Malin Parmar, Marcus Larsson, Andreas Herbst, Niels-Bjarne Woods
Publikováno v:
Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-12 (2017)
Abstract Background Mesenchymal stromal cells (MSCs) are currently being evaluated in numerous pre-clinical and clinical cell-based therapy studies. Furthermore, there is an increasing interest in exploring alternative uses of these cells in disease
Externí odkaz:
https://doaj.org/article/adba637cebd44013a326c5d4fffa323c
Autor:
Adam J. Mead, Shabnam Kharazi, Deborah Atkinson, Iain Macaulay, Christian Pecquet, Stephen Loughran, Michael Lutteropp, Petter Woll, Onima Chowdhury, Sidinh Luc, Natalija Buza-Vidas, Helen Ferry, Sally-Ann Clark, Nicolas Goardon, Paresh Vyas, Stefan N. Constantinescu, Ewa Sitnicka, Claus Nerlov, Sten Eirik W. Jacobsen
Publikováno v:
Cell Reports, Vol 3, Iss 6, Pp 1766-1776 (2013)
Whether signals mediated via growth factor receptors (GFRs) might influence lineage fate in multipotent progenitors (MPPs) is unclear. We explored this issue in a mouse knockin model of gain-of-function Flt3-ITD mutation because FLT3-ITDs are paradox
Externí odkaz:
https://doaj.org/article/703445d2063749ebb29c59b6e36d5091
Publikováno v:
The Journal of Immunology. 205:1830-1841
The β-catenin/Wnt signaling pathway plays an important role in all stages of T cell development. Nemo-like kinase (NLK) is an evolutionary conserved serine/threonine kinase and a negative regulator of the Wnt signaling pathway. NLK can directly phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c480179397228ee07959259ff18fda08
https://doi.org/10.4049/jimmunol.2000109
https://doi.org/10.4049/jimmunol.2000109
3204 – NK CELL-DEFECTS OCCURRING ALREADY AT THE PRE-MDS STAGE IN NUP98-HOXD13 TRANSGENIC MOUSE MODEL
Autor:
Gladys Telliam Dushime, Ouyang Yuan, Olga Kotova, Maciej Ciesla, Henrik Lilljebjörn, Jonas Ungerbäck, Thoas Fioretos, Cristian Bellodi, David Bryder, Ewa Sitnicka
Publikováno v:
Experimental Hematology. 111:S146-S147
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::671d56ae531921534a616403aa4b2e52
https://doi.org/10.1016/j.exphem.2022.07.260
https://doi.org/10.1016/j.exphem.2022.07.260
Autor:
David Bryder, Isabella Artner, Rashmi B. Prasad, Luis Sarmiento, Malin Fex, Ewa Sitnicka, Monika Dudenhöffer-Pfeifer, Luis Rodrigo Cataldo, P. Chaves, Tania Singh, Lisbeth Hansen, Sara Bsharat, Corrado M. Cilio, Jesper K. Colberg, Dan Holmberg
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports
Maf transcription factors are critical regulators of beta-cell function. We have previously shown that reduced MafA expression in human and mouse islets is associated with a pro-inflammatory gene signature. Here, we investigate if the loss of Maf tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eafaa88e71a4759047f1b4b2652e143a
http://link.springer.com/article/10.1038/s41598-019-45528-x
http://link.springer.com/article/10.1038/s41598-019-45528-x
Autor:
Sten Eirik W. Jacobsen, Lilian Wittmann, Hanane Boukarabila, Claudia Peitzsch, Alya Zriwil, P. Chaves, Ewa Sitnicka
Publikováno v:
The Journal of Immunology. 201:3307-3319
Within the hematopoietic system, the Notch pathway is critical for promoting thymic T cell development and suppressing the B and myeloid lineage fates; however, its impact on NK lymphopoiesis is less understood. To study the role of Notch during NK c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e0c0f89dd4ae42c7232157ee33255b8
https://doi.org/10.4049/jimmunol.1701675
https://doi.org/10.4049/jimmunol.1701675
Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction
Autor:
Fatemeh, Safi, Parashar, Dhapola, Sarah, Warsi, Mikael, Sommarin, Eva, Erlandsson, Jonas, Ungerbäck, Rebecca, Warfvinge, Ewa, Sitnicka, David, Bryder, Charlotta, Böiers, Ram Krishna, Thakur, Göran, Karlsson
Publikováno v:
Cell Reports. 39:110798
The emerging notion of hematopoietic stem and progenitor cells (HSPCs) as a low-primed cloud without sharply demarcated gene expression programs raises the question on how cellular-fate options emerge and at which stem-like stage lineage priming is i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae97807473e6fdc3d3e0ba76dce5a24c
https://doi.org/10.1016/j.celrep.2022.110798
https://doi.org/10.1016/j.celrep.2022.110798