Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Ewa Sicinska"'
Autor:
Lishan Fang, Dane Ford-Roshon, Max Russo, Casey O’Brien, Xiaozhe Xiong, Carino Gurjao, Maximilien Grandclaudon, Srivatsan Raghavan, Steven M. Corsello, Steven A. Carr, Namrata D. Udeshi, James Berstler, Ewa Sicinska, Kimmie Ng, Marios Giannakis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The RNF43 G659fs mutation occurs frequently in colorectal cancer, but its function remains poorly understood. In this study, the authors show that RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibit
Externí odkaz:
https://doaj.org/article/f27b6baf1c414b9d98b4607879f425b8
Publikováno v:
Antioxidants, Vol 12, Iss 10, p 1798 (2023)
This systematic review aims to summarise the results of controlled trials on dietary supplements (DS) usage and inflammation, oxidative stress, antioxidant status, and thyroid parameter improvement in hypothyroidism (HT)/Hashimoto’s thyroiditis (AI
Externí odkaz:
https://doaj.org/article/43f21f8e4a4c44efbf48695f22acaa00
Publikováno v:
Nutrients, Vol 15, Iss 9, p 2131 (2023)
The Mediterranean diet (MD) has been previously proven to have various health-related benefits; however, its effect on women’s reproductive health over a lifespan is yet to be summarized. This study aimed to summarize the evidence-based knowledge r
Externí odkaz:
https://doaj.org/article/2aa56a4e37954147a09e9b4f75b5abd1
Autor:
Joanna Kaluza, Katarzyna Lozynska, Julia Rudzinska, Dominika Granda, Ewa Sicinska, Maria Karolina Szmidt
Publikováno v:
Nutrients, Vol 15, Iss 3, p 725 (2023)
Due to the lack of studies comparing the determinants of well-being in omnivores and vegetarians, we examined associations of socio-demographic and lifestyle factors, including adherence to a Mediterranean-style diet, in relation to well-being in omn
Externí odkaz:
https://doaj.org/article/422eba3e498745ea93575cba254b85c0
Publikováno v:
Frontiers in Nutrition, Vol 8 (2021)
The influence of fruit and vegetable consumption on semen quality by reducing oxidative stress is inconsistent. Thus, the association between the consumption of these products, antioxidant status, and semen quality was investigated in 90 men aged 18
Externí odkaz:
https://doaj.org/article/9a089e6427cc4623b8d7c613c6734a93
Publikováno v:
Nutrients, Vol 14, Iss 13, p 2745 (2022)
The study aimed to examine socio-demographic and lifestyle determinants, including diet quality, of dietary supplement (DS) use among 2545 students who attended public universities in Warsaw. The data was collected using a self-administered health an
Externí odkaz:
https://doaj.org/article/1bd34404b9314d349c14c80f8cc29d31
Autor:
Charlotte S. Kramer, Maria K. Szmidt, Ewa Sicinska, Anna Brzozowska, Aurelia Santoro, Claudio Franceschi, Lisette C. P. G. M. de Groot, Agnes A. M. Berendsen
Publikováno v:
Frontiers in Nutrition, Vol 6 (2019)
Background: In order to prevent age-related degenerative diseases in the aging population, their diets should be nutrient dense. For this purpose, the Elderly-Nutrient rich food (E-NRF7.3) score has been developed to assess nutrient density of diets
Externí odkaz:
https://doaj.org/article/ad213b32087546809646aaa0d30211de
Autor:
Belinda Wang, Elsa Beyer Krall, Andrew James Aguirre, Miju Kim, Hans Ragnar Widlund, Mihir Bhavik Doshi, Ewa Sicinska, Rita Sulahian, Amy Goodale, Glenn Spencer Cowley, Federica Piccioni, John Gerard Doench, David Edward Root, William Chun Hahn
Publikováno v:
Cell Reports, Vol 18, Iss 6, Pp 1543-1557 (2017)
Intrinsic resistance and RTK-RAS-MAPK pathway reactivation has limited the effectiveness of MEK and RAF inhibitors (MAPKi) in RAS- and RAF-mutant cancers. To identify genes that modulate sensitivity to MAPKi, we performed genome-scale CRISPR-Cas9 los
Externí odkaz:
https://doaj.org/article/be8a210ebb1a489e99d35a897dbf44e3
Autor:
Jin Zhou, Zhong Wu, Gabrielle Wong, Eirini Pectasides, Ankur Nagaraja, Matthew Stachler, Haikuo Zhang, Ting Chen, Haisheng Zhang, Jie Bin Liu, Xinsen Xu, Ewa Sicinska, Francisco Sanchez-Vega, Anil K. Rustgi, J. Alan Diehl, Kwok-Kin Wong, Adam J. Bass
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Oesophageal squamous cell carcinoma often develop resistance to EGFR tyrosine kinase inhibitors. Here, the authors demonstrate that inhibition of cell cycle regulators CDK4/6 or MAPK blockade enhances the efficacy of EGFR inhibitors for these tumours
Externí odkaz:
https://doaj.org/article/282f92eea86c444d9bab4d8683fb7b94
Autor:
Enrico Giampieri, Rita Ostan, Giulia Guidarelli, Stefano Salvioli, Agnes A. M. Berendsen, Anna Brzozowska, Barbara Pietruszka, Amy Jennings, Nathalie Meunier, Elodie Caumon, Susan Fairweather-Tait, Ewa Sicinska, Edith J. M. Feskens, Lisette C. P. G. M. de Groot, Claudio Franceschi, Aurelia Santoro
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
In this work we present a novel statistical approach to improve the assessment of the adherence to a 1-year nutritional intervention within the framework of the NU-AGE project. This was measured with a single adherence score based on 7-days food reco
Externí odkaz:
https://doaj.org/article/edcc689d7a194427b28024ec53f74142