Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ewa S. Jakobs"'
Autor:
Carol E. Cass, Ewa S. Jakobs, Francisca R. Agbanyo, Jun-ichi Asakura, Masakatsu Kaneko, Susumu Shibuya, Morris J. Robins, Alan R. P. Paterson
Publikováno v:
Nucleosides and Nucleotides. 13:1627-1646
Four classes of 6-X-benzylated purine nucleosides, (i) 6-N-(substituted-benzyl)adenosines, (ii) 6-N-(4-nitrobenzyl)adenine nucleosides with modified sugars, (iii) 6-N(S)-(4-azidobenzyl) derivatives of adenosine, 6-thioinosine, and 6-thioguanosine, an
Publikováno v:
Japanese Journal of Pharmacology. 52:18
Autor:
Alan R. P. Paterson, Ewa S. Jakobs
Publikováno v:
Biochemical and biophysical research communications. 140(3)
In a simple salts medium, monolayers of IEC-6 intestinal cells achieved concentrations of unmetabolized formycin B (an analog of inosine) about 6-fold higher than in the medium. Rates of formycin B influx were a saturable function of Na+ concentratio
Publikováno v:
Biochemical pharmacology. 31(10)
The i.v. administration of tubercidin, an analog of adenosine, in a single dose of 45 mg/kg caused death in about 90% of B10D2F1 mice so treated. Serum and urine analysis, as well as histological examination of tissues, related the lethality of tuber