Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ewa Raczka"'
Autor:
Andrzej Myc, Ewa Raczka, Anil K. Patri, Lars T. Piehler, James J. Mulé, Thommey P. Thomas, Istvan J. Majoros, Antonio Quintana, James R. Baker, Inhan Lee
Publikováno v:
Pharmaceutical Research. 19:1310-1316
Purpose. We sought to develop nanoscale drug delivery materials that would allow targeted intracellular delivery while having an imaging capability for tracking uptake of the material. A complex nanodevice was designed and synthesized that targets tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b8a857395490bb3b361d0bcac7e4f1c
https://doi.org/10.1023/a:1020398624602
https://doi.org/10.1023/a:1020398624602
Autor:
Lars T. Piehler, James R. Baker, Donald A. Tomalia, Ewa Raczka, Mark Banazak-Holl, Antonio Quintana
Publikováno v:
Biomedical Microdevices. 3:61-69
Nanotechnology provides the sized materials that can be synthesized and function in the same general size range and Biologic structures. We have attempted to develop forms of anticancer therapeutics based on nanomaterials. Our project seeks to develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2aaf01cb1ab68dda5b6fdd2a9584098
https://doi.org/10.1023/a:1011485622697
https://doi.org/10.1023/a:1011485622697
Publikováno v:
Pharmaceutical Research. 18:838-845
Purpose. To examine the effect of changes in plasma α1-acid glycoprotein (AAG) levels on the pharmacokinetics (PK) and pharmacodynamics (PD) of lerisetron, a novel serotonin 5-HT3 receptor antagonist, in the rat.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31900fbde03e425842e1a0fc5e9ea730
https://doi.org/10.1023/a:1011096714860
https://doi.org/10.1023/a:1011096714860
Autor:
Ewa Raczka, Antonio Quintana
Publikováno v:
British Journal of Pharmacology. 126:1325-1332
The effects of intravenous infusion of prostacyclin (PGI2, 0.1, 0.2, 0.3 and 1.0 μg kg−1 min−1 lasting 5 min) on regional blood flow and regional vascular resistance have been studied in awake rats using the radioactive microsphere method. The c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe15dce850091d7ceecde645fe1d7950
https://doi.org/10.1038/sj.bjp.0702426
https://doi.org/10.1038/sj.bjp.0702426
Autor:
Antonio, Quintana, Ewa, Raczka, Lars, Piehler, Inhan, Lee, Andrzej, Myc, Istvan, Majoros, Anil K, Patri, Thommey, Thomas, James, Mulé, James R, Baker
Publikováno v:
Pharmaceutical research. 19(9)
We sought to develop nanoscale drug delivery material that would allow targeted intracellular delivery while having an imaging capability for tracking uptake of the material. A complex nanodevice was designed and synthesized that targets tumor cell t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8294ecbef99db83d148fc36735265ad2
https://pubmed.ncbi.nlm.nih.gov/12403067
https://pubmed.ncbi.nlm.nih.gov/12403067
Autor:
Ewa Raczka, Leire de la Fuente, Elena Suarez, Antonio Quintana, Rosario Calvo, Nerea Jauregizar
Publikováno v:
Gerontology. 49(4)
Background: The importance of studying the effects of age on the pharmacokinetics and pharmacodynamics of lerisetron – a new 5-hydroxytryptamine-3 (serotonin) receptor antagonist – comes from the facts that lerisetron will be administered to pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4340d4e10c7d2ae008277236156a8409
https://pubmed.ncbi.nlm.nih.gov/12792155
https://pubmed.ncbi.nlm.nih.gov/12792155
Autor:
Elena Suarez, Ma Luisa Lucero, Ana Gonzalo, Ewa Raczka, Ignacio F. Trocóniz, Rosario Calvo, Aurelio Orjales, R.M. Jiménez
Publikováno v:
Cancer chemotherapy and pharmacology. 42(5)
The aim of this study was, (1) to characterize the serum protein binding of lerisetron, a new 5-hydroxytryptamine (5-HT3) receptor antagonist under investigation as an antiemetic agent, and (2) to measure the percentage of unbound lerisetron in cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7a33ecda54f756c33e892c8b9616ee
https://pubmed.ncbi.nlm.nih.gov/9771958
https://pubmed.ncbi.nlm.nih.gov/9771958
Publikováno v:
Journal of Pharmaceutical Sciences. 91:41
The pharmacokinetics of lerisetron, a novel 5HT(3) antagonist, are studied together with its efficacy in inhibiting the serotonin (5-HT)-evoked transient bradycardia reflex (von Bezold-Jarisch reflex) in Sprague Dawley rats. [(14)C]Lerisetron (50, 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ede677cb5d9f7002c664bc774357427
https://doi.org/10.1002/jps.1169.abs
https://doi.org/10.1002/jps.1169.abs
Autor:
Ewa Raczka, Antonio Quintana
Publikováno v:
Pharmacological Research. 31:132
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b000148e78dedc097718f81d3de122a
https://doi.org/10.1016/1043-6618(95)86786-4
https://doi.org/10.1016/1043-6618(95)86786-4
Publikováno v:
European Journal of Pharmacology. 149:385-388
Cerebral blood flow (CBF) was measured in conscious rats treated with indomethacin, diclofenac or the vehicle for indomethacin during hypercapnia of three different degrees. Similar values were found for CBF in rats treated with diclofenac or vehicle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91faf94b73f177c55a439aba7ceed747
https://doi.org/10.1016/0014-2999(88)90674-7
https://doi.org/10.1016/0014-2999(88)90674-7