Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Ewa Pol"'
Autor:
Julia Wieruszewska, Aleksandra Pawłowicz, Ewa Połomska, Karol Pasternak, Zofia Gdaniec, Witold Andrałojć
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract DNAzymes – synthetic enzymes made of DNA — have long attracted attention as RNA-targeting therapeutic agents. Yet, as of now, no DNAzyme-based drug has been approved, partially due to our lacking understanding of their molecular mode of
Externí odkaz:
https://doaj.org/article/4c3996cbdb22420299f3ddfd0d491631
Publikováno v:
ChemBioChem. 18:1016-1021
Protein-based pharmaceuticals represent the fastest growing group of drugs in development in the pharmaceutical industry. One of the major challenges in the discovery, development, and distribution of biopharmaceuticals is the assessment of changes i
Publikováno v:
Analytical Biochemistry. 510:88-97
Surface Plasmon Resonance biosensors measure the interaction between a molecule in solution and its interaction partner attached to a sensor surface. Under certain conditions, the observed binding rate can be used directly to obtain the concentration
Autor:
Ewelina Rostkowska, Ewa Poleszak, Agata Przekora, Michał Wójcik, Rafał Typek, Katarzyna Wojciechowska, Katarzyna Dos Santos Szewczyk
Publikováno v:
Molecules, Vol 29, Iss 13, p 3058 (2024)
Skin aging is an inevitable and intricate process instigated, among others, by oxidative stress. The search for natural sources that inhibit this mechanism is a promising approach to preventing skin aging. The purpose of our study was to evaluate the
Externí odkaz:
https://doaj.org/article/87b70d1fd95c4c1cb7292d2926cea444
Autor:
Marta Ostrowska-Leśko, Mariola Herbet, Kamil Pawłowski, Agnieszka Korga-Plewko, Ewa Poleszak, Jarosław Dudka
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5899 (2024)
Chronic variable mild stress (CVS) in rats is a well-established paradigm for inducing depressive-like behaviors and has been utilized extensively to explore potential therapeutic interventions for depression. While the behavioral and neurobiological
Externí odkaz:
https://doaj.org/article/876c452fa3e34292aab232e3f787e448
Autor:
Jaroslaw Szponar, Agnieszka Gorska, Marta Ostrowska-Lesko, Agnieszka Korga-Plewko, Michal Tchorz, Erwin Ciechanski, Anna Dabrowska, Ewa Poleszak, Franciszek Burdan, Jaroslaw Dudka, Marek Murias, Slawomir Mandziuk
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2219 (2024)
Late cardiotoxicity is a formidable challenge in anthracycline-based anticancer treatments. Previous research hypothesized that co-administration of carvedilol (CVD) and dexrazoxane (DEX) might provide superior protection against doxorubicin (DOX)-in
Externí odkaz:
https://doaj.org/article/ba9b79ff7144444a9da2828e5e5386f8
Autor:
Ewa Pol, Andreas Heine, Tobias Wulsdorf, C. Rechlin, Veronica Fridh, Philipp M. Toth, Wibke E. Diederich, Frithjof Martin Scheer, Felix Terwesten, Gerhard Klebe
Publikováno v:
ACS chemical biology. 12(5)
Insights into the thermodynamic and kinetic signature of the transient opening of a protein-binding pocket resulting from accommodation of suitable substituents attached to a given parent ligand scaffold are presented. As a target, we selected human
Autor:
Ewa Pol, Elżbieta Przesmycka
Publikováno v:
Teka Komisji Architektury, Urbanistyki i Studiów Krajobrazowych. 10:33-40
The changes taking place in recent years are particularly evident in small towns. This is due to the scale of development. Any change in the proportion interfere the composition. The traditional wooden architecture in eastern regions of Poland disapp
Autor:
Kajetan Juszczak, Jan Adamowicz, Łukasz Zapała, Tomasz Kluz, Przemysław Adamczyk, Artur Wdowiak, Iwona Bojar, Marcin Misiek, Magdalena Emilia Grzybowska, Klaudia Stangel-Wójcikiewicz, Ewa Poleszak, Marta Pokrywczyńska, Tomasz Drewa, Andrzej Wróbel
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Cyclophosphamide (CYP) damages all mucosal defence lines and induces hemorrhagic cystitis (HC) leading to detrusor overactivity. Patients who undergo combined chemio-radiotherapy are at higher risk of HC. Potentilla chinensis extract (PCE) p
Externí odkaz:
https://doaj.org/article/326a87c7a761412fa2fb3dcb5a2a4e10
Autor:
Paulina Iwaniak, Piotr Dobrowolski, Jan Wróbel, Tomasz Kluz, Artur Wdowiak, Iwona Bojar, Klaudia Stangel-Wójcikiewicz, Ewa Poleszak, Artur Jakimiuk, Marcin Misiek, Łukasz Zapała, Andrzej Wróbel
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15793 (2023)
Overactive bladder syndrome (OAB) is a prevalent condition that affects the elderly population in particular and significantly impairs quality of life. Imperatorin, a naturally occurring furocoumarin, possesses diverse pharmacological properties that
Externí odkaz:
https://doaj.org/article/a9bebbb685a54263a6eb1b89d3242631