Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Ewa Oledzka"'
Autor:
Martyna Zagórska-Dziok, Anna Nowak, Anna Zgadzaj, Ewa Oledzka, Karolina Kędra, Agnieszka Ewa Wiącek, Marcin Sobczak
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5934 (2024)
Dermatology and cosmetology currently prioritize healthy, youthful-looking skin. As a result, research is being conducted worldwide to uncover natural substances and carriers that allow for controlled release, which could aid in the battle against a
Externí odkaz:
https://doaj.org/article/5bf9e2b073c449f280c85b894f208402
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 668 (2024)
Worldwide cancer statistics have indicated about 20 million new cancer cases and over 10 million deaths in 2022 (according to data from the International Agency for Research on Cancer). One of the leading cancer treatment strategies is chemotherapy,
Externí odkaz:
https://doaj.org/article/355a51712bfe4537993dcd16ec6d9fd3
Autor:
Ewa Oledzka
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3398 (2024)
Xanthohumol (Xn), a prenylated chalcone found in Hop (Humulus lupulus L.), has been shown to have potent anti-aging, diabetes, inflammation, microbial infection, and cancer properties. Unfortunately, this molecule has undesirable characteristics such
Externí odkaz:
https://doaj.org/article/12922d455a59488b81686f952b1e3e0a
Autor:
Adam Kasiński, Agata Świerczek, Monika Zielińska-Pisklak, Sebastian Kowalczyk, Andrzej Plichta, Anna Zgadzaj, Ewa Oledzka, Marcin Sobczak
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 6906 (2023)
The aim of this study was to develop an innovative, dual-stimuli-responsive smart hydrogel local drug delivery system (LDDS), potentially useful as an injectable simultaneous chemotherapy and magnetic hyperthermia (MHT) antitumor treatment device. Th
Externí odkaz:
https://doaj.org/article/39bed9f8aebc43f89c3d808a2d780dfc
Poly(amidoamine) Dendrimer/Camptothecin Complex: From Synthesis to In Vitro Cancer Cell Line Studies
Autor:
Ewa Oledzka, Klaudia Paśnik, Izabela Domańska, Monika Zielińska-Pisklak, Urszula Piotrowska, Marcin Sobczak, Łukasz Szeleszczuk, Anna Laskowska
Publikováno v:
Molecules, Vol 28, Iss 6, p 2696 (2023)
Camptothecin (CPT), an alkaloid with potent anticancer activity, is still not used in clinical practice due to its high hydrophobicity, toxicity, and poor active-form stability. To address these shortcomings, our research focuses on the encapsulation
Externí odkaz:
https://doaj.org/article/292f156008d64681836dfffb74eabc4d
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1053 (2023)
Camptothecin (CPT) has demonstrated antitumor activity in lung, ovarian, breast, pancreas, and stomach cancers. However, this drug, like many other potent anticancer agents, is extremely water-insoluble. Furthermore, pharmacology studies have reveale
Externí odkaz:
https://doaj.org/article/ab3371aca148449d8e6bba22b136adf6
Autor:
Maria Bialik, Joanna Proc, Anna Zgadzaj, Karolina Mulas, Marzena Kuras, Marcin Sobczak, Ewa Oledzka
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 13743 (2022)
Thermosensitive liquid suppositories (LSs) carrying the model antihypertensive drug metoprolol tartrate (MT) were developed and evaluated. The fundamental purpose of this work was to produce, for the first time, liquid MT suppositories based on biode
Externí odkaz:
https://doaj.org/article/86b797e3b4f9401b9986e4aba17083bf
Autor:
Izabela M. Domańska, Anna Zgadzaj, Sebastian Kowalczyk, Aldona Zalewska, Ewa Oledzka, Krystyna Cieśla, Andrzej Plichta, Marcin Sobczak
Publikováno v:
Molecules, Vol 27, Iss 3, p 1139 (2022)
Aliphatic polyesters are the most common type of biodegradable synthetic polymer used in many pharmaceutical applications nowadays. This report describes the ring-opening polymerization (ROP) of l-lactide (L-LA), ε-caprolactone (CL) and glycolide (G
Externí odkaz:
https://doaj.org/article/531a37f61a8b4a2fad7c7a5ad14a05c7
Autor:
Adam Kasiński, Monika Zielińska-Pisklak, Sebastian Kowalczyk, Andrzej Plichta, Anna Zgadzaj, Ewa Oledzka, Marcin Sobczak
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 8330 (2021)
In this paper, injectable, thermosensitive smart hydrogel local drug delivery systems (LDDSs) releasing the model antitumour drug 5-fluorouracil (5-FU) were developed. The systems were based on biodegradable triblock copolymers synthesized via ring o
Externí odkaz:
https://doaj.org/article/5b96e46c45d142aebf46c5ae4ea2ee8e
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5500 (2021)
Rectal drug delivery is an effective alternative to oral and parenteral treatments. This route allows for both local and systemic drug therapy. Traditional rectal dosage formulations have historically been used for localised treatments, including lax
Externí odkaz:
https://doaj.org/article/00a70a827df1420c9e7d4e21b7b0a5ab