Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ewa Nauka"'
Publikováno v:
Journal of Pharmaceutical Sciences. 110:2669-2676
In tablet manufacturing, mixing operations in tumble blending (TB) and in the feed frame (FF) of the rotary press can both increase lubricity, negatively influencing the tablet mechanical strength. While the TB-driven lubrication was systematically s
Publikováno v:
Journal of pharmaceutical sciences. 110(3)
The purpose of this study is to assess the prevalence of funnel flow pattern for common pharmaceutical powder blends, upon discharging from modern intermediate bulk containers (IBCs) in drug product manufacturing. The estimation was built upon Jenike
Publikováno v:
Journal of pharmaceutical sciences. 109(6)
Multiple pharmaceutical powder processes operate at stresses lower than utilized in typical lab-scale shear cell testing. To bridge this gap, we developed a method to determine intrinsic powder flow properties, in particular, flow function (FFc), und
Accelerated predictive stability approaches are increasingly used in the pharmaceutical industry to make important decisions about formulation selection, shelf-life assignment, and packaging configuration. These approaches most often focus on chemica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5933f7a54159a0dfc35799488f87d132
https://doi.org/10.1016/b978-0-12-802786-8.00018-8
https://doi.org/10.1016/b978-0-12-802786-8.00018-8
Autor:
Anjali Agrawal, Stan Altan, Steven W. Baertschi, Chandan Bhugra, Ricardo Borjas, John Campbell, Dana Carabillo, Juan Chen, Lilan H. Chen, Donald Clancy, Elise Clement, Stephen T. Colgan, David Curran, Gena Dalziel, Mayur Dudhedia, Sudharsan Dwaraknath, Anita L. Freed, Paul Gerst, Michael Hawley, Evan M. Hetrick, Cherokee S. Hoaglund Hyzer, Gordon Hutton, Madhuri Jerfy, Satish Kamath, Ammar Khawam, Todd Lewis, Hanlin Li, Julie Lippke, Bruce C. MacDonald, Llurellyn Malcolm, Keith Masse, Tony Mazzeo, Andrew P. Monahan, Ewa Nauka, Rachel Orr, Brian W. Pack, Jeegna Patel-Jones, Jackson D. Pellett, William R. Porter, Fenghe Qiu, Jeffrey C. Roberts, Samantha Rusk, Kevin O. Ryan, Kevin Ryan, Robert Schwabe, Garry Scrivens, Ashish Soman, Jon T. Swanson, Zhixin Jessica Tan, Martyn Ticehurst, Robert J. Timpano, Bryan S. Wicks, Zeena Williams, Chad N. Wolfe, Gavin Wood, Zufan Steven Wu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddf3d76a1a8cc8978d2bef65c0f977b9
https://doi.org/10.1016/b978-0-12-802786-8.09988-5
https://doi.org/10.1016/b978-0-12-802786-8.09988-5
Publikováno v:
Pharmaceutical research. 35(2)
The purpose of this work is to investigate the effect of microenvironmental pH modulation on the in vitro dissolution rate and oral absorption of GDC-0810, an oral anti-cancer drug, in human. The pH-solubility profile of GDC-0810 free acid and pHmax
Autor:
John Latour, Rosa P. Ubillas, Joaquin Randle, Donald Bierer, R. Eric Gerber, Shivanand D. Jolad, Jeffrey M. Dener, Diana M. Fort, Ewa Nauka
Publikováno v:
The Journal of Organic Chemistry. 60:7022-7026
Publikováno v:
Drug development and industrial pharmacy. 39(7)
Granulation technologies are widely used in solid oral dosage forms to improve the physical properties during manufacture. Wet, dry, and melt granulation techniques were assessed for Compound A, a BCS class II compound. Characterization techniques we
Autor:
Anant Shanbhag, Paul Mansky, Shelley R. Rabel, Padmaja Shivanand, Ewa Nauka, Gemma Casadevall, Gary Eichenbaum
Publikováno v:
International journal of pharmaceutics. 351(1-2)
An efficient method has been developed for screening solid dispersion formulations that are intended to enhance the dissolution of poorly soluble compounds. The method is based on miniaturization and automation of sample preparation by solvent castin