Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ewa Mironiuk-Puchalska"'
Autor:
Ewa Mironiuk-Puchalska, Izabela D. Madura, Paulina H. Marek, Tomasz Rowicki, Wojciech Sas, Karolina Kopczyńska
Publikováno v:
Journal of Molecular Structure. 1183:14-23
Dispiro derivative of 7-oxa-1-azabicyclo [2.2.1]heptane 5 was synthesized as a single stereoisomer from N-(5-allyl-spiro [1,3-dioxan-2,1′-cyclohexane]-5-yl)hydroxylamine 2 and protected d -mannose 3, through intramolecular 1,3-dipolar cycloaddition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0ce9714349887da9e5239f35334d397
https://doi.org/10.1016/j.molstruc.2019.01.058
https://doi.org/10.1016/j.molstruc.2019.01.058
Publikováno v:
Organic Process Research & Development. 21:885-889
A novel protocol for preparation of tegafur (a prodrug of 5-fluorouracil) is reported. The process involves the 1,8-diazabicycloundec-7-ene-mediated alkylation of 5-fluorouracil with 2-acetoxytetrahydrofuran at 90 °C, followed by treatment of the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5b53f7c8b8935d531d476bd0bc5c730
https://doi.org/10.1021/acs.oprd.7b00103
https://doi.org/10.1021/acs.oprd.7b00103
Autor:
Ewa Mironiuk-Puchalska, Jolanta Ignatowska, Maria Bretner, Mariola Koszytkowska-Stawińska, Piotr Grześkowiak, Patrycja Wińska, Monika Wielechowska, Olena Karatsai, Maria Jolanta Redowicz
Publikováno v:
Bioorganic Chemistry
Three series of the β-pyrimidine alanines, including willardiine - a naturally occurring amino acid, were prepared from the l -serine-derived sulfamidates. Compounds 3b, 4a and 4b demonstrated antiproliferative activity toward the studied cancer cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33438ac10ee5e1c3842f269f2225c55f
Autor:
Maria Bretner, Maria Jolanta Redowicz, Ewa Mironiuk-Puchalska, Monika Wielechowska, Włodzimierz Buchowicz, Piotr Grześkowiak, Patrycja Wińska, Mariola Koszytkowska-Stawińska, Olena Karatsai
Publikováno v:
Bioorganic Chemistry
The 1H-1,2,3-triazole-originated derivatives of willardiine were obtained by: (i) construction of the 1H-1,2,3-triazole ring in 1,3-dipolar cycloaddition of the uracil-derived azides and the carboxylate-bearing alkynes or α-acylphosphorus ylide, or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5292041f05bc8cd05140ad9fbc47edb1
https://pubmed.ncbi.nlm.nih.gov/30453142
https://pubmed.ncbi.nlm.nih.gov/30453142
Publikováno v:
Tetrahedron Letters. 57:199-202
An efficient and highly stereoselective synthesis of bicyclic iminosugars, derivatives of polyhydroxylated decahydropyrido[1,2-a]azepine, was developed. Starting from a two-component coupling reaction, through nitrone formation and a 1,3 dipolar cycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16fd2ef6c74abba3c8cce65f7052ab2b
https://doi.org/10.1016/j.tetlet.2015.11.101
https://doi.org/10.1016/j.tetlet.2015.11.101
Autor:
Ewa Mironiuk-Puchalska, Tomasz Rowicki, Wojciech Sas, Mariola Koszytkowska-Stawińska, Karolina Czerwińska, Maciej Gryszel, Maciej Malinowski, Izabela D. Madura
Publikováno v:
European Journal of Organic Chemistry. 2015:1533-1540
A one-pot, two-step synthesis of chiral 7-oxa-1-azabicyclo[2.2.1]heptane derivatives from unprotected D-xylose was achieved by an intramolecular 1,3-dipolar cycloaddition of the N-(γ-alkenyl)-substituted nitrone intermediate. The stereochemical cour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab9f16764ccc95d79595d20ddd2f59c3
https://doi.org/10.1002/ejoc.201403410
https://doi.org/10.1002/ejoc.201403410
Publikováno v:
Tetrahedron. 68:214-225
2-Substituted-2H-1,2,3-triazolo-nucleosides with 3-phosphonopropyl, 2-hydroxyethyl, 2-cyanoethyl, carbamoylmethyl, or 1-deoxy-2,5-anhydro- d -mannitol-1-yl on the triazole N-2 nitrogen atom were obtained via the DBU-promoted N-alkylation of 3-(pivalo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe60049043fea6d7c230a1a922cb7bce
https://doi.org/10.1016/j.tet.2011.10.067
https://doi.org/10.1016/j.tet.2011.10.067
Publikováno v:
Tetrahedron Letters. 52:1866-1870
Pseudouridine (ψ-uridine, Ψ) aza′-analogues with a 5,5-bis(hydroxymethyl)-1-pyrrolin-2-yl 1-oxide as the glycone mimic were obtained by the addition of (2,4-dimethoxypyrimidin-5-yl)magnesium bromide to 1-aza-7,14-dioxadispiro[4.2.5.2]pentadec-1-e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a32c5153941d1626b0c61e684d3b1a43
https://doi.org/10.1016/j.tetlet.2011.02.018
https://doi.org/10.1016/j.tetlet.2011.02.018
Autor:
Ewa Mironiuk-Puchalska, Yohann Corvis, Beata Korchowiec, Waldemar Priebe, Izabela Fokt, Ewa Rogalska, Mounia Badis, Jacek Korchowiec
Publikováno v:
The Journal of Physical Chemistry B. 112:10953-10963
The two new crown ethers presented in this study were synthesized in order to investigate two important features of ionophores, namely metal cation complexation and interfacial properties, and the way in which they interrelate. The two derivatives we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b97ab7fbcd436d8f4320f8c7452759
https://doi.org/10.1021/jp803072b
https://doi.org/10.1021/jp803072b
Autor:
Ewa Mironiuk-Puchalska, Mariola Koszytkowska-Stawińska, Maciej Gryszel, Izabela D. Madura, Karolina Czerwińska, Tomasz Rowicki, Maciej Malinowski, Wojciech Sas
Publikováno v:
ChemInform. 46
The two-step synthesis of chiral bicyclic products (III) and (IV) involves the conversion of substrate (I) into the corresponding hydroxylamine followed by in situ formation of a chiral nitrone and intramolecular 1,3-dipolar cycloaddition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9db732fa4719d68fc004b42c8aabbccf
https://doi.org/10.1002/chin.201527203
https://doi.org/10.1002/chin.201527203