Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Ewa Kozela"'
Publikováno v:
PLoS Pathogens, Vol 19, Iss 2, p e1011140 (2023)
Extracellular vesicles (EVs) provide a central mechanism of cell-cell communication. While EVs are found in most organisms, their pathogenesis-promoting roles in parasites are of particular interest given the potential for medical insight and consequ
Externí odkaz:
https://doaj.org/article/5b00ffa26228430b83b56c45f8f4ff81
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212039 (2019)
Mammalian microRNAs (miRNAs) play a critical role in modulating the response of immune cells to stimuli. Cannabinoids are known to exert beneficial actions such as neuroprotection and immunosuppressive activities. However, the underlying mechanisms w
Externí odkaz:
https://doaj.org/article/425d080163c34eecbcc0cb6cefa63573
Autor:
Ana Juknat, Maciej Pietr, Ewa Kozela, Neta Rimmerman, Rivka Levy, Fuying Gao, Giovanni Coppola, Daniel Geschwind, Zvi Vogel
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61462 (2013)
Cannabinoids are known to exert immunosuppressive activities. However, the mechanisms which contribute to these effects are unknown. Using lipopolysaccharide (LPS) to activate BV-2 microglial cells, we examined how Δ(9)-tetrahydrocannabinol (THC), t
Externí odkaz:
https://doaj.org/article/910056b1f837493b88f790fd78ef302b
Publikováno v:
Brain, Behavior, and Immunity. 110:185-194
Publikováno v:
Cannabis and Cannabinoid Research.
Autor:
Ayal Ben Zvi, Claudia Pienica, Maayan Aharonian, Hagar Goldenberg, Nofar Schottlender, Lior Naggan, Elad Robinson, Laura Ben Hemo-Cohen, Declan M. McLoughlin, Karen M. Ryan, Hodaya Verdiger, Einat Ashkenazi, Raz Yirmiya, Neta Rimmerman, Lily Ayoun, R. Reshef, Koby Lazar, Ewa Kozela, Ron Refaeli, Eyal Dinur, Sivan Gelb
Publikováno v:
Molecular Psychiatry. 27:1120-1135
Despite evidence implicating microglia in the etiology and pathophysiology of major depression, there is paucity of information regarding the contribution of microglia-dependent molecular pathways to antidepressant procedures. In this study, we inves
Publikováno v:
Brain, Behavior, and Immunity. 106:35-36
Autor:
Elad Robinson, Neta Rimmerman, Hodaya Verdiger, Hagar Goldenberg, Lior Naggan, Ewa Kozela, Sivan Gelb, Ron Refaeli, Eyal Dinur, Ayal Ben Zvi, Raz Yirmiya
Publikováno v:
Brain, Behavior, and Immunity. 106:25
Publikováno v:
Molecular neurobiology. 57(3)
Cannabidiol (CBD), a non-psychotropic cannabinoid, demonstrates antipsychotic-like and procognitive activities in humans and in animal models of schizophrenia. The mechanisms of these beneficial effects of CBD are unknown. Here, we examined behaviora
Publikováno v:
Journal of Basic and Clinical Physiology and Pharmacology. 27:289-296
Background: Dimethylheptyl-cannabidiol (DMH-CBD), a non-psychoactive, synthetic derivative of the phytocannabinoid cannabidiol (CBD), has been reported to be anti-inflammatory in RAW macrophages. Here, we evaluated the effects of DMH-CBD at the trans