Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ewa Kilar"'
Autor:
Milena Matuszczak, Adam Kiljańczyk, Wojciech Marciniak, Róża Derkacz, Klaudia Stempa, Piotr Baszuk, Marta Bryśkiewicz, Cezary Cybulski, Tadeusz Dębniak, Gronwald Jacek, Tomasz Huzarski, Marcin Lener, Anna Jakubowska, Sandra Pietrzak, Marek Szwiec, Małgorzata Stawicka-Niełacna, Dariusz Godlewski, Artur Prusaczyk, Andrzej Jasiewicz, Tomasz Kluz, Joanna Tomiczek-Szwiec, Ewa Kilar-Kobierzycka, Monika Siołek, Renata Posmyk, Joanna Jarkiewicz-Tretyn, Rodney Scott, Steven Narod, Jan Lubiński
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 22, Iss 1, Pp 1-7 (2024)
Abstract Objective To investigate whether Molybdenum blood level is a marker of cancer risk on BRCA1 carriers. Methods A prospective cohort study was conducted among 989 initially unaffected women with a BRCA1 mutation. Blood samples were collected t
Externí odkaz:
https://doaj.org/article/7c7994beee88433aa6b35d2b8a487a7c
Autor:
Milena Matuszczak, Adam Kiljańczyk, Wojciech Marciniak, Róża Derkacz, Klaudia Stempa, Piotr Baszuk, Marta Bryśkiewicz, Cezary Cybulski, Tadeusz Dębniak, Jacek Gronwald, Tomasz Huzarski, Marcin Lener, Anna Jakubowska, Marek Szwiec, Małgorzata Stawicka-Niełacna, Dariusz Godlewski, Artur Prusaczyk, Andrzej Jasiewicz, Tomasz Kluz, Joanna Tomiczek-Szwiec, Ewa Kilar-Kobierzycka, Monika Siołek, Rafał Wiśniowski, Renata Posmyk, Joanna Jarkiewicz-Tretyn, Rodney Scott, Jan Lubiński
Publikováno v:
Antioxidants, Vol 13, Iss 7, p 841 (2024)
Pathogenic mutations in BRCA1 (BReast CAncer gene 1) confer high risks of both breast (up to 70%) and ovarian (up to 40%) cancers. Zinc (Zn) and copper (Cu) are essential for various physiological functions, including antioxidant reactions. Their bal
Externí odkaz:
https://doaj.org/article/b53107c2804a4ba692f220cede196a1b
Autor:
Milena Matuszczak, Adam Kiljańczyk, Wojciech Marciniak, Róża Derkacz, Klaudia Stempa, Piotr Baszuk, Marta Bryśkiewicz, Ping Sun, Angela Cheriyan, Cezary Cybulski, Tadeusz Dębniak, Jacek Gronwald, Tomasz Huzarski, Marcin R. Lener, Anna Jakubowska, Marek Szwiec, Małgorzata Stawicka-Niełacna, Dariusz Godlewski, Artur Prusaczyk, Andrzej Jasiewicz, Tomasz Kluz, Joanna Tomiczek-Szwiec, Ewa Kilar-Kobierzycka, Monika Siołek, Rafał Wiśniowski, Renata Posmyk, Joanna Jarkiewicz-Tretyn, Rodney J. Scott, Steven A. Narod, Jan Lubiński
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 609 (2024)
BRCA1 mutations predispose women to breast and ovarian cancer. The anticancer effect of zinc is typically linked to its antioxidant abilities and protecting cells against oxidative stress. Zinc regulates key processes in cancer development, including
Externí odkaz:
https://doaj.org/article/e5dfa70e55534b1486d9936a12131407
Autor:
Joanna Tomiczek-Szwiec, Marek Szwiec, Michał Falco, Cezary Cybulski, Dominika Wokolorczyk, Anna Jakubowska, Jacek Gronwald, Małgorzata Stawicka, Dariusz Godlewski, Ewa Kilar, Elżbieta Marczyk, Monika Siołek, Rafał Wiśniowski, Olga Haus, Robert Sibilski, Lubomir Bodnar, Ping Sun, Steven A Narod, Jan Lubinski, Tomasz Huzarski
Publikováno v:
Diagnostics.
Autor:
Anna Janocha, Teresa Skiba, Ewa Kilar, Jakub Gburek, Maciej Siewinski, Krzysztof Gołab, Lidia Hirnle, Marek Murawski
Publikováno v:
Cancer Biomarkers. 27:335-341
BACKGROUND The key role in carcinogenesis with destruction of the extracellular matrix is played by proteases released by invasive cancer cells. Cysteine peptidases, such as cathepsin B and L, take an important role in cancer progression and metastas
Autor:
Maciej, Siewiński, Barbara, Bażanów, Beata, Orzechowska, Krzysztof, Gołąb, Jakub, Gburek, Adam, Matkowski, Andrzej, Rapak, Anna, Janocha, Lechosław, Krata, Maciej, Dobrzyński, Ewa, Kilar
Publikováno v:
Medical Hypotheses. 168:110965
Specific antibodies that humans acquire as a result of disease or after vaccination are needed to effectively suppress infection with a specific variant of SARS CoV-2 virus. The S protein of the D614G variant of coronavirus is used as an antigen in k
Autor:
Marek Murawski, Anna Janocha, Lidia Hirnle, Maciej Siewinski, Teresa Skiba, Jakub Gburek, Krzysztof Gołąb, Ewa Kilar
Publikováno v:
Advances in clinical and experimental medicine : official organ Wroclaw Medical University. 30(3)
Background The activity of autogenic proteolytic enzymes is regulated in vivo by autogenic inhibitors. They play important roles in maintaining a balance in many processes in the human body. In pathological conditions, enzymes are overexpressed and t
Autor:
Bohdan Gworys, Ewa Kilar, Jakub Gburek, Teresa Skiba, Krzysztof Gołąb, Anna Janocha, Maciej Siewinski
Publikováno v:
Cancer Biomarkers. 15:99-102
Background Complement information about the share the role of antipapain activity in serum people with breast cancer. Objective We measured the activity of cysteine peptidase inhibitors in the sera of 150 patients with breast cancer. Patients were di
Autor:
Tomasz, Huzarski, Barbara, Górecka-Szyld, Jowita, Huzarska, Grażyna, Psut-Muszyńska, Grażyna, Wilk, Robert, Sibilski, Cezary, Cybulski, Beata, Kozak-Klonowska, Monika, Siołek, Ewa, Kilar, Dorota, Czudowska, Hanna, Janiszewska, Dariusz, Godlewski, Andrzej, Mackiewicz, Joanna, Jarkiewicz-Tretyn, Jadwiga, Szabo-Moskal, Jacek, Gronwald, Jan, Lubiński, Steven A, Narod, P, Sosnowski
Publikováno v:
Hereditary Cancer in Clinical Practice
Background The addition of MRI to mammography and ultrasound for breast cancer screening has been shown to improve screening sensitivity for high risk women, but there is little data to date for women at average or intermediate risk. Methods Two thou
Autor:
Andres Garcia, Palomo, Iwona, Glogowska, Harald, Sommer, Nikolaos, Malamos, Ewa, Kilar, Jose M Lopez, Vega, Laura, Torrecillas, Thierry, Delozier, Johannes, Ettl, Jindrich, Finek
Publikováno v:
Anticancer research. 32(10)
Full oral chemotherapy (CT) is an active and convenient therapeutic option for patients with advanced breast cancer (ABC). In this retrospective analysis, we reviewed the characteristics and the outcome of patients treated by oral vinorelbine either