Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Ewa Jankowska-Gan"'
Autor:
William J. Burlingham, PhD, Ewa Jankowska-Gan, MS, John H. Fechner, MS, Christopher J. Little, MD, Jianxin Wang, PhD, Seungpyo Hong, PhD, Miraf Molla, BS, Jeremy A. Sullivan, PhD, David P. Foley, MD
Publikováno v:
Transplantation Direct, Vol 9, Iss 6, p e1475 (2023)
Background. Here we test the hypothesis that, like CD81-associated “latent” IL35, the transforming growth factor (TGF)β:latency-associated peptide (LAP)/glycoprotein A repetitions predominant (GARP) complex was also tethered to small extracellul
Externí odkaz:
https://doaj.org/article/55c62bbd8b1e4c159f6be1fe92b81bef
Donor HLA−DR Drives the Development of De Novo Autoimmunity Following Lung and Heart Transplantation
Autor:
Ewa Jankowska−Gan, MS, Vrushali V. Agashe, PhD, Diego A. Lema, MD, Ying Zhou, MS, Laura Gonzalez Bosc, PhD, Jeremy A. Sullivan, PhD, Daniel S. Greenspan, PhD, William J. Burlingham, PhD
Publikováno v:
Transplantation Direct, Vol 6, Iss 10, p e607 (2020)
Background. Individuals harbor preexisting HLA−DR/DQ−restricted responses to collagen type V (ColV) mediated by Th17 cells under Treg control, both specific to peptides that bind to inherited HLA class II antigens. Yet after transplant, the donor
Externí odkaz:
https://doaj.org/article/440bd605fad843e1bb8e3d2b1e36fbab
Autor:
Jeremy A. Sullivan, Yusuke Tomita, Ewa Jankowska-Gan, Diego A. Lema, Matt P. Arvedson, Ashita Nair, William Bracamonte-Baran, Ying Zhou, Kristy K. Meyer, Weixiong Zhong, Deepali V. Sawant, Andrea L. Szymczak-Workman, Qianxia Zhang, Creg J. Workman, Seungpyo Hong, Dario A.A. Vignali, William J. Burlingham
Publikováno v:
Cell Reports, Vol 30, Iss 4, Pp 1039-1051.e5 (2020)
Summary: Interleukin-35 (IL-35) is an immunosuppressive cytokine composed of Epstein-Barr-virus-induced protein 3 (Ebi3) and IL-12α chain (p35) subunits, yet the forms that IL-35 assume and its role in peripheral tolerance remain elusive. We induce
Externí odkaz:
https://doaj.org/article/19bc2a5483074d60bb874b0ead25e86d
Autor:
Diego A. Lema, Ewa Jankowska-Gan, Ashita Nair, Sami B. Kanaan, Christopher J. Little, David P. Foley, Afsar Raza Naqvi, Jianxin Wang, Seungpyo Hong, J. Lee Nelson, David Al-Adra, William J. Burlingham, Jeremy A. Sullivan
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 22(5)
Exposure to non-inherited maternal antigens (NIMA) during the fetal period induces lifelong split tolerance to grafts expressing these allo-antigens. In adult mice, the production of extracellular vesicles (EVs) from maternal microchimeric cells caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65073b17ef81b499727af95114a73a0d
https://pubmed.ncbi.nlm.nih.gov/35143105
https://pubmed.ncbi.nlm.nih.gov/35143105
Autor:
Miranda P Dierselhuis, Ewa Jankowska-Gan, Els Blokland, Jos Pool, William J Burlingham, Astrid G S van Halteren, Els Goulmy
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91274 (2014)
Sex difference is an established risk factor for hematopoietic stem cell transplantation (HSCT)-related complications like graft versus host disease (GVHD). CD8pos cytotoxic T cells specific for Y chromosome-encoded minor Histocompatibility antigens
Externí odkaz:
https://doaj.org/article/014d146200644273897296edba74785e
Autor:
Melissa R Keller, Lynn D Haynes, Ewa Jankowska-Gan, Jeremy A Sullivan, Vrushali V Agashe, Scott R Burlingham, William J Burlingham
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79601 (2013)
IL-17-dependent cellular immune responses to the α1 chain of collagen type V are associated with development of bronchiolitis obliterans syndrome after lung transplantation, and with idiopathic pulmonary fibrosis and coronary artery disease, primary
Externí odkaz:
https://doaj.org/article/897a43cab5a3419ab3128aef1ce463f0
Autor:
Thomas C. Resta, Levi D. Maston, Jeremy A. Sullivan, Benjamin J Lantz, Nancy L. Kanagy, Tamara Howard, Joshua R. Sheak, Micaela M Resta, Danielle Vigil, David T Jones, Rudolf K. Braun, William J. Burlingham, Yan Guo, Ewa Jankowska-Gan, Laura V. Gonzalez Bosc
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Chronic hypoxia (CH)-induced pulmonary hypertension (PH) results, in part, from T helper-17 (TH17) cell-mediated perivascular inflammation. However, the antigen(s) involved is unknown. Cellular immunity to collagen type V (col V) develops after ische
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b5f0687400f1b7bcb1009013139457
https://europepmc.org/articles/PMC7792682/
https://europepmc.org/articles/PMC7792682/
Donor HLA−DR Drives the Development of De Novo Autoimmunity Following Lung and Heart Transplantation
Autor:
Jeremy A. Sullivan, Diego A Lema, Laura V. Gonzalez Bosc, Ewa Jankowska Gan, Ying Zhou, Daniel S. Greenspan, Vrushali V. Agashe, William J. Burlingham
Publikováno v:
Transplantation Direct
Transplantation Direct, Vol 6, Iss 10, p e607 (2020)
Transplantation Direct, Vol 6, Iss 10, p e607 (2020)
Background. Individuals harbor preexisting HLA−DR/DQ−restricted responses to collagen type V (ColV) mediated by Th17 cells under Treg control, both specific to peptides that bind to inherited HLA class II antigens. Yet after transplant, the donor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66de25560477f0d999bc9b18a8520861
http://europepmc.org/articles/PMC7515617
http://europepmc.org/articles/PMC7515617
Autor:
Tiffany Zens, Anthony M. D’Alessandro, Michael J. Eerhart, Peter J. Chlebeck, Jose A. Reyes, Saverio Capuano, Daniel Burguete, Yucel Yankol, Yolanda Ponstein, Luis A. Fernandez, Jose R. Torrealba, Jennifer Coonen, William J. Burlingham, Kevin Brunner, Laura J. Zitur, Edwin Van Amersfoort, Myron A. Pozniak, Jeremy A. Sullivan, Juan S. Danobeitia, Arjang Djamali, Ewa Jankowska-Gan, Cees van Kooten
Publikováno v:
American Journal of Transplantation, 20(6), 1513-1526. WILEY
Delayed graft function (DGF) in renal transplant is associated with reduced graft survival and increased immunogenicity. The complement-driven inflammatory response after brain death (BD) and posttransplant reperfusion injury play significant roles i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b7a7a020e6c0b5601705b12f0a6b72
https://hdl.handle.net/1887/3185005
https://hdl.handle.net/1887/3185005
Autor:
Jeremy A. Sullivan, Ewa Jankowska-Gan, Jose R. Torrealba, Vrushali V. Agashe, David S. Wilkes, William J. Burlingham, Melissa R. Keller, Melanie Dart, Drew A. Roenneburg, Marco Colonna, Lynn D. Haynes, John F. Kernien
Publikováno v:
The Journal of Immunology. 201:772-781
Leukocyte-associated Ig-like receptor 1 (LAIR1) is an ITIM-bearing collagen receptor expressed by leukocytes and is implicated in immune suppression. However, using a divalent soluble LAIR1/Fc recombinant protein to block interaction of cell surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bdc5656fb0f4b547be303fa79a334cb
https://doi.org/10.4049/jimmunol.1701753
https://doi.org/10.4049/jimmunol.1701753