Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ewa Gruszecka-Kowalik"'
Autor:
Scott J. Myers, Phuong Le, Raymond Dingledine, Dennis C. Liotta, Hasan A. Irier, Adam French, Matthew T. Geballe, Yesim Altas Tahirovic, Robert Kotloski, Ewa Gruszecka-Kowalik, Woo-Baeg Choi, Hongjie Yuan, Lawrence J. Wilson, Stephen F. Traynelis, Polina Lyuboslavsky, James O. McNamara, James P. Snyder, Keith W Easterling
Publikováno v:
Journal of Medicinal Chemistry. 51:5506-5521
Enantiomeric propanolamines have been identified as a new class of NR2B-selective NMDA receptor antagonists. The most effective agents are biaryl structures, synthesized in six steps with overall yields ranging from 11-64%. The compounds are potent a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::873377656192885b3c6bec2d946da06f
https://doi.org/10.1021/jm8002153
https://doi.org/10.1021/jm8002153
Autor:
Leon H. Zalkow, Ewa Gruszecka-Kowalik
Publikováno v:
Organic Preparations and Procedures International. 32:57-61
(2000). AN IMPROVED SYNTHESIS OF HYPERICIN AND RELATED COMPOUNDS. Organic Preparations and Procedures International: Vol. 32, No. 1, pp. 57-61.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a7c4476f1a5c45229523acb6978b5fd
https://doi.org/10.1080/00304940009356746
https://doi.org/10.1080/00304940009356746
Publikováno v:
Journal of Chemical Crystallography. 30:291-299
Two epimers of 20-aminopregn-5-en-3β-ol differing in configuration at C(20) have been synthesized and their structures have been determined by single crystal X-ray diffraction methods. The (20R)-epimer (1) crystallized in the orthorhombic system, sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd98c390f700bdda2feabba8cef951e2
https://doi.org/10.1023/a:1009553022723
https://doi.org/10.1023/a:1009553022723
Autor:
Qing Shi, Howard M. Deutsch, Milind Misra, Xiaocong Ye, Carol A. Venanzi, Zhanzhu Liu, Margaret M. Schweri, Wei Bu, Ewa Gruszecka-Kowalik
Publikováno v:
Bioorganicmedicinal chemistry. 18(20)
Complementary two-dimensional (2D) and three-dimensional (3D) Quantitative Structure–Activity Relationship (QSAR) techniques were used to derive a preliminary model for the dopamine transporter (DAT) binding affinity of 80 racemic threo-methylpheni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333782933edd836f716cacdb17bab99a
https://pubmed.ncbi.nlm.nih.gov/20846865
https://pubmed.ncbi.nlm.nih.gov/20846865
Autor:
Leon H. Zalkow, Ewa Gruszecka-Kowalik
Publikováno v:
ChemInform. 31
(2000). AN IMPROVED SYNTHESIS OF HYPERICIN AND RELATED COMPOUNDS. Organic Preparations and Procedures International: Vol. 32, No. 1, pp. 57-61.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::810e8c8da4de29980c7c9bd8783413af
https://doi.org/10.1002/chin.200026231
https://doi.org/10.1002/chin.200026231
Publikováno v:
Biochemical and Biophysical Research Communications. 187:1409-1417
A simple synthesis of the sulfonated azo dye Quinobene ( 3 ) and its derivatives, as well as the results of their evaluation in anti-HIV screening have been described. Thus, reacting the diazonium salt of 4,4′-diaminostilbene-2,2′-disulfonic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578ccf3711101cf4be7151a90abd699c
https://doi.org/10.1016/0006-291x(92)90459-x
https://doi.org/10.1016/0006-291x(92)90459-x
Autor:
Ewa Gruszecka-Kowalik, Leon H. Zalkow
Publikováno v:
The Journal of Organic Chemistry. 55:3398-3403
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddff861e1e8a33ddf8933a77e4d8de9a
https://doi.org/10.1021/jo00297a081
https://doi.org/10.1021/jo00297a081
Publikováno v:
Journal of medicinal chemistry. 39(6)
As part of a program to develop medications which can block the binding of cocaine to the dopamine transporter, yet spare dopamine uptake, a series of aromatic ring-substituted methylphenidate derivatives was synthesized and tested for inhibitory pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3186106e8d556aa9a724f7499f30faa
https://pubmed.ncbi.nlm.nih.gov/8632426
https://pubmed.ncbi.nlm.nih.gov/8632426
Autor:
Yesim A. Tahirovic, Matthew Geballe, Ewa Gruszecka-Kowalik, Scott J. Myers, Polina Lyuboslavsky, Phuong Le, Adam French, Hasan Irier, Woo-baeg Choi, Keith Easterling, Hongjie Yuan, Lawrence J. Wilson, Robert Kotloski, James O. McNamara, Raymond Dingledine, Dennis C. Liotta, Stephen F. Traynelis, James P. Snyder
Publikováno v:
Journal of Medicinal Chemistry; Aug2008, Vol. 51 Issue 18, p5506-5521, 16p