Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ewa Ciszak"'
Publikováno v:
International Journal of Peptide and Protein Research. 39:218-222
The crystal structure of Ac-Pro-delta Val-NHCH3 was examined to determine the influence of the alpha,beta-dehydrovaline residue on the nature of peptide conformation. The peptide crystallizes from methanol-diethyl ether solution at 4 degrees in needl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ed2dc948b35043330c5f0e1ee8b4ced
https://doi.org/10.1111/j.1399-3011.1992.tb00792.x
https://doi.org/10.1111/j.1399-3011.1992.tb00792.x
Publikováno v:
Nucleic Acids Research
Creating endonucleases with novel sequence specificities provides more possibilities to manipulate DNA. We have created a chimeric endonuclease (CH-endonuclease) consisting of the DNA cleavage domain of BmrI restriction endonuclease and C.BclI, a con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75dd4b1cde1368fbe356da2a7f6ff564
https://doi.org/10.1093/nar/gkm665
https://doi.org/10.1093/nar/gkm665
Autor:
Ralph Golbik, Paulina M. Dominiak, Franziska Seifert, Michael Spinka, Kai Tittmann, Mulchand S. Patel, Ewa Ciszak, Lioubov G. Korotchkina, Johanna Brauer, Sukhdeep Sidhu
Publikováno v:
Biochemistry. 46:6277-6287
At the junction of glycolysis and the Krebs cycle in cellular metabolism, the pyruvate dehydrogenase multienzyme complex (PDHc) catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA. In mammals, PDHc is tightly regulated by phosphorylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e3261ec7a8cf5e51355d7ec8a94387
https://doi.org/10.1021/bi700083z
https://doi.org/10.1021/bi700083z
Publikováno v:
Journal of Peptide Science. 12:538-549
The crystal structures of two diastereomeric alpha,beta-dehydrobutyrine peptides Ac-Pro-(Z)-DeltaAbu-NHMe (I) and Ac-Pro-(E)-DeltaAbu-NHMe (II) have been determined. Both dehydropeptides adopt betaI-turn conformation characterized by the pairs of (ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09cd498f18849c099517fa810a61913b
https://doi.org/10.1002/psc.763
https://doi.org/10.1002/psc.763
Publikováno v:
Archives of Biochemistry and Biophysics. 429:171-179
Pyruvate dehydrogenase (E1), an alpha 2 beta 2 tetramer, catalyzes the oxidative decarboxylation of pyruvate and reductive acetylation of lipoyl moieties of the dihydrolipoamide acetyltransferase. The roles of beta W135, alpha P188, alpha M181, alpha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b459c343486f5d7ad3e86fdbc4b7f8bc
https://doi.org/10.1016/j.abb.2004.06.027
https://doi.org/10.1016/j.abb.2004.06.027
Publikováno v:
Journal of Biological Chemistry. 279:33992-33999
Serine/threonine protein phosphatase-5 (PP5) affects many signaling networks that regulate cell growth and cellular responses to stress. Here we report the crystal structure of the PP5 catalytic domain (PP5c) at a resolution of 1.6 A. From this struc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cfe1470c09f88abf5a86d0e6a414ffb
https://doi.org/10.1074/jbc.m402855200
https://doi.org/10.1074/jbc.m402855200
Publikováno v:
Journal of Biological Chemistry. 278:21240-21246
Thiamin pyrophosphate (TPP), the biologically active form of vitamin BI, is a cofactor of enzymes catalyzing reactions involving the cleavage of a carbon-carbon bond adjacent to an oxo group. TPP-dependent enzymes show a common mechanism of TPP activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f97ffb441037a174aeb5f58266710e
https://doi.org/10.1074/jbc.m300339200
https://doi.org/10.1074/jbc.m300339200
Publikováno v:
Journal of Applied Crystallography. 33:882-887
The design and performance of a high-flux X-ray crystallography system, optimized for diffraction measurements from small macromolecular crystals, is described. This system combines a microfocus X-ray generator [40 µm full width at half-maximum (FWH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::425677d0e7445759be8946a25edfe9be
https://doi.org/10.1107/s0021889800001837
https://doi.org/10.1107/s0021889800001837
Publikováno v:
Proceedings of the National Academy of Sciences. 89:6644-6648
The crystal structure of the complex of 3',5'-dibromo-2',4,4',6-tetrahydroxyaurone, a flavone derivative, with human transthyretin (TTR), a serum thyroid hormone transport protein, has been determined and refined to R = 17.9% for data to 2.3-A resolu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de72e82135aeee49c0013826e01c33bd
https://doi.org/10.1073/pnas.89.14.6644
https://doi.org/10.1073/pnas.89.14.6644
Publikováno v:
Journal of Molecular Structure: THEOCHEM. 251:345-357
The crystal and molecular structures of (Z)-4,4',6-triacetoxy aurone ( I ) and (Z)-3',5'-di-bromo-2',4,4',6-tetrahydroxyaurone monohydrate ( II ) have been studied by X-ray analysis and AM1 molecular orbital methods. Aurones are characterized by a me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::981a2cb4c2232ef26d5ade5adcdee90b
https://doi.org/10.1016/0166-1280(91)85157-3
https://doi.org/10.1016/0166-1280(91)85157-3