Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ewa Anna Dabrowska"'
Publikováno v:
European Journal of Pharmaceutical Sciences. 12:175-179
Few drugs have been successfully formulated as submicron emulsions. The physicochemical stability of submicron emulsions on admixture of drugs is the main factor limiting a wider use of this type of vehicle for parenteral or other routes of administr
Publikováno v:
International Journal of Pharmaceutics. 202:161-164
Submicron emulsions containing pilocarpine as ion-pair with mono-dodecylphosphoric acid were prepared. Physical stability of these preparations was confirmed during 4 months of storage at 4 degrees C. Approximately 50% of the drug was found in the aq
Autor:
Ewa Anna Dabrowska, Malgorzata Bodnar, Helena Janik, Małgorzata Sznitowska, Jacek Petrusewicz
Publikováno v:
Journal of microencapsulation. 26(7)
Amorphous paclitaxel dissolves rapidly (1 mg mL(-1)) in an isotonic aqueous dispersion of egg lecithin (5% w/w), a new biocompatible submicron drug carrier consisting of structured aggregates with average size 0.5 microm. The solution is physically s
Publikováno v:
International journal of pharmaceutics. 246(1-2)
Aqueous lecithin dispersions (WLD, water-lecithin-dispersion) were obtained by dispersing egg lecithin (1.2 or 2.4% w/w) in an isotonic mixture of glycerol and water. The solubilization potential of the pure phospholipid structures was investigated a
Physicochemical screening of antimicrobial agents as potential preservatives for submicron emulsions
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 15(5)
Antimicrobial agents should be added to lecithin-stabilized submicron emulsions when these preparations are non-sterile products or when packed in multidose containers. Eleven antimicrobials were introduced to a standard submicron emulsion. The emuls