Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Evyn J Loucks"'
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14396 (2010)
The Hedgehog (Hh)-signaling pathway plays a crucial role in the development and maintenance of multiple vertebrate and invertebrate organ systems. Gli transcription factors are regulated by Hh-signaling and act as downstream effectors of the pathway
Externí odkaz:
https://doaj.org/article/32bbad599ad24d9086f7da930d6230ef
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 7, Pp 1328-1344 (2011)
Abstract Niemann-Pick disease, type C (NP-C), often associated with Niemann-Pick disease, type C1 (NPC1) mutations, is a cholesterol-storage disorder characterized by cellular lipid accumulation, neurodegeneration, and reduced steroid production. T
Externí odkaz:
https://doaj.org/article/82721fa136b34df8b333e238eb86a655
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 7, Pp 1328-1344 (2011)
Niemann-Pick disease, type C (NP-C), often associated with Niemann-Pick disease, type C1 (NPC1) mutations, is a cholesterol-storage disorder characterized by cellular lipid accumulation, neurodegeneration, and reduced steroid production. To study N
Autor:
Evyn J. Loucks, Sara C. Ahlgren
Publikováno v:
Birth Defects Research Part A: Clinical and Molecular Teratology. 85:556-567
BACKGROUND: The phenotype of embryos exposed to ethanol is complex and likely due to multiple alterations in developmental pathways. We have previously demonstrated that Sonic hedgehog signaling (Shh-s) was reduced in both chicken and zebrafish embry
Autor:
Michael J. Carvan, Evyn J. Loucks
Publikováno v:
Neurotoxicology and Teratology. 26:745-755
Developmental ethanol exposure from maternal consumption of alcoholic beverages and many other consumer products has been linked to developmental abnormalities in humans and animal models. The sensitivity of an individual to ethanol-induced perturbat
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 12, p e14396 (2010)
PLoS ONE, Vol 5, Iss 12, p e14396 (2010)
Background The Hedgehog (Hh)-signaling pathway plays a crucial role in the development and maintenance of multiple vertebrate and invertebrate organ systems. Gli transcription factors are regulated by Hh-signaling and act as downstream effectors of t
Publikováno v:
Birth defects research. Part A, Clinical and molecular teratology. 79(9)
BACKGROUND: Exposure of zebrafish embryos to a number of teratogens results in cyclopia, but little is known about the underlying molecular changes. METHODS: Using zebrafish embryos, we compare the effects cyclopamine, forskolin, and ethanol delivere
Autor:
Sara C. Ahlgren, Evyn J. Loucks
Publikováno v:
Developmental Biology.
Publikováno v:
Neurotoxicology and teratology. 26(6)
Exposure to ethanol during development can lead to a constellation of congenital anomalies, resulting in prenatal and postnatal failure to thrive, central nervous system (CNS) deficits, and a number of patterning defects that lead to defects in the c
Autor:
Evyn J. Loucks, Sara C. Ahlgren
Publikováno v:
Developmental Biology. 306:409