Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Evsey A. Ruchko"'
Autor:
Dmitry S. Sheikin, Evgeniya S. Titova, Evsey А. Ruchko, Maxim B. Nawrozkij, Anastasiya Kotlyarova, Ivan А. Novakov, Leila L. Brunilina, Tatyana G. Tolstikova, Alla Pavlova, Ivan А. Kirillov, Mariya D. Robinovich
Publikováno v:
Chemistry of Heterocyclic Compounds. 56:769-775
New structural analogs of 3-phenacyluridine were obtained as a result of N(3)-alkylation of 1-(2-acetoxyethyl)- and 1-(2-acetoxyethoxymethyl) uracil. Biological studies of the title compounds in an acute in vivo experiment did not reveal their hypnot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68e5ee45cdbddeec9fd54fcb5b6ca7cb
https://doi.org/10.1007/s10593-020-02729-x
https://doi.org/10.1007/s10593-020-02729-x
Autor:
Dmitry S. Sheikin, A. Yu. Maryshev, A. S. Babushkin, Dominique Schols, V. V. Chapurkin, Ivan A. Novakov, M. B. Navrotskii, Evsey A. Ruchko
Publikováno v:
Russian Journal of General Chemistry. 90:352-356
The Tscherniac–Einhorn reaction of 6-methyl and 6-(trifluoromethyl) derivatives of 2-thiouracil with N-(bromomethyl)phthalimide in under basic catalysis leads to the formation of S-amidomethylation products. When using 6-amino-2-thiouracil, decompo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34fc8faa527b35aafc0cca4c05f1ae52
https://doi.org/10.1134/s1070363220030056
https://doi.org/10.1134/s1070363220030056
Autor:
Evsey A. Ruchko, Vladimir Egorovich Fedorov, Anton Vladimirovich Omelkov, Pharm-Synthesis\\', Jsc \\'Pharm-Synthesis\\'
Publikováno v:
Butlerov Communications. 61:21-32
The discovery in 2002 among derivatives of 6-bromo-3-benzyl-2-methoxyquinolines the highly active compounds against M. Tuberculosis bacterium and its drug-resistant strains led to the creation of the innovative anti-TB drug TMS-207 in 2013 by Janssen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b9988b0d5b1dc7a83e67ad12ba4a616
https://doi.org/10.37952/roi-jbc-01/20-61-1-21
https://doi.org/10.37952/roi-jbc-01/20-61-1-21
Autor:
Anton Yu. Maryshev, Viktor V. Chapurkin, Dmitry S. Sheikin, Dominique Schols, Yaroslav P. Kuznetsov, Maksim B. Nawrozkij, Ivan A. Novakov, Alexande S. Babushkin, Evsey A. Ruchko, Vadim V. Kachala
Publikováno v:
Chemistry of Heterocyclic Compounds. 56:67-72
The interaction of N-(2-bromoethyl)- and N-(3-bromopropyl)phthalimides with 2-thiouracils substituted at position 6 was studied in alkaline medium, providing S-monoamidoalkylation products and, depending on the substituents, the products of S,O(4)- a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d70680cd0ce8d00bc8339a6c025bce50
https://doi.org/10.1007/s10593-020-02624-5
https://doi.org/10.1007/s10593-020-02624-5
Autor:
L. L. Brunilina, V. V. Chapurkin, Evsey A. Ruchko, Dmitry S. Sheikin, Dominique Schols, Y. P. Kuznetsov, I. A. Novakov, M. B. Nawrozkij
Publikováno v:
AIP Conference Proceedings.
Synthesis of the novel Isothiobarbamine analogues with lowered basicity has been prepared. The peculiarities of their synthesis and preliminary data on their biological activity are presented.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3525f32b22ee9567f6113e93580b6b7b
https://doi.org/10.1063/5.0018050
https://doi.org/10.1063/5.0018050
Autor:
Maksim B. Nawrozkij, Alexandre S. Babushkin, Vadim V. Kachala, Dominique Schols, Sergey N. Lavrenov, Evsey A. Ruchko
Publikováno v:
Chemistry of Heterocyclic Compounds. 51:978-983
We report new carboanalogs of umifenovir – regioisomeric derivatives of ethyl 5-hydroxy-(trans-2-phenylcyclopropyl)-1Н-indole-3-carboxylate. The inhibition of HIV replication by umifenovir and its carboanalogs at micromolar concentration range has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7753437ebd356636a897c401f23b0e07
https://doi.org/10.1007/s10593-016-1807-9
https://doi.org/10.1007/s10593-016-1807-9
Autor:
Ivan A. Novakov, M. B. Nawrozkij, V. N. Charushin, Evgeniy B. Gorbunov, G. L. Rusinov, Alexandre S. Babushkin, Evsey A. Ruchko
Publikováno v:
Macroheterocycles
A convenient way to 1-(pyridin-2-yl)ethan-1,2-diol, 2-(oxiran-2-yl)pyridine and two diastereomeric forms of 1-(piperidin-2-yl)ethan-1,2-diol, valuable building-blocks for the synthesis of functionalized crown ethers, has been developed. It is based o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a0aacaab5dd35d42e5724838a14ba9f
http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=84926241810
http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=84926241810
Autor:
Novakov, Ivan A.1 (AUTHOR), Sheikin, Dmitry S.1 (AUTHOR) d.sheikin@yandex.ru, Chapurkin, Viktor V.1 (AUTHOR), Nawrozkij, Maksim B.1 (AUTHOR), Babushkin, Alexande S.1 (AUTHOR), Kuznetsov, Yaroslav P.2 (AUTHOR), Ruchko, Evsey A.3 (AUTHOR), Kachala, Vadim V.4 (AUTHOR), Maryshev, Anton Yu.5 (AUTHOR), Schols, Dominique6 (AUTHOR)
Publikováno v:
Chemistry of Heterocyclic Compounds. 2020, Vol. 56 Issue 1, p67-72. 6p. 3 Diagrams, 1 Chart.