Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Evolutionary trace"'
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 21, Iss 6, Pp 1182-1194 (2023)
Exploring the natural diversity of functional genes/proteins from environmental DNA in high throughput remains challenging. In this study, we developed a sequence-based functional metagenomics procedure for mining the diversity of copper (Cu) resista
Externí odkaz:
https://doaj.org/article/02c13788c0344fb094ddc807c6806d7a
Autor:
Jie Zhu, Feng Yang, Kang Du, Zi-Lu Wei, Qing-Fa Wu, Yuxing Chen, Wei-Fang Li, Qiong Li, Cong-Zhao Zhou
Publikováno v:
Environmental Microbiome, Vol 18, Iss 1, Pp 1-15 (2023)
Abstract Background Along with the fast development and urbanization in developing countries, the waterbodies aside the growing cities become heavily polluted and highly eutrophic, thus leading to the seasonal outbreak of cyanobacterial bloom. System
Externí odkaz:
https://doaj.org/article/a6bbcaa5725d4d1b95df4ee3154fe804
Autor:
Isabel Cea-Rama, Cristina Coscolín, Panagiotis Katsonis, Rafael Bargiela, Peter N. Golyshin, Olivier Lichtarge, Manuel Ferrer, Julia Sanz-Aparicio
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 2307-2317 (2021)
Our understanding of enzymes with high substrate ambiguity remains limited because their large active sites allow substrate docking freedom to an extent that seems incompatible with stereospecificity. One possibility is that some of these enzymes evo
Externí odkaz:
https://doaj.org/article/844d132af0594375aaa023eb27a62377
Autor:
Yingchen Wang, Zhe Zhang, Lei Shang, Hong Gao, Xiqiao Du, Falong Li, Ya Gao, Guiyun Qi, Weiyuan Guo, Zhangyi Qu, Tuo Dong
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Aim: To reconstruct the ancestral sequence of human adenoviral hexon protein by combining sequence variations and structural information. And to provide a candidate hexon protein for developing new adenoviral vector capable of escaping the pre-existi
Externí odkaz:
https://doaj.org/article/a32cca786c3c4eee9bde4a2871a07345
Akademický článek
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Publikováno v:
Biomolecules, Vol 12, Iss 1, p 59 (2021)
Group I chaperonins are a highly conserved family of essential proteins that self-assemble into molecular nanoboxes that mediate the folding of cytoplasmic proteins in bacteria and organelles. GroEL, the chaperonin of Escherichia coli, is the archety
Externí odkaz:
https://doaj.org/article/5f4b02a398a541d98eb6c17be5591264
Autor:
Sung, Yun-Min, Wilkins, Angela D., Rodriguez, Gustavo J., Wensel, Theodore G., Lichtarge, Olivier
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2016 Mar . 113(13), 3539-3544.
Externí odkaz:
https://www.jstor.org/stable/26468835
Akademický článek
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Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-19 (2022)
Scientific Reports
Scientific Reports, 2022, 12 (1), pp.820. ⟨10.1038/s41598-021-04260-1⟩
Scientific Reports
Scientific Reports, 2022, 12 (1), pp.820. ⟨10.1038/s41598-021-04260-1⟩
Despite the structural and functional information contained in the statistical coupling between pairs of residues in a protein, coevolution associated with function is often obscured by artifactual signals such as genetic drift, which shapes a protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::592cbd8a5350b12ec8f255511e2b66bb
https://doaj.org/article/e2a7e865263d40a9aab2c63c72273acb
https://doaj.org/article/e2a7e865263d40a9aab2c63c72273acb