Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Evolution and Comparative Genomics"'
Publikováno v:
Bioinformatics
Motivation: High-throughput sequencing of tumor samples has shown that most tumors exhibit extensive intra-tumor heterogeneity, with multiple subpopulations of tumor cells containing different somatic mutations. Recent studies have quantified this in
Publikováno v:
Bioinformatics
Motivation: Gene family evolution is driven by evolutionary events such as speciation, gene duplication, horizontal gene transfer and gene loss, and inferring these events in the evolutionary history of a given gene family is a fundamental problem in
Publikováno v:
Bioinformatics
Motivation: The identification of non-coding functional regions of the human genome remains one of the main challenges of genomics. By observing how a given region evolved over time, one can detect signs of negative or positive selection hinting that
Publikováno v:
Bioinformatics
Motivation: The current molecular data explosion poses new challenges for large-scale phylogenomic analyses that can comprise hundreds or even thousands of genes. A property that characterizes phylogenomic datasets is that they tend to be gappy, i.e.
Publikováno v:
Bioinformatics
Motivation: Phylogenetic tree-building methods use molecular data to represent the evolutionary history of genes and taxa. A recurrent problem is to reconcile the various phylogenies built from different genomic sequences into a single one. This task
Autor:
Alison P. Lee, Michaelle Rakotomanga, Jeremy A. Johnson, Hidenori Nishihara, Frederick J. Tan, Jessica Alföldi, Alvin Yu Jin Ng, Naoual Azzouzi, Byrappa Venkatesh, Steve Searle, Orly Eshel, Bronwen Aken, Ted Sharpe, Thomas D. Kocher, Gideon Hulata, Filipe J. Ribeiro, Eric S. Lander, Norihiro Okada, Wilfried Haerty, Thibaut Hourlier, Natalie S. Haddad, Marcia Lara, Rosa Alcazar, Karen L. Carleton, Catherine E. Wagner, Federica Di Palma, M. Emília Santos, Masato Nikaido, Eric A. Miska, Salome Mwaiko, Axel Meyer, Frédérique Barloy-Hubler, Leslie Gaffney, Sante Gnerre, David B. Jaffe, Jason Turner-Maier, David Brawand, Oleg Simakov, Lucie Greuter, Helena D'Cotta, Milan Malinsky, Iain MacCallum, Hyun Ji Noh, Shuangye Yin, Luis Sanchez-Pulido, Jean-François Baroiller, Shaohua Fan, David J. Penman, Ryan F. Bloomquist, Ross Swofford, Matthew A. Conte, Chris P. Ponting, Chris T. Amemiya, J. Todd Streelman, Richard Guyon, Hugo F. Gante, Dariusz Przybylski, Robert M Harris, Walter Salzburger, Irene Keller, Francis Galibert, Russell D. Fernald, Aaron M. Berlin, Yang I. Li, Pamela Russell, Hans A. Hofmann, Ole Seehausen, Suzy C. P. Renn, Louise Williams, Micha Ron, Kerstin Lindblad-Toh, Zhi Wei Lim, Catherine Ozouf-Costaz, Etienne Bezault, Sarah Young
Publikováno v:
Nature, vol 513, iss 7518
Nature
Nature, Nature Publishing Group, 2014, 513 (7518), pp.375-381. ⟨10.1038/nature13726⟩
PMC
Nature, 2014, 513 (7518), pp.375-381. ⟨10.1038/nature13726⟩
Brawand, David; Wagner, Catherine; Li, Yang I.; Malinsky, Milan; Keller, Irene; Fan, Shaohua; Simakov, Oleg; Ng, Alvin Y.; Lim, Zhi Wei; Bezault, Etienne; Turner-Maier, Jason; Johnson, Jeremy; Alcazar, Rosa; Noh, Hyun Ji; Russell, Pamela; Aken, Bronwen; Alföldi, Jessica; Amemiya, Chris; Azzouzi, Naoual; Baroiller, Jean-François; ... (2014). The genomic substrate for adaptive radiation in African cichlid fish. Nature, 513(7518), pp. 375-381. Macmillan Journals Ltd. 10.1038/nature13726
Nature
Nature, Nature Publishing Group, 2014, 513 (7518), pp.375-381. ⟨10.1038/nature13726⟩
PMC
Nature, 2014, 513 (7518), pp.375-381. ⟨10.1038/nature13726⟩
Brawand, David; Wagner, Catherine; Li, Yang I.; Malinsky, Milan; Keller, Irene; Fan, Shaohua; Simakov, Oleg; Ng, Alvin Y.; Lim, Zhi Wei; Bezault, Etienne; Turner-Maier, Jason; Johnson, Jeremy; Alcazar, Rosa; Noh, Hyun Ji; Russell, Pamela; Aken, Bronwen; Alföldi, Jessica; Amemiya, Chris; Azzouzi, Naoual; Baroiller, Jean-François; ... (2014). The genomic substrate for adaptive radiation in African cichlid fish. Nature, 513(7518), pp. 375-381. Macmillan Journals Ltd. 10.1038/nature13726
CC-BY-NC-SA; International audience; Cichlid fishes are famous for large, diverse and replicated adaptive radiations in the Great Lakes of East Africa. To understand the molecular mechanisms underlying cichlid phenotypic diversity, we sequenced the g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75fe19ee6d271582d43fba577bf3efe5
https://escholarship.org/uc/item/9dc9w4w1
https://escholarship.org/uc/item/9dc9w4w1
Publikováno v:
Oxford University Press
Bioinformatics
Bioinformatics
Motivation: Phylogenetic tree reconciliation is a widely used method for reconstructing the evolutionary histories of gene families and species, hosts and parasites and other dependent pairs of entities. Reconciliation is typically performed using ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dabac40e2474c78531d778e0f44fdcf9
http://hdl.handle.net/1721.1/96527
http://hdl.handle.net/1721.1/96527
Publikováno v:
Bioinformatics
Motivation: While phylogenetic analyses of datasets containing 1000–5000 sequences are challenging for existing methods, the estimation of substantially larger phylogenies poses a problem of much greater complexity and scale. Methods: We present DA
Publikováno v:
Bioinformatics
Bioinformatics, 2011, 27 (13), pp.i257-65. ⟨10.1093/bioinformatics/btr224⟩
Bioinformatics, Oxford University Press (OUP), 2011, 27 (13), pp.i257-65. ⟨10.1093/bioinformatics/btr224⟩
Bioinformatics, 2011, 27 (13), pp.i257-65. ⟨10.1093/bioinformatics/btr224⟩
Bioinformatics, Oxford University Press (OUP), 2011, 27 (13), pp.i257-65. ⟨10.1093/bioinformatics/btr224⟩
Motivation: Ancestral genomes provide a better way to understand the structural evolution of genomes than the simple comparison of extant genomes. Most ancestral genome reconstruction methods rely on universal markers, that is, homologous families of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dceb84cea280f749f726d8d711a97083
https://hal.science/hal-00680540/file/GavranovicH2011.pdf
https://hal.science/hal-00680540/file/GavranovicH2011.pdf
Publikováno v:
Bioinformatics
Bioinformatics, 2011, 27 (13), pp.i248-i256. ⟨10.1093/bioinformatics/btr210⟩
Bioinformatics, Oxford University Press (OUP), 2011, 27 (13), pp.i248-i256. ⟨10.1093/bioinformatics/btr210⟩
Bioinformatics, 2011, 27 (13), pp.i248-i256. ⟨10.1093/bioinformatics/btr210⟩
Bioinformatics, Oxford University Press (OUP), 2011, 27 (13), pp.i248-i256. ⟨10.1093/bioinformatics/btr210⟩
Motivation: In systematic biology, one is often faced with the task of comparing different phylogenetic trees, in particular in multi-gene analysis or cospeciation studies. One approach is to use a tanglegram in which two rooted phylogenetic trees ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46697677dcee84828bbeec3a88ac4baa
https://hal.science/hal-02155176
https://hal.science/hal-02155176