Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Evo Lindersson"'
Autor:
Gábor G. Kovács, Lajos László, János Kovács, Poul Henning Jensen, Evo Lindersson, Gergő Botond, Tamás Molnár, András Perczel, Ferenc Hudecz, Gábor Mező, Anna Erdei, László Tirián, Attila Lehotzky, Ellen Gelpi, Herbert Budka, Judit Ovádi
Publikováno v:
Neurobiology of Disease, Vol 17, Iss 2, Pp 155-162 (2004)
The novel basic, heat-stable tubulin polymerization promoting protein TPPP/p25 is associated with microtubules in vitro and can induce the formation of aberrant microtubule assemblies. We show by 1H-NMR spectroscopy that TPPP/p25 is natively unfolded
Externí odkaz:
https://doaj.org/article/9ee37665a9654341b7e5389ab5bdbc4c
Publikováno v:
Molecular Brain Research. 134:3-17
Biochemical and genetic evidence point towards alpha-synuclein aggregation as having a pivotal role in the onset and progression of several neurodegenerative disorders, including Parkinson's disease, multiple system atrophy and Lewy body dementia. We
Autor:
Lajos László, Ellen Gelpi, László Tirián, Poul Henning Jensen, Ferenc Hudecz, Tamás Molnár, Herbert Budka, János Kovács, Attila Lehotzky, Gergö Botond, Gábor Mezö, Judit Ovádi, Gabor G. Kovacs, Evo Lindersson, András Perczel, Anna Erdei
Publikováno v:
Neurobiology of Disease, Vol 17, Iss 2, Pp 155-162 (2004)
The novel basic, heat-stable tubulin polymerization promoting protein TPPP/p25 is associated with microtubules in vitro and can induce the formation of aberrant microtubule assemblies. We show by 1H-NMR spectroscopy that TPPP/p25 is natively unfolded
Autor:
Wei Ping Gai, Peter Højrup, Rasmus Beedholm, Poul Henning Jensen, Torben Moos, Klavs B. Hendil, Evo Lindersson
Publikováno v:
Lindersson, E, Beedholm, R, Højrup, P, Moos, T, Gai, W P, Hendil, K B & Jensen, P H 2004, ' Proteasomal inhibition by a-synuclein filaments and oligomers. ', Journal of Biological Chemistry, vol. 279, pp. 12924-12934 . https://doi.org/10.1074/jbc.M306390200
Lindersson, E, Beedholm, R, Højrup, P, Moos, T, Gai, W, Hendil, K B & Jensen, P H 2004, ' Proteasomal inhibition by alpha-synuclein filaments and oligomers ', Journal of Biological Chemistry, vol. 279, no. 13, pp. 12924-34 . https://doi.org/10.1074/jbc.M306390200
Lindersson, E, Beedholm, R, Højrup, P, Moos, T, Gai, W, Hendil, K B & Jensen, P H 2004, ' Proteasomal inhibition by alpha-synuclein filaments and oligomers ', Journal of Biological Chemistry, vol. 279, no. 13, pp. 12924-34 . https://doi.org/10.1074/jbc.M306390200
Udgivelsesdato: 2004-Mar-26 A unifying feature of many neurodegenerative disorders is the accumulation of polyubiquitinated protein inclusions in dystrophic neurons, e.g. containing alpha-synuclein, which is suggestive of an insufficient proteasomal
Publikováno v:
Journal of Extracellular Vesicles. May2024 Supplement 1, Vol. 13, p1-451. 451p.
Autor:
Jens R. Nyengaard, Ditte M.S. Lundvig, Torben Moos, Wei Ping Gai, Peter C. Blumbergs, Peter Højrup, Poul Henning Jensen, Christine Petersen, Evo Lindersson, Daniel E. Otzen, Peder Madsen
Publikováno v:
Lindersson, E, Lundvig, D, Petersen, C, Madsen, P, Højrup, P, Moos, T, Otzen, D E, Gai, W-P & Jensen, P H 2005, ' P25 alpha stimulates a-synuclein aggregation and is co-localized with aggregated alpha-synuclein in alpha-synucleinopathies ', Journal of Biological Chemistry, vol. 280, no. 7, pp. 5703-5715 . https://doi.org/10.1074/jbc.M410409200
Lindersson, E, Lundvig, D, Petersen, C, Madsen, P, Nyengaard, J R, Højrup, P, Moos, T, Otzen, D, Gai, W & Jensen, P H 2005, ' P25a stimulates a-synuclein aggregation and is co-localized with aggregated a-synuclein in a-synucleinopathies ', Journal of Biological Chemistry, vol. 280, pp. 5703-5715 . https://doi.org/10.1074/jbc.M410409200
Lindersson, E K, Lundvig, D M S, Petersen, C, Madsen, P, Nyengaard, J R, Højrup, P, Moos, T, Otzen, D, Gai, W-P, Blumbergs, P C & Jensen, P H 2005, ' p25α Stimulates α-Synuclein Aggregation and Is Co-localized with Aggregated α-Synuclein in α-Synucleinopathies ', Journal of Biological Chemistry, vol. 280, pp. 5703-5715 . https://doi.org/10.1074/jbc.M410409200
Lindersson, E, Lundvig, D, Petersen, C, Madsen, P, Nyengaard, J R, Højrup, P, Moos, T, Otzen, D, Gai, W & Jensen, P H 2005, ' P25a stimulates a-synuclein aggregation and is co-localized with aggregated a-synuclein in a-synucleinopathies ', Journal of Biological Chemistry, vol. 280, pp. 5703-5715 . https://doi.org/10.1074/jbc.M410409200
Lindersson, E K, Lundvig, D M S, Petersen, C, Madsen, P, Nyengaard, J R, Højrup, P, Moos, T, Otzen, D, Gai, W-P, Blumbergs, P C & Jensen, P H 2005, ' p25α Stimulates α-Synuclein Aggregation and Is Co-localized with Aggregated α-Synuclein in α-Synucleinopathies ', Journal of Biological Chemistry, vol. 280, pp. 5703-5715 . https://doi.org/10.1074/jbc.M410409200
Aggregation of the nerve cell protein alpha-synuclein is a characteristic of the common neurodegenerative alpha-synucleinopathies like Parkinson's disease and Lewy body dementia, and it plays a direct pathogenic role as demonstrated by early onset di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2264ee5bb50a408612853bb707394f5d
https://vbn.aau.dk/da/publications/df09a8d0-c3da-11da-b67b-000ea68e967b
https://vbn.aau.dk/da/publications/df09a8d0-c3da-11da-b67b-000ea68e967b
Autor:
Evo, Lindersson, Ditte, Lundvig, Christine, Petersen, Peder, Madsen, Jens R, Nyengaard, Peter, Højrup, Torben, Moos, Daniel, Otzen, Wei-Ping, Gai, Peter C, Blumbergs, Poul Henning, Jensen
Publikováno v:
The Journal of biological chemistry. 280(7)
Aggregation of the nerve cell protein alpha-synuclein is a characteristic of the common neurodegenerative alpha-synucleinopathies like Parkinson's disease and Lewy body dementia, and it plays a direct pathogenic role as demonstrated by early onset di
Publikováno v:
Aarhus University
alpha-Synuclein is a protein normally involved in presynaptic vesicle homeostasis. It participates in the development of Parkinson's disease, in which the nerve cell lesions, Lewy bodies, accumulate alpha-synuclein filaments. The synaptic neurotransm