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The ESCRT machinery counteracts Nesprin-2G-mediated mechanical forces during nuclear envelope repair
Autor:
Elvira Infante, Miguel Angel Cuesta-Geijo, Samuel S. Wallis, Evita Otigbah, Leandro N. Ventimiglia, Marco Foiani, Roland A. Fleck, Juan Martin-Serrano, M. Alejandra Carbajal, Monica Agromayor, Sergi Garcia-Manyes, Gururaj Rao Kidiyoor
Publikováno v:
Developmental Cell
Summary Transient nuclear envelope ruptures during interphase (NERDI) occur due to cytoskeletal compressive forces at sites of weakened lamina, and delayed NERDI repair results in genomic instability. Nuclear envelope (NE) sealing is completed by end
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f62504c483cb80e98b0b426467c48a8