Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Evisabel A, Craig"'
Publikováno v:
Journal of Cell Science. 125:5950-5954
Summary We have previously shown that the mRNA binding protein CRD-BP is overexpressed in human melanomas, where it promotes cell survival and resistance to chemotherapy. The present study investigates the role of hypoxia, a common characteristic of
Publikováno v:
Pigment Cell & Melanoma Research. 25:83-87
We previously reported that malignant melanomas express high levels of the mRNA binding protein coding region determinant binding protein (CRD-BP). This molecule is important for the activation of anti-apoptotic pathways, a mechanism often linked to
Autor:
Anita F. Austin, Richard R. Vaillancourt, Todd D. Camenisch, Joey V. Barnett, Evisabel A. Craig
Publikováno v:
Experimental Cell Research. 316:3397-3405
In the developing heart, the epicardium is a major source of progenitor cells that contribute to the formation of the coronary vessel system. These epicardial progenitors give rise to the different cellular components of the coronary vasculature by u
Publikováno v:
Cellular Signalling. 22:968-976
During embryonic development, cells comprising the outermost layer of the heart or epicardium play a critical role in the formation of the coronary vasculature. Thus, uncovering the molecular mechanisms that govern epicardial cell behavior is imperat
Publikováno v:
Glycobiology. 19:890-898
Hyaluronan (HA) induces changes in cellular behavior that are crucial during both embryonic development and cancer progression. However, the biological effects of varying sizes of HA and the signal transduction mechanisms that these polymers may acti
Publikováno v:
Journal of applied toxicology : JAT. 35(7)
The kidney is a major site of chemical excretion, which results in its propensity to exhibit chemically-induced toxicological effects at a higher rate than most other organs. Although the kidneys are often weighed in animal toxicity studies, the mann
Publikováno v:
Journal of applied toxicology : JAT. 34(7)
Developmental toxicity is a relevant endpoint for the comprehensive assessment of human health risk from chemical exposure. However, animal developmental toxicity data remain unavailable for many environmental contaminants due to the complexity and c
Autor:
Todd D. Camenisch, Anita F. Austin, Joseph D. Love, Christopher B. Brown, Evisabel A. Craig, Nora S. Sanchez, Joey V. Barnett, Cynthia R. Hill, Jonathan H. Soslow, Andras Czirok
Publikováno v:
Developmental biology. 358(2)
The epicardium is a major contributor of the cells that are required for the formation of coronary vessels. Mice lacking both copies of the gene encoding the Type III Transforming Growth Factor β Receptor (TGFβR3) fail to form the coronary vasculat
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 237(11)
The cytoplasmic serine/threonine kinases transduce extracellular signals into regulatory events that impact cellular responses. The induction of one kinase triggers the activation of several downstream kinases, leading to the regulation of transcript