The causes and consequences of Alzheimer’s disease: phenome-wide evidence from Mendelian randomization

Autor: Roxanna Korologou-Linden, Laxmi Bhatta, Ben M. Brumpton, Laura D. Howe, Louise A. C. Millard, Katarina Kolaric, Yoav Ben-Shlomo, Dylan M. Williams, George Davey Smith, Emma L. Anderson, Evie Stergiakouli, Neil M. Davies

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)

Observational studies have found overlap between Alzheimer’s disease and other diseases and phenotypes, although the causal relationships are unclear. Here, the authors perform an age-stratified phenome-wide association study of Alzheimer’s disea

Externí odkaz: https://doaj.org/article/3c47b5e997ca46068eee8dfbe504ceb6

Mitochondrial DNA haplogroups and trajectories of cardiometabolic risk factors during childhood and adolescence: A prospective cohort study.

Autor: Kate N O'Neill, Emily Aubrey, Laura D Howe, Evie Stergiakouli, Santiago Rodriguez, Patricia M Kearney, Linda M O'Keeffe

Publikováno v: PLoS ONE, Vol 18, Iss 4, p e0284226 (2023)

BackgroundMitochondria are organelles responsible for converting glucose into energy. Mitochondrial DNA is exclusively maternally inherited. The role of mitochondrial DNA haplogroups in the aetiology of cardiometabolic disease risk is not well unders

Externí odkaz: https://doaj.org/article/f1b0f3677b87457c8ccf65dda1f9900f

Preschool development, temperament and genetic liability as early markers of childhood ADHD: A cohort study

Autor: Esther Tobarra‐Sanchez, Lucy Riglin, Sharifah S. Agha, Evie Stergiakouli, Anita Thapar, Kate Langley

Publikováno v: JCPP Advances, Vol 2, Iss 3, Pp n/a-n/a (2022)

Abstract Background ADHD is associated with multiple adverse outcomes and early identification is important. The present study sets out to identify early markers and developmental characteristics during the first 30 months of life that are associated

Externí odkaz: https://doaj.org/article/0def7a9bab324ec397fad50f925b6880

Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity

Autor: Mark K. Bakker, Jos P. Kanning, Gad Abraham, Amy E. Martinsen, Bendik S. Winsvold, John-Anker Zwart, Romain Bourcier, Tomonobu Sawada, Masaru Koido, Yoichiro Kamatani, Sandrine Morel, Philippe Amouyel, Stéphanie Debette, Philippe Bijlenga, Takiy Berrandou, Santhi K. Ganesh, Nabila Bouatia-Naji, Gregory Jones, Matthew Bown, Gabriel J.E. Rinkel, Jan H. Veldink, Ynte M. Ruigrok, Anne Hege Aamodt, Anne Heidi Skogholt, Ben M Brumpton, Cristen J Willer, Else C Sandset, Espen S Kristoffersen, Hanne Ellekjær, Ingrid Heuch, Jonas B Nielsen, Knut Hagen, Kristian Hveem, Lars G Fritsche, Laurent F Thomas, Linda M Pedersen, Maiken E Gabrielsen, Oddgeir L Holmen, Sigrid Børte, Wei Zhou, Shérine Abboud, Massimo Pandolfo, Vincent Thijs, Didier Leys, Marie Bodenant, Fabien Louillet, Emmanuel Touzé, Jean-Louis Mas, Yves Samson, Sara Leder, Anne Léger, Sandrine Deltour, Sophie Crozier, Isabelle Méresse, Sandrine Canaple, Olivier Godefroy, Maurice Giroud, Yannick Béjot, Pierre Decavel, Elizabeth Medeiros, Paola Montiel, Thierry Moulin, Fabrice Vuillier, Jean Dallongeville, Antti J Metso, Tiina Metso, Turgut Tatlisumak, Caspar Grond-Ginsbach, Christoph Lichy, Manja Kloss, Inge Werner, Marie-Luise Arnold, Michael Dos Santos, Armin Grau, Martin Dichgans, Constanze Thomas-Feles, Ralf Weber, Tobias Brandt, Alessandro Pezzini, Valeria De Giuli, Filomena Caria, Loris Poli, Alessandro Padovani, Anna Bersano, Silvia Lanfranconi, Simone Beretta, Carlo Ferrarese, Giacomo Giacolone, Stefano Paolucci, Philippe Lyrer, Stefan Engelter, Felix Fluri, Florian Hatz, Dominique Gisler, Leo Bonati, Henrik Gensicke, Margareth Amort, Hugh Markus, Jennifer Majersik, Bradford Worrall, Andrew Southerland, John Cole, Steven Kittner, Evangelos Evangelou, Helen R Warren, He Gao, Georgios Ntritsos, Niki Dimou, Tonu Esko, Reedik Mägi, Lili Milani, Peter Almgren, Thibaud Boutin, Jun Ding, Franco Giulianini, Elizabeth G Holliday, Anne U Jackson, Ruifang Li-Gao, Wei-Yu Lin, Jian’an Luan, Massimo Mangino, Christopher Oldmeadow, Bram Peter Prins, Yong Qian, Muralidharan Sargurupremraj, Nabi Shah, Praveen Surendran, Sébastien Thériault, Niek Verweij, Sara M Willems, Jing-Hua Zhao, John Connell, Renée de Mutsert, Alex SF Doney, Martin Farrall, Cristina Menni, Andrew D Morris, Raymond Noordam, Guillaume Paré, Neil R Poulter, Denis C Shields, Alice Stanton, Simon Thom, Gonçalo Abecasis, Najaf Amin, Dan E Arking, Kristin L Ayers, Caterina M Barbieri, Chiara Batini, Joshua C Bis, Tineka Blake, Murielle Bochud, Michael Boehnke, Eric Boerwinkle, Dorret I Boomsma, Erwin P Bottinger, Peter S Braund, Marco Brumat, Archie Campbell, Harry Campbell, Aravinda Chakravarti, John C Chambers, Ganesh Chauhan, Marina Ciullo, Massimiliano Cocca, Francis Collins, Heather J Cordell, Gail Davies, Martin H de Borst, Eco J de Geus, Ian J Deary, Joris Deelen, Fabiola Del Greco M, Cumhur Yusuf Demirkale, Marcus Dörr, Georg B Ehret, Roberto Elosua, Stefan Enroth, A Mesut Erzurumluoglu, Teresa Ferreira, Mattias Frånberg, Oscar H Franco, Ilaria Gandin, Paolo Gasparini, Vilmantas Giedraitis, Christian Gieger, Giorgia Girotto, Anuj Goel, Alan J Gow, Vilmundur Gudnason, Xiuqing Guo, Ulf Gyllensten, Anders Hamsten, Tamara B Harris, Sarah E Harris, Catharina A Hartman, Aki S Havulinna, Andrew A Hicks, Edith Hofer, Albert Hofman, Jouke-Jan Hottenga, Jennifer E Huffman, Shih-Jen Hwang, Erik Ingelsson, Alan James, Rick Jansen, Marjo-Riitta Jarvelin, Roby Joehanes, Åsa Johansson, Andrew D Johnson, Peter K Joshi, Pekka Jousilahti, J Wouter Jukema, Antti Jula, Mika Kähönen, Sekar Kathiresan, Bernard D Keavney, Kay-Tee Khaw, Paul Knekt, Joanne Knight, Ivana Kolcic, Jaspal S Kooner, Seppo Koskinen, Kati Kristiansson, Zoltan Kutalik, Maris Laan, Marty Larson, Lenore J Launer, Benjamin Lehne, Terho Lehtimäki, David CM Liewald, Li Lin, Lars Lind, Cecilia M Lindgren, YongMei Liu, Ruth JF Loos, Lorna M Lopez, Yingchang Lu, Leo-Pekka Lyytikäinen, Anubha Mahajan, Chrysovalanto Mamasoula, Jaume Marrugat, Jonathan Marten, Yuri Milaneschi, Anna Morgan, Andrew P Morris, Alanna C Morrison, Peter J Munson, Mike A Nalls, Priyanka Nandakumar, Christopher P Nelson, Teemu Niiranen, Ilja M Nolte, Teresa Nutile, Albertine J Oldehinkel, Ben A Oostra, Paul F O’Reilly, Elin Org, Sandosh Padmanabhan, Walter Palmas, Aarno Palotie, Alison Pattie, Brenda WJH Penninx, Markus Perola, Annette Peters, Ozren Polasek, Peter P Pramstaller, Quang Tri Nguyen, Olli T Raitakari, Rainer Rettig, Kenneth Rice, Paul M Ridker, Janina S Ried, Harriëtte Riese, Samuli Ripatti, Antonietta Robino, Lynda M Rose, Jerome I Rotter, Igor Rudan, Daniela Ruggiero, Yasaman Saba, Cinzia F Sala, Veikko Salomaa, Nilesh J Samani, Antti-Pekka Sarin, Reinhold Schmidt, Helena Schmidt, Nick Shrine, David Siscovick, Albert V Smith, Harold Snieder, Siim Sõber, Rossella Sorice, John M Starr, David J Stott, David P Strachan, Rona J Strawbridge, Johan Sundström, Morris A Swertz, Kent D Taylor, Alexander Teumer, Martin D Tobin, Maciej Tomaszewski, Daniela Toniolo, Michela Traglia, Stella Trompet, Jaakko Tuomilehto, Christophe Tzourio, André G Uitterlinden, Ahmad Vaez, Peter J van der Most, Cornelia M van Duijn, Germaine C Verwoert, Veronique Vitart, Uwe Völker, Peter Vollenweider, Dragana Vuckovic, Hugh Watkins, Sarah H Wild, Gonneke Willemsen, James F Wilson, Alan F Wright, Jie Yao, Tatijana Zemunik, Weihua Zhang, John R Attia, Adam S Butterworth, Daniel I Chasman, David Conen, Francesco Cucca, John Danesh, Caroline Hayward, Joanna MM Howson, Markku Laakso, Edward G Lakatta, Claudia Langenberg, Olle Melander, Dennis O Mook-Kanamori, Colin NA Palmer, Lorenz Risch, Robert A Scott, Rodney J Scott, Peter Sever, Tim D Spector, Pim van der Harst, Nicholas J Wareham, Eleftheria Zeggini, Daniel Levy, Patricia B Munroe, Christopher Newton-Cheh, Morris J Brown, Andres Metspalu, Bruce M. Psaty, Louise V Wain, Paul Elliott, Mark J Caulfield, Padhraig Gormley, Verneri Anttila, Priit Palta, Tune H Pers, Kai-How Farh, Ester Cuenca-Leon, Mikko Muona, Nicholas A Furlotte, Tobias Kurth, Andres Ingason, George McMahon, Lannie Ligthart, Gisela M Terwindt, Mikko Kallela, Tobias M Freilinger, Caroline Ran, Scott G Gordon, Anine H Stam, Stacy Steinberg, Guntram Borck, Markku Koiranen, Lydia Quaye, Hieab H H Adams, Juho Wedenoja, David A Hinds, Julie E Buring, Markus Schürks, Maria Gudlaug Hrafnsdottir, Hreinn Stefansson, Susan M Ring, Brenda W J H Penninx, Markus Färkkilä, Ville Artto, Mari Kaunisto, Salli Vepsäläinen, Rainer Malik, Andrew C Heath, Pamela A F Madden, Nicholas G Martin, Grant W Montgomery, Mitja I Kurki, Mart Kals, Kalle Pärn, Eija Hämäläinen, Hailiang Huang, Andrea E Byrnes, Lude Franke, Jie Huang, Evie Stergiakouli, Phil H Lee, Cynthia Sandor, Caleb Webber, Zameel Cader, Bertram Muller-Myhsok, Stefan Schreiber, Thomas Meitinger, Johan G Eriksson, Kauko Heikkilä, Elizabeth Loehrer, Andre G Uitterlinden, Lynn Cherkas, Audun Stubhaug, Christopher S Nielsen, Minna Männikkö, Evelin Mihailov, Hartmut Göbel, Ann-Louise Esserlind, Anne Francke Christensen, Thomas Folkmann Hansen, Thomas Werge, Jaakko Kaprio, Arpo J Aromaa, Olli Raitakari, M Arfan Ikram, Tim Spector, Marjo-Riitta Järvelin, Christian Kubisch, Michel D Ferrari, Andrea C Belin, Maija Wessman, Arn M J M van den Maagdenberg, George Davey Smith, Kari Stefansson, Nicholas Eriksson, Mark J Daly, Benjamin M Neale, Jes Olesen, Dale R Nyholt, Masato Akiyama, Varinder S. Alg, Joseph P. Broderick, Ben M. Brumpton, Jérôme Dauvillier, Hubert Desal, Christian Dina, Christoph M. Friedrich, Emília I. Gaál-Paavola, Jean-Christophe Gentric, Sven Hirsch, Isabel C. Hostettler, Henry Houlden, Juha E. Jääskeläinen, Marianne Bakke Johnsen, Liming Li, Kuang Lin, Antti Lindgren, Olivier Martin, Koichi Matsuda, Iona Y. Millwood, Olivier Naggara, Mika Niemelä, Joanna Pera, Richard Redon, Guy A. Rouleau, Marie Søfteland Sandvei, Sabine Schilling, Eimad Shotar, Agnieszka Slowik, Chikashi Terao, W. M. Monique Verschuren, Robin G. Walters, David J. Werring, Cristen J. Willer, Daniel Woo, Bradford B. Worrall, Sirui Zhou

Publikováno v: Bakker, M K, Kanning, J P, Abraham, G, Martinsen, A E, Winsvold, B S, Zwart, J-A, Bourcier, R, Sawada, T, Koido, M, Kamatani, Y, Morel, S, Amouyel, P, Debette, S, Bijlenga, P, Berrandou, T, Ganesh, S K, Bouatia-Naji, N, Jones, G, Bown, M, Rinkel, G J E, Veldink, J H, Ruigrok, Y M, Hege Aamodt, A, Heidi Skogholt, A, Brumpton, B M, Willer, C J, Sandset, E C, Kristoffersen, E S, Ellekjær, H, Heuch, I, Nielsen, J B, Hagen, K, Hveem, K, Fritsche, L G, Thomas, L F, Pedersen, L M, Gabrielsen, M E, Holmen, O L, Børte, S, Zhou, W, Abboud, S, Pandolfo, M, Thijs, V, Leys, D, Bodenant, M, Louillet, F, Touzé, E, Mas, J-L, Samson, Y, Leder, S, Léger, A, Deltour, S, Crozier, S, Méresse, I, Canaple, S, Godefroy, O, Giroud, M, Béjot, Y, Decavel, P, Medeiros, E, Montiel, P, Moulin, T, Vuillier, F, Dallongeville, J, Metso, A J, Metso, T, Tatlisumak, T, Grond-Ginsbach, C, Lichy, C, Kloss, M, Werner, I, Arnold, M-L, Dos Santos, M, Grau, A, Dichgans, M, Thomas-Feles, C, Weber, R, Brandt, T, Pezzini, A, de Giuli, V, Caria, F, Poli, L, Padovani, A, Bersano, A, Lanfranconi, S, Beretta, S, Ferrarese, C, Giacolone, G, Paolucci, S, Lyrer, P, Engelter, S, Fluri, F, Hatz, F, Gisler, D, Bonati, L, Gensicke, H, Amort, M, Markus, H, Majersik, J, Worrall, B, Southerland, A, Cole, J, Kittner, S, Evangelou, E, Warren, H R, Gao, H, Ntritsos, G, Dimou, N, Esko, T, Mägi, R, Milani, L, Almgren, P, Boutin, T, Ding, J, Giulianini, F, Holliday, E G, Jackson, A U, Li-Gao, R, Lin, W-Y, Luan, J, Mangino, M, Oldmeadow, C, Peter Prins, B, Qian, Y, Sargurupremraj, M, Shah, N, Surendran, P, Thériault, S B, Verweij, N, Willems, S M, Zhao, J-H, Connell, J, de Mutsert, R, Doney, A S F, Farrall, M, Menni, C, Morris, A D, Noordam, R, Paré, G, Poulter, N R, Shields, D C, Stanton, A, Thom, S, Abecasis, G, Amin, N, Arking, D E, Ayers, K L, Barbieri, C M, Batini, C, Bis, J C, Blake, T, Bochud, M, Boehnke, M, Boerwinkle, E, Boomsma, D I, Bottinger, E P, Braund, P S, Brumat, M, Campbell, A, Campbell, H, Chakravarti, A, Chambers, J C, Chauhan, G, Ciullo, M, Cocca, M, Collins, F, Cordell, H J, Davies, G, de Borst, M H, de Geus, E J, Deary, I J, Deelen, J, del Greco M, F, Yusuf Demirkale, C, Dörr, M, Ehret, G B, Elosua, R, Enroth, S, Mesut Erzurumluoglu, A, Ferreira, T, Frånberg, M, Franco, O H, Gandin, I, Gasparini, P, Giedraitis, V, Gieger, C, Girotto, G, Goel, A, Gow, A J, Gudnason, V, Guo, X, Gyllensten, U, Hamsten, A, Harris, T B, Harris, S E, Hartman, C A, Havulinna, A S, Hicks, A A, Hofer, E, Hofman, A, Hottenga, J-J, Huffman, J E, Hwang, S-J, Ingelsson, E, James, A, Jansen, R, Jarvelin, M-R, Joehanes, R, Johansson, Å, Johnson, A D, Joshi, P K, Jousilahti, P, Wouter Jukema, J, Jula, A, Kähönen, M, Kathiresan, S, Keavney, B D, Khaw, K-T, Knekt, P, Knight, J, Kolcic, I, Kooner, J S, Koskinen, S, Kristiansson, K, Kutalik, Z, Laan, M, Larson, M, Launer, L J, Lehne, B, Lehtimäki, T, Liewald, D C M, Lin, L, Lind, L, Lindgren, C M, Liu, Y, Loos, R J F, Lopez, L M, Lu, Y, Lyytikäinen, L-P, Mahajan, A, Mamasoula, C, Marrugat, J, Marten, J, Milaneschi, Y, Morgan, A, Morris, A P, Morrison, A C, Munson, P J, Nalls, M A, Nandakumar, P, Nelson, C P, Niiranen, T, Nolte, I M, Nutile, T, Oldehinkel, A J, Oostra, B A, O'reilly, P F, Org, E, Padmanabhan, S, Palmas, W, Palotie, A, Pattie, A, Wjh Penninx, B, Perola, M, Peters, A, Polasek, O, Pramstaller, P P, Tri Nguyen, Q, Raitakari, O T, Rettig, R, Rice, K, Ridker, P M, Ried, J S, Riese, H, Ripatti, S, Robino, A, Rose, L M, Rotter, J I, Rudan, I, Ruggiero, D, Saba, Y, Sala, C F, Salomaa, V, Samani, N J, Sarin, A-P, Schmidt, R, Schmidt, H, Shrine, N, Siscovick, D, Smith, A V, Snieder, H, Sõber, S, Sorice, R, Starr, J M, Stott, D J, Strachan, D P, Strawbridge, R J, Sundström, J, Swertz, M A, Taylor, K D, Teumer, A, Tobin, M D, Tomaszewski, M, Toniolo, D, Traglia, M, Trompet, S, Tuomilehto, J, Tzourio, C, Uitterlinden, A G, Vaez, A, van der Most, P J, van Duijn, C M, Verwoert, G C, Vitart, V, Völker, U, Vollenweider, P, Vuckovic, D, Watkins, H, Wild, S H, Willemsen, G, Wilson, J F, Wright, A F, Yao, J, Zemunik, T, Zhang, W, Attia, J R, Butterworth, A S, Chasman, D I, Conen, D, Cucca, F, Danesh, J, Hayward, C, Howson, J M M, Laakso, M, Lakatta, E G, Langenberg, C, Melander, O, Mook-Kanamori, D O, Palmer, C N A, Risch, L, Scott, R A, Scott, R J, Sever, P, Spector, T D, van der Harst, P, Wareham, N J, Zeggini, E, Levy, D, Munroe, P B, Newton-Cheh, C, Brown, M J, Metspalu, A, Psaty, B M, Wain, L V, Elliott, P, Caulfield, M J, Gormley, P, Anttila, V, Palta, P, Esko, T, Pers, T H, Farh, K-H, Cuenca-Leon, E, Muona, M, Furlotte, N A, Kurth, T, Ingason, A, Mcmahon, G, Ligthart, L, Terwindt, G M, Kallela, M, Freilinger, T M, Ran, C, Gordon, S G, Stam, A H, Steinberg, S, Borck, G, Koiranen, M, Quaye, L, Adams, H H H, Lehtimäki, T, Sarin, A-P, Wedenoja, J, Hinds, D A, Buring, J E, Schürks, M, Ridker, P M, Gudlaug Hrafnsdottir, M, Stefansson, H, Ring, S M, Hottenga, J-J, Penninx, B W J H, Färkkilä, M, Artto, V, Kaunisto, M, Vepsäläinen, S, Malik, R, Heath, A C, Madden, P A F, Martin, N G, Montgomery, G W, Kurki, M I, Kals, M, Mägi, R, Pärn, K, Hämäläinen, E, Huang, H, Byrnes, A E, Franke, L, Huang, J, Stergiakouli, E, Lee, P H, Sandor, C, Webber, C, Cader, Z, Muller-Myhsok, B, Schreiber, S, Meitinger, T, Eriksson, J G, Salomaa, V, Heikkilä, K, Loehrer, E, Uitterlinden, A G, Hofman, A, van Duijn, C M, Cherkas, L, Pedersen, L M, Stubhaug, A, Nielsen, C S, Männikkö, M, Mihailov, E, Milani, L, Göbel, H, Esserlind, A-L, Francke Christensen, A, Folkmann Hansen, T, Werge, T, Kaprio, J, Aromaa, A J, Raitakari, O, Arfan Ikram, M, Spector, T, Järvelin, M-R, Metspalu, A, Kubisch, C, Strachan, D P, Ferrari, M D, Belin, A C, Dichgans, M, Wessman, M, van den Maagdenberg, A M J M, Boomsma, D I, Davey Smith, G, Stefansson, K, Eriksson, N, Daly, M J, Neale, B M, Olesen, J, Chasman, D I, Nyholt, D R, Palotie, A, Akiyama, M, Alg, V S, Børte, S, Broderick, J P, Brumpton, B M, Dauvillier, J R, Desal, H, Dina, C, Friedrich, C M, Gaál-Paavola, E I, Gentric, J-C, Hirsch, S, Hostettler, I C, Houlden, H, Hveem, K, Jääskeläinen, J E, Johnsen, M B, Li, L, Lin, K, Lindgren, A, Martin, O, Matsuda, K, Millwood, I Y, Naggara, O, Niemelä, M, Pera, J, Redon, R, Rouleau, G A, Sandvei, M S F, Schilling, S, Shotar, E, Slowik, A, Terao, C, Verschuren, W M M, Walters, R G, Werring, D J, Willer, C J, Woo, D, Worrall, B B & Zhou, S 2023, ' Genetic Risk Score for Intracranial Aneurysms : Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity ', Stroke, vol. 54, no. 3, pp. 810-818 . https://doi.org/10.1161/STROKEAHA.122.040715
Stroke, 54(3), 810-818. Lippincott Williams and Wilkins
Bakker, M K, Kanning, J P, Abraham, G, Rinkel, G J E, Veldink, J H, Ruigrok, Y M, Boomsma, D I, de Geus, E J C, Hottenga, J-J, Jansen, R, Milaneschi, Y, Willemsen, G, Ligthart, L & The International Headache Genetics Consortium (IHGC) 2023, ' Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity ', Stroke, vol. 54, no. 3, pp. 810-818 . https://doi.org/10.1161/STROKEAHA.122.040715
Stroke
Stroke, 2023, 54 (3), pp.810-818. ⟨10.1161/strokeaha.122.040715⟩
Bakker, M K, Kanning, J P, Abraham, G, Martinsen, A E, Winsvold, B S, Zwart, J-A, Bourcier, R, Sawada, T, Koido, M, Kamatani, Y, Morel, S, Amouyel, P, Debette, S, Bijlenga, P, Berrandou, T, Ganesh, S K, Bouatia-Naji, N, Jones, G, Bown, M, Rinkel, G J E & Veldink, J H & Ruigrok, Y M 2023, ' Genetic Risk Score for Intracranial Aneurysms : Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity ', Stroke, vol. 54, no. 3, pp. 810-818 . https://doi.org/10.1161/STROKEAHA.122.040715
Stroke, 2023, ⟨10.1161/strokeaha.122.040715⟩

Background: Recently, common genetic risk factors for intracranial aneurysm (IA) and aneurysmal subarachnoid hemorrhage (ASAH) were found to explain a large amount of disease heritability and therefore have potential to be used for genetic risk predi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36628fefb56d299663379ef5e8719f53
https://doi.org/10.1161/strokeaha.122.040715

Early manifestations of genetic liability for ADHD, autism and schizophrenia at ages 18 and 24 months

Autor: Lucy Riglin, Esther Tobarra‐Sanchez, Evie Stergiakouli, Alexandra Havdahl, Kate Tilling, Michael O’Donovan, Joel Nigg, Kate Langley, Anita Thapar

Publikováno v: Riglin, L, Tobarra-Sanchez, E, Stergiakouli, E, Havdahl, A, Tilling, K M, O'Donovan, M C, Nigg, J, Langley, K & Thapar, A 2022, ' Early manifestations of genetic liability for ADHD, autism and schizophrenia at ages 18 and 24 months ', JCPP Advances, vol. 2, no. 3, e12093 . https://doi.org/10.1002/jcv2.12093

BackgroundADHD and autism are neurodevelopmental conditions, for which non-specific precursors or early signs include difficulties with language and motor skills, and differences in temperament in the first and second year of life. These early featur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9759e16243861fa1de8bea86719090db
https://pubmed.ncbi.nlm.nih.gov/36545360