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Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion

Publikováno v: PMC

Prior studies have identified recurrent oncogenic mutations in colorectal adenocarcinoma1 and have surveyed exons of protein-coding genes for mutations in 11 affected individuals2,3. Here we report whole-genome sequencing from nine individuals with c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2491402bd8067379b53c25f2ffbdb57c
https://doi.org/10.1038/ng.936

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Comparing metastatic (M) young onset (YO) colorectal cancer (CRC) with average onset (AO): Do they differ clinically and genetically?

Autor: Anna M. Varghese, J.F. Hechtman, Nikolaus Schultz, Neil H. Segal, L. B. Saltz, David M. Hyman, J. Garcia Aguilar, Evi Vakiani, Jinru Shia, Andrea Cercek, Walid K. Chatila, Luis A. Diaz, G. Dos Santos Fernandes, Diane Lauren Reidy, M.F. Berger, Zsofia K. Stadler, Robin B. Mendelsohn, Rona Yaeger, David B. Solit

Publikováno v: Annals of Oncology. 29:viii197

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d044e8bd673e4a521525b1a4054d3317
https://doi.org/10.1093/annonc/mdy281.137

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Clinical next generation sequencing (NGS) of esophagogastric (EG) adenocarcinomas identifies distinct molecular signatures of response to HER2 inhibition, first-line 5FU/platinum and PD1/CTLA4 blockade

Autor: Philip Jonsson, Yaelle Tuvy, Evi Vakiani, Laura H. Tang, David P. Kelsen, David B. Solit, D. Ilson, Margaret K. Callahan, Geoffrey Y. Ku, Jamie Riches, Nancy Bouvier, J.F. Hechtman, M.F. Berger, Nikolaus Schultz, Francisco Sanchez-Vega, Zsofia K. Stadler, Ritika Kundra, Yelena Y. Janjigian, Barry S. Taylor

Publikováno v: Annals of Oncology. 27:vi208

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8e326c1997b03382dd3e50f40b8c0970
https://doi.org/10.1093/annonc/mdw371.04

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P2.08 Emergence of Kras Mutations and Acquired Resistance to Anti Egfr Therapy in Colorectal Cancer

Publikováno v: Annals of Oncology. 23:v24

A main limitation of therapies that selectively target kinase signaling pathways is the emergence of secondary drug resistance. Cetuximab, a monoclonal antibody that binds the extracellular domain of EGFR, is effective in a subset of KRAS wild type m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ff07481f3cbd7a97ae1388ba4c8fd6e
https://doi.org/10.1016/s0923-7534(20)31331-4

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Sirolimus-associated hepatotoxicity: case report and review of the literature

Autor: Evi Vakiani, Robert S. Brown, Jun Lee, Rhonda K. Yantiss, Samuel H. Sigal, Brock Macdonald

Publikováno v: Transplant Research and Risk Management. :1

Brock Macdonald1 Evi Vakiani2 Rhonda K Yantiss3 Jun Lee4 Robert S Brown Jr5 Samuel H Sigal6 1Division of Gastroenterology, Department of Medicine, University of California-San Francisco, San Francisco, CA, 2Department of Pathology, Memorial Sloan–K

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a6cbcf0fa1f060cb2138b97fb37738ad
https://doi.org/10.2147/trrm.s21313

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Sirolimus-Induced Hepatotoxicity

Autor: Samuel H. Sigal, Evi Vakiani, Robert S. Brown, Brock Macdonald

Publikováno v: American Journal of Gastroenterology. 103:S157

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a7e9b761b46404a53b00139d1bac8dd4
https://doi.org/10.14309/00000434-200809001-00407

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P-517 A phase II study of irinotecan, cisplatin, and mitomycin C (IPM) in malignant pleural mesothelioma

Autor: Jeremy P.C. Steele, Jonathan Shamash, Robin M. Rudd, N.H. Gower, Evi Vakiani, Claire Barlow, Dean A. Fennell, M.T. Evans, Michael Sheaff, Paula Wells

Publikováno v: Lung Cancer. 41:S221

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f52add6e77187353ae815e048c325ad0
https://doi.org/10.1016/s0169-5002(03)92484-6

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P-518 Second line therapy of malignant pleural mesothelioma with irinotecan, cisplatin, and mitomycin C (IPM): A phase II study

Autor: Evi Vakiani, Michael Sheaff, Jeremy P.C. Steele, Robin M. Rudd, M.T. Evans, N.H. Gower, Claire Barlow, Dean A. Fennell, Paula Wells, Jonathan Shamash

Publikováno v: Lung Cancer. 41:S221

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::414548e9ad3627473f169adf133202ad
https://doi.org/10.1016/s0169-5002(03)92485-8

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