Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Evi Struble"'
Autor:
Yong He, Lilin Zhong, Hailing Yan, Maria Luisa Virata, Lu Deng, Ashish K. Mishra, Evi Struble, Dorothy Scott, Pei Zhang
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 6 (2024)
ABSTRACT Human immunoglobulin preparations contain a diverse range of polyclonal antibodies that reflect past immune responses against pathogens encountered by the blood donor population. In this study, we examined a panel of intravenous immunoglobul
Externí odkaz:
https://doaj.org/article/96f12649218c499ba37e7dbe922b0f3f
Autor:
Zhong Zhao, Lilin Zhong, Elizabeth Elrod, Evi Struble, Li Ma, Hailing Yan, Christine Harman, Lu Deng, Maria Luisa Virata-Theimer, Peter Liu, Harvey Alter, Arash Grakoui, Pei Zhang
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84346 (2014)
The identification of a specific immunogenic candidate that will effectively activate the appropriate pathway for neutralizing antibody production is fundamental for vaccine design. By using a monoclonal antibody (1H8) that neutralizes HCV in vitro,
Externí odkaz:
https://doaj.org/article/342788b0a1f24c9ab387e7a69e3a948d
Autor:
Sreya Tarafdar, Yanqun Xu, Maria Luisa Virata, Evi Struble, Hailing Yan, Lu Deng, Lilin Zhong, Pei Zhang, Yong He
Publikováno v:
Journal of Medical Virology. 94:649-658
Hepatitis B Immune Globulin (HBIG) is a human plasma-derived IgG concentrate that contains a high titer of neutralizing antibodies (anti-HBs) to the hepatitis B virus (HBV) surface antigen (HBsAg). HBIG is known to be highly effective in treating HBV
Autor:
Akos Herzeg, Graça Almeida‐Porada, R. Alta Charo, Anna L. David, Juan Gonzalez‐Velez, Nalin Gupta, Larissa Lapteva, Billie Lianoglou, William Peranteau, Christopher Porada, Stephan J. Sanders, Teresa N. Sparks, David H. Stitelman, Evi Struble, Charlotte J. Sumner, Tippi C. MacKenzie
Publikováno v:
Journal of clinical pharmacology. 62
We are living in a golden age of medicine in which the availability of prenatal diagnosis, fetal therapy, and gene therapy/editing make it theoretically possible to repair almost any defect in the genetic code. Furthermore, the ability to diagnose ge
Autor:
Harvey J. Alter, Nancy E. Hernandez, Pei Zhang, David D. Holcomb, Lu Deng, Yong He, Evi Struble, Yanqun Xu, Maria Luisa Virata, Hailing Yan, Sreya Tarafdar, Lilin Zhong
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Epitope III, a segment on the E2 glycoprotein of the hepatitis C virus (HCV) which binds to the host receptor CD81, is a key target for antibodies to block HCV entry. By solving the atomic structure of epitope III bound to a site-specifi
Autor:
Evi Struble, Sanaz Momben-Abolfath, Pei Zhang, Yanqun Xu, Nancy Eller, Dorothy E. Scott, Malgorzata G. Norton, Yong He
Publikováno v:
Vaccines, Vol 9, Iss 145, p 145 (2021)
Vaccines
Volume 9
Issue 2
Vaccines
Volume 9
Issue 2
Zika virus (ZIKV) infections have been associated with an increased incidence of severe microcephaly and other neurodevelopmental disorders in newborn babies. Passive immunization with anti-ZIKV neutralizing antibodies has the potential to become a f
Autor:
Dorothy E. Scott, Evi Struble, Mikhail V Ovanesov, Yanqun Xu, Michael Eckhaus, Daryl Despres, Yideng Liang, Leonid A. Parunov
Publikováno v:
Thrombosis Journal
Thrombosis Journal, Vol 18, Iss 1, Pp 1-10 (2020)
Thrombosis Journal, Vol 18, Iss 1, Pp 1-10 (2020)
Background Pregnant women are at increased risk of thrombotic adverse events. Plasma derived immune globulin (IG) products, which are used in pregnancy for various indications, may contain procoagulant impurity activated coagulation factor XI (FXIa).
Autor:
Christine Stuart, Li Ma, Pei Zhang, Shelby A. Dahlen, Yanqun Xu, Denise Toibero, Lilin Zhong, Zhong Zhao, Malgorzata G. Norton, Evi Struble
Publikováno v:
Placenta
Introduction When administered during pregnancy, antibodies and other biologic drugs that contain the Fc part of the IgG molecule can traverse the placenta. Although it is generally accepted that the FcRn receptor mediates this process, gaps remain i
Publikováno v:
Birth Defects Research Part C: Embryo Today: Reviews. 105:190-200
Pregnancy is a hypercoagulable state which carries an excess risk of maternal venous thrombosis. Endothelial injury, alterations in blood flow and activation of the coagulation pathway are proposed to contribute to the hypercoagulability. The risk fo
Autor:
Harvey J. Alter, Lilin Zhong, Evi Struble, Hailing Yan, Lu Deng, Zhong Zhao, Li Ma, Stephen Feinstone, Pei Zhang, Maria Luisa Virata-Theimer
Publikováno v:
Proceedings of the National Academy of Sciences. 111:10690-10695
The X-ray crystal structure of epitope II on the E2 protein of hepatitis C virus, in complex with nonneutralizing antibody mAb#12, has been solved at 2.90-Å resolution. The spatial arrangement of the essential components of epitope II (ie, the C-ter