Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Evi P. Vlachou"'
Autor:
Anastasia Gkeka, Francisco Aresta-Branco, Gianna Triller, Evi P. Vlachou, Monique van Straaten, Mirjana Lilic, Paul Dominic B. Olinares, Kathryn Perez, Brian T. Chait, Renata Blatnik, Thomas Ruppert, Joseph P. Verdi, C. Erec Stebbins, F. Nina Papavasiliou
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112262- (2023)
Summary: The African trypanosome survives the immune response of its mammalian host by antigenic variation of its major surface antigen (the variant surface glycoprotein or VSG). Here we describe the antibody repertoires elicited by different VSGs. W
Externí odkaz:
https://doaj.org/article/eb43510b214a4df1a0e7c607d76c984e
Autor:
Gianna Triller, Evi P. Vlachou, Hamidreza Hashemi, Monique van Straaten, Johan P. Zeelen, Yosip Kelemen, Carly Baehr, Cheryl L. Marker, Sandra Ruf, Anna Svirina, Monica Chandra, Katharina Urban, Anastasia Gkeka, Sebastian Kruse, Andreas Baumann, Aubry K. Miller, Marc Bartel, Marco Pravetoni, C. Erec Stebbins, F. Nina Papavasiliou, Joseph P. Verdi
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 112049- (2023)
Summary: Poorly immunogenic small molecules pose challenges for the production of clinically efficacious vaccines and antibodies. To address this, we generate an immunization platform derived from the immunogenic surface coat of the African trypanoso
Externí odkaz:
https://doaj.org/article/c7ecefeb83cd43648db62b9d9e7b1931
Autor:
Sara Đaković, Johan Zeelen, Anastasia Gkeka, Monica Chandra, Konstantina Foti, Monique van Straaten, Evi P. Vlachou, Francisco Aresta-Branco, Joseph P. Verdi, F. Nina Papavasiliou, C. Erec Stebbins
Long-term immune evasion by the African trypanosome is achieved through repetitive cycles of surface protein replacement with antigenically distinct versions of the dense Variant Surface Glycoprotein (VSG) coat. Thousands of VSG genes and pseudo-gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::179000f3d891701a475f60f9573db530
https://doi.org/10.1101/2023.02.04.525354
https://doi.org/10.1101/2023.02.04.525354
Autor:
Gianna Triller, Evi P. Vlachou, Hamidreza Hashemi, Monique van Straaten, Johan Zeelen, Yosip Kelemen, Carly Baehr, Cheryl L. Marker, Sandra Ruf, Anna Svirina, Sebastian Kruse, Andreas Baumann, Aubry K. Miller, Marc Bartel, Marco Pravetoni, C. Erec Stebbins, F. Nina Papavasiliou, Joseph P. Verdi
Publikováno v:
SSRN Electronic Journal.
SummaryPoorly antigenic small molecules pose challenges for the production of clinically efficacious antibodies. To address this, we have developed an immunization platform derived from the antigenic surface coat of the African trypanosome. Through s