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pro vyhledávání: '"Ević Valentina"'
Autor:
Ević Valentina, Rokov-Plavec Jasmina
Publikováno v:
Arhiv za Higijenu Rada i Toksikologiju, Vol 75, Iss 2, Pp 147-154 (2024)
Mistakes in translation are mostly associated with toxic effects in the cell due to the production of functionally aberrant and misfolded proteins. However, under certain circumstances mistranslation can have beneficial effects and enable cells to pr
Externí odkaz:
https://doaj.org/article/3ec1128aba6541018aed4d412e053b0b
Akademický článek
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Autor:
Ević, Valentina1 (AUTHOR), Rokov-Plavec, Jasmina1 (AUTHOR) rokov@chem.pmf.hr
Publikováno v:
Archives of Industrial Hygiene & Toxicology / Arhiv za Higijenu Rada I Toksikologiju. Jun2024, Vol. 75 Issue 2, p147-154. 8p.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Translation is an essential cellular process in protein biosynthesis. Enzymes aminoacyl-tRNA synthetases (aaRS) have a key role as they attach tRNAs with their cognate amino acids. Aminoacylation is a two-step reaction consisting of: activation of am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::c43834db90c9bc98d3db78d98c26c2dd
https://www.bib.irb.hr/1191565
https://www.bib.irb.hr/1191565
Autor:
Ević, Valentina, Šoić, Ružica, Matković-Čalogović, Dubravka, Gruić Sovulj, Ita, Kekez, Ivana, Rokov Plavec, Jasmina
In general, cytosolic proteins do not contain disulfide bonds due to high reducing power of the cytosol. Previously, we have identified a unique disulfide bond between Cys213 and Cys244 in the crystal structure of cytosolic seryl-tRNA synthetase (Ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::f66cfa89574cce5b2f57d43e6785e608
https://www.bib.irb.hr/1221086
https://www.bib.irb.hr/1221086
Mistranslation can occur due to inaccurate amino acid selection by aminoacyl-tRNA synthetases (aaRSs). Although usually toxic, due to the production of aberrant proteins, there are a few examples of its adaptive effect on cellular responses to subseq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::8a020820a167acdf16e577ebe310abd9
https://www.bib.irb.hr/1219572
https://www.bib.irb.hr/1219572
Reactive oxygen species (ROS) are byproduct of bacterial aerobic metabolism, however, if the metabolism is disrupted, amount of ROS increases beyond cell's capacity which causes oxidative stress. Additionally, oxidative stress can be caused by other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::ffdd527bc655241f5ea6159f33bbf8f4
https://www.bib.irb.hr/1219582
https://www.bib.irb.hr/1219582
Mistakes during translation can occur due to inaccurate amino acid selection by aminoacyl- tRNA synthetases (aaRSs). Some aaRSs possess editing domain and hydrolyze incorrect aa-tRNA product. Although mistranslation is usually toxic due to production
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::6719f2fd56849c9ebf167dfb4459bd00
https://doi.org/10.1002/2211-5463.13205
https://doi.org/10.1002/2211-5463.13205
Translation is a cellular process in which nucleotide sequence is translated to protein sequence whereby enzymes aminoacyl-tRNA synthetases play an important role in catalysis of aminoacyl-tRNA synthesis. During translation process, incorporation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::be9c898521362ee536a717f1acce329c
https://www.bib.irb.hr/1138198
https://www.bib.irb.hr/1138198