Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Evgeny V. Shchegolkov"'
Autor:
Galina F. Makhaeva, Nadezhda V. Kovaleva, Elena V. Rudakova, Natalia P. Boltneva, Maria V. Grishchenko, Sofya V. Lushchekina, Tatiana Y. Astakhova, Olga G. Serebryakova, Elena N. Timokhina, Ekaterina F. Zhilina, Evgeny V. Shchegolkov, Mariya V. Ulitko, Eugene V. Radchenko, Vladimir A. Palyulin, Yanina V. Burgart, Victor I. Saloutin, Sergey O. Bachurin, Rudy J. Richardson
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2285 (2023)
A series of previously synthesized conjugates of tacrine and salicylamide was extended by varying the structure of the salicylamide fragment and using salicylic aldehyde to synthesize salicylimine derivatives. The hybrids exhibited broad-spectrum bio
Externí odkaz:
https://doaj.org/article/7e0b27a3aeb244eeb22116b3b545edc1
Autor:
Yanina V. Burgart, Natalia A. Elkina, Evgeny V. Shchegolkov, Olga P. Krasnykh, Galina F. Makhaeva, Galina A. Triandafilova, Sergey Yu. Solodnikov, Natalia P. Boltneva, Elena V. Rudakova, Nadezhda V. Kovaleva, Olga G. Serebryakova, Mariya V. Ulitko, Sophia S. Borisevich, Natalia A. Gerasimova, Natalia P. Evstigneeva, Sergey A. Kozlov, Yuliya V. Korolkova, Artem S. Minin, Anna V. Belousova, Evgenii S. Mozhaitsev, Artem M. Klabukov, Victor I. Saloutin
Publikováno v:
Molecules, Vol 28, Iss 1, p 59 (2022)
4-Arylhydrazinylidene-5-(polyfluoroalkyl)pyrazol-3-ones (4-AHPs) were found to be obtained by the regiospecific cyclization of 2-arylhydrazinylidene-3-(polyfluoroalkyl)-3-oxoesters with hydrazines, by the azo coupling of 4-nonsubstituted pyrazol-5-ol
Externí odkaz:
https://doaj.org/article/e03f60e649344091824c96142959378b
Autor:
Yanina V. Burgart, Galina F. Makhaeva, Olga P. Krasnykh, Sophia S. Borisevich, Natalia A. Agafonova, Nadezhda V. Kovaleva, Natalia P. Boltneva, Elena V. Rudakova, Evgeny V. Shchegolkov, Galina A. Triandafilova, Denis A. Gazizov, Olga G. Serebryakova, Maria V. Ulitko, Sergey L. Khursan, Victor I. Saloutin, Rudy J. Richardson
Publikováno v:
Molecules, Vol 27, Iss 22, p 7722 (2022)
One of the powerful antioxidants used clinically is Edaravone (EDA). We synthesized a series of new EDA analogs, 4-aminopyrazol-5-ol hydrochlorides, including polyfluoroalkyl derivatives, via the reduction of 4-hydroxyiminopyrazol-5-ones. The primary
Externí odkaz:
https://doaj.org/article/3cd9c6dde8a64d83a9b45ad8db1476b6
Autor:
Natalia A. Elkina, Maria V. Grishchenko, Evgeny V. Shchegolkov, Galina F. Makhaeva, Nadezhda V. Kovaleva, Elena V. Rudakova, Natalia P. Boltneva, Sofya V. Lushchekina, Tatiana Y. Astakhova, Eugene V. Radchenko, Vladimir A. Palyulin, Ekaterina F. Zhilina, Anastasiya N. Perminova, Luka S. Lapshin, Yanina V. Burgart, Victor I. Saloutin, Rudy J. Richardson
Publikováno v:
Biomolecules, Vol 12, Iss 11, p 1551 (2022)
Alzheimer’s disease (AD) is considered a modern epidemic because of its increasing prevalence worldwide and serious medico-social consequences, including the economic burden of treatment and patient care. The development of new effective therapeuti
Externí odkaz:
https://doaj.org/article/407988391fe84cfd910efe4df0c33cf1
Autor:
Luka S. Lapshin, Evgeny V. Shchegolkov, Yanina V. Burgart, Galina A. Triandafilova, Olga P. Krasnykh, Kseniya O. Malysheva, Victor I. Saloutin
Publikováno v:
Mendeleev Communications. 33:194-196
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91b94bc66684f35fc15c5e233645b4da
https://doi.org/10.1016/j.mencom.2023.02.014
https://doi.org/10.1016/j.mencom.2023.02.014
Autor:
Olga G. Khudina, Yanina V. Burgart, Natalia A. Malkova, Evgeny V. Shchegolkov, Olga P. Krasnykh, Galina A. Triandafilova, Ksenia O. Malysheva, Sergey Yu. Solodnikov, Elisaveta S. Dubodel, Yuliya V. Korolkova, Sergey A. Kozlov, Sophia S. Borisevich, Evgenii S. Mozhaitsev, Victor I. Saloutin
Publikováno v:
ChemMedChem.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d1113aafe81dd61b514c150428491fe
https://doi.org/10.1002/cmdc.202300063
https://doi.org/10.1002/cmdc.202300063
Autor:
Evgeny V. Shchegolkov, Olga G. Serebryakova, Galina F. Makhaeva, Natalia A. Elkina, Ya. V. Burgart, Sofya V. Lushchekina, Viktor I. Saloutin, N. P. Boltneva
Publikováno v:
Russian Chemical Bulletin. 70:567-572
A series of new adamantyl and citronellyl 4,4,4-trifluoro-2-arylhydrazinylidene-3-oxo-butanoates was synthesized. The synthesized compounds in nanomolar concentrations selectively inhibit carboxylesterase, while their activity is independent of the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::659876c524b9c59621acd80abcbe35e1
https://doi.org/10.1007/s11172-021-3126-2
https://doi.org/10.1007/s11172-021-3126-2
Autor:
Maria V. Grishchenko, Galina F. Makhaeva, Yanina V. Burgart, Elena V. Rudakova, Natalia P. Boltneva, Nadezhda V. Kovaleva, Olga G. Serebryakova, Sofya V. Lushchekina, Tatiana Y. Astakhova, Ekaterina F. Zhilina, Evgeny V. Shchegolkov, Rudy J. Richardson, Victor I. Saloutin
Publikováno v:
ChemMedChem. 17
New conjugates of tacrine and salicylamide with alkylene spacers were synthesized and evaluated as potential multifunctional agents for Alzheimer's disease (AD). The compounds exhibited high acetylcholinesterase (AChE, IC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2d1ef0ee2484393f74ee3b8d1da2c4
https://doi.org/10.1002/cmdc.202200080
https://doi.org/10.1002/cmdc.202200080
Autor:
Evgeny V. Shchegolkov, Elena V. Rudakova, Olga G. Serebryakova, Victor I. Saloutin, Natalia А. Elkina, Yanina V. Burgart, Olga P. Krasnykh, Sergey Yu. Solodnikov, Galina F. Makhaeva, V. V. Maslova, Galina A. Triandafilova
Publikováno v:
Chemistry of Heterocyclic Compounds. 56:199-207
New pyrazolo[1,5-a]pyrimidinones functionalized with the tolylhydrazone fragment were obtained as a result of cyclization of 3-oxo-2-(tolylhydrazinylidene) esters with 3-aminopyrazoles. In this case, methyl- and trifluoromethyl-containing derivatives
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::927b0954a996dae84bf023514c929ab5
https://doi.org/10.1007/s10593-020-02652-1
https://doi.org/10.1007/s10593-020-02652-1
Publikováno v:
AIP Conference Proceedings.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7b83d01dce4619c0f9edc331cef00b7
https://doi.org/10.1063/5.0069229
https://doi.org/10.1063/5.0069229