Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Evgeny V. Pospelov"'
Publikováno v:
Molecules, Vol 25, Iss 16, p 3613 (2020)
An efficient asymmetric synthesis of GlaxoSmithKline’s potent PDE4 inhibitor was accomplished in eight steps from a catechol-derived nitroalkene. The key intermediate (3-acyloxymethyl-substituted 1,2-oxazine) was prepared in a straightforward manne
Externí odkaz:
https://doaj.org/article/006be05a8e17462888e0d1a4ece5f649
Publikováno v:
Advanced Synthesis & Catalysis. 364:2557-2564
Autor:
Ivan S. Golovanov, Anton V. Leonov, Vladislav K. Lesnikov, Evgeny V. Pospelov, Kirill V. Frolov, Alexander A. Korlyukov, Yulia V. Nelyubina, Valentin V. Novikov, Alexey Yu. Sukhorukov
Publikováno v:
Dalton transactions (Cambridge, England : 2003). 51(11)
4,6,10-Trihydroxy-1,4,6,10-tetraazaadamantane (TAAD) has been shown to form a stable Fe(IV) complex having a diamantane cage structure, in which the metal center is coordinated by three oxygen atoms of the deprotonated ligand. The complex was charact
Publikováno v:
Chemistry of nitro compounds and related nitrogen-oxygen systems.
Publikováno v:
Molecules, Vol 25, Iss 3613, p 3613 (2020)
Molecules
Volume 25
Issue 16
Molecules
Volume 25
Issue 16
An efficient asymmetric synthesis of GlaxoSmithKline&rsquo
s potent PDE4 inhibitor was accomplished in eight steps from a catechol-derived nitroalkene. The key intermediate (3-acyloxymethyl-substituted 1,2-oxazine) was prepared in a straightforw
s potent PDE4 inhibitor was accomplished in eight steps from a catechol-derived nitroalkene. The key intermediate (3-acyloxymethyl-substituted 1,2-oxazine) was prepared in a straightforw