Výsledky vyhledávání - "Evgeny M. Makarov"

Akademický článek

GENERIC COORDINATE SYSTEMS IN THE COMPUTER GEOMETRY COURSE

Autor: Evgeny M. Makarov

Publikováno v: Современные информационные технологии и IT-образование, Vol 14, Iss 4, Pp 833-841 (2018)

The article presents an approach to describe generic coordinate systems as a part of the course “Computer Geometry and Geometric Modeling”, which is taught to third-year students majoring in mathematics at the Lobachevsky State University of Nizh

Externí odkaz: https://doaj.org/article/fe957953eff743979be3284b421e835d

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Akademický článek

Human Properdin Modulates Macrophage: Mycobacterium bovis BCG Interaction via Thrombospondin Repeats 4 and 5

Autor: Maha Ahmed Al-Mozaini, Anthony G. Tsolaki, Munirah Abdul-Aziz, Suhair M. Abozaid, Mohammed N. Al-Ahdal, Ansar A. Pathan, Valarmathy Murugaiah, Evgeny M. Makarov, Anuvinder Kaur, Robert B. Sim, Uday Kishore, Lubna Kouser

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

Mycobacterium tuberculosis can proficiently enter macrophages and diminish complement activation on its cell surface. Within macrophages, the mycobacterium can suppress macrophage apoptosis and survive within the intracellular environment. Previously

Externí odkaz: https://doaj.org/article/36f7c38f819b4a6fbc5908bb3d060aa6

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Akademický článek

The rare nonsense mutation in p53 triggers alternative splicing to produce a protein capable of inducing apoptosis.

Autor: Evgeny M Makarov, Tatyana A Shtam, Roman A Kovalev, Rimma A Pantina, Elena Yu Varfolomeeva, Michael V Filatov

Publikováno v: PLoS ONE, Vol 12, Iss 9, p e0185126 (2017)

P53 protein is more frequently mutated in human tumours compared with the other proteins. While the majority of the p53 mutations, especially within its DNA-binding domain, lead to the loss of the wild-type function, there are accumulating data demon

Externí odkaz: https://doaj.org/article/20e072f7d1cd4fdf93dab958468fdb29

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MYC regulates metabolism through vesicular transfer of glycolytic kinases

Autor: Luisa Pieroni, Giuseppe Palmisano, Gianluca Sala, Martina Morini, Evon Poon, Arturo Sala, Louis Chesler, Alessandra Eva, Alexia Tsakaneli, Vincenzo De Laurenzi, Evgeny M. Makarov, Martin R. Larsen, Giuliana Cangemi, Sandra Bibbò, Emily Capone, Olesya Chayka, Victor Corasolla Carregari

Publikováno v: Tsakaneli, A, Carregari, V C, Morini, M, Eva, A, Cangemi, G, Chayka, O, Makarov, E, Bibbò, S, Capone, E, Sala, G, De Laurenzi, V, Poon, E, Chesler, L, Pieroni, L, Larsen, M R, Palmisano, G & Sala, A 2021, ' MYC regulates metabolism through vesicular transfer of glycolytic kinases ', Open Biology, vol. 11, no. 12, 210276 . https://doi.org/10.1098/rsob.210276
Open Biology
Open Biology, Vol 11, Iss 12 (2021)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Electronic supplementary material is available online at https://doi.org/10.6084/m9.figshare.c.5713034. Copyright © 2021 The Authors. Amplification of the proto-oncogene MYCN is a key molecular aberration in high-risk neuroblastoma and predictive of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa9b97ab242ebbd2923beab216db9653
https://findresearcher.sdu.dk:8443/ws/files/197558028/rsob.210276.pdf

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Akademický článek

The 35S U5 snRNP Is Generated from the Activated Spliceosome during In vitro Splicing.

Autor: Olga V Makarova, Evgeny M Makarov

Publikováno v: PLoS ONE, Vol 10, Iss 5, p e0128430 (2015)

Primary gene transcripts of eukaryotes contain introns, which are removed during processing by splicing machinery. Biochemical studies In vitro have identified a specific pathway in which introns are recognised and spliced out. This occurs by progres

Externí odkaz: https://doaj.org/article/2b92401b3e764fc18049e7d6aa77fb75

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Presence and distribution of progerin in HGPS cells is ameliorated by drugs that impact on the mevalonate and mTOR pathways

Autor: Ian R. Kill, Wendy Ofosu, Joanna M. Bridger, Craig S. Clements, Evgeny M. Makarov, David Tree, Christopher H. Eskiw, Mehmet U. Bikkul

Publikováno v: Biogerontology

Hutchinson–Gilford progeria syndrome (HGPS) is a rare, premature ageing syndrome in children. HGPS is normally caused by a mutation in the LMNA gene, encoding nuclear lamin A. The classical mutation in HGPS leads to the production of a toxic trunca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6b2fd09330521c2ec71ca71051a6af
http://europepmc.org/articles/PMC6535420

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Exosomes Transfer p53 between Cells and Can Suppress Growth and Proliferation of p53-Negative Cells

Autor: Evgeny M. Makarov, E. Yu. Varfolomeeva, R. A. Kovalev, Michael V. Filatov, R. A. Pantina, Vladimir Burdakov

Publikováno v: Cell and Tissue Biology. 12:20-26

Exosomes are nanosized vesicles that are secreted by many types of cells. We have found that exosomes secreted by HEK293 and HT-1080 can suppress growth and proliferation of p53-deficient cells. Upon overexpression of exogenous p53-GFP in HEK293 cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6694a274384975ecb999e2deaaf32289
https://doi.org/10.1134/s1990519x18010030

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Akademický článek

Isoforms of U1-70k control subunit dynamics in the human spliceosomal U1 snRNP.

Autor: Helena Hernández, Olga V Makarova, Evgeny M Makarov, Nina Morgner, Yutaka Muto, Daniel Pomeranz Krummel, Carol V Robinson

Publikováno v: PLoS ONE, Vol 4, Iss 9, p e7202 (2009)

Most human protein-encoding genes contain multiple exons that are spliced together, frequently in alternative arrangements, by the spliceosome. It is established that U1 snRNP is an essential component of the spliceosome, in human consisting of RNA a

Externí odkaz: https://doaj.org/article/7a58c3b07cf4409ba14d0db75c0593ea

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