Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Evgeny L. Gulyak"'
Publikováno v:
Molecules, Vol 28, Iss 23, p 7890 (2023)
Antibodies and their derivatives (scFv, Fabs, etc.) represent a unique class of biomolecules that combine selectivity with the ability to target drug delivery. Currently, one of the most promising endeavors in this field is the development of molecul
Externí odkaz:
https://doaj.org/article/335877803aae41978d5a31dffbb0cf66
Autor:
Igor E. Mikhnovets, Jiří Holoubek, Irina S. Panina, Jan Kotouček, Daniil A. Gvozdev, Stepan P. Chumakov, Maxim S. Krasilnikov, Mikhail Y. Zhitlov, Evgeny L. Gulyak, Alexey A. Chistov, Timofei D. Nikitin, Vladimir A. Korshun, Roman G. Efremov, Vera A. Alferova, Daniel Růžek, Luděk Eyer, Alexey V. Ustinov
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16483 (2023)
Amphipathic perylene derivatives are broad-spectrum antivirals against enveloped viruses that act as fusion inhibitors in a light-dependent manner. The compounds target the lipid bilayer of the viral envelope using the lipophilic perylene moiety and
Externí odkaz:
https://doaj.org/article/bda4991d6ffd48c897d5b76aae98ae10
Autor:
Ksenia A. Sapozhnikova, Evgeny L. Gulyak, Vladimir A. Brylev, Vsevolod A. Misyurin, Sergey D. Oreshkov, Anastasiya V. Alexeeva, Dmitry Yu. Ryazantsev, Maria A. Simonova, Ekaterina V. Ryabukhina, Galina P. Popova, Nataliya A. Tikhonova, Natalia A. Lyzhko, Alexander E. Barmashov, Andrey V. Misyurin, Alexey V. Ustinov, Vera A. Alferova, Vladimir A. Korshun
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5134 (2023)
A universal approach to the construction of antibody–drug conjugates (ADCs) has been developed. It relies on periodate oxidation of naturally present glycans of immunoglobulin G, followed by oxime ligation and, optionally, copper(I)-catalyzed alkyn
Externí odkaz:
https://doaj.org/article/b5bf2e59e5af49ff868a1ecc3e741f27
Autor:
Ksenia A. Sapozhnikova, Evgeny L. Gulyak, Vsevolod A. Misyurin, Maria A. Simonova, Ekaterina V. Ryabukhina, Anastasiya V. Alexeeva, Nataliya A. Tikhonova, Natalia A. Lyzhko, Galina P. Popova, Andrey V. Misyurin, Alexey V. Ustinov, Vladimir A. Korshun, Vera A. Alferova, Dmitry Yu. Ryazantsev, Vladimir A. Brylev
Publikováno v:
Molecules, Vol 28, Iss 1, p 425 (2023)
Fluorescent antibodies have proved to be an invaluable tool for molecular biology and diagnostics. They are routinely produced by modification of lysine residues, which leads to high heterogeneity. As such, their affinity may be compromised if the an
Externí odkaz:
https://doaj.org/article/b462062bf3f444a6a6792430f6e3c587
Autor:
Matvey V. Fedin, Alexander A. Lomzov, Victor M. Tormyshev, Dmitrii V. Pyshnyi, Georgiy Yu. Shevelev, Maxim S. Kupryushkin, Olesya A. Krumkacheva, Evgeny L. Gulyak, Andrey A. Kuzhelev, Elena G. Bagryanskaya
Publikováno v:
The Journal of Physical Chemistry B. 122:137-143
Triarylmethyl (trityl, TAM) radicals are a promising class of spin labels for nanometer-scale distance measurements in biomolecules at physiological temperatures. However, to date, existing approaches to site-directed TAM labeling of DNA have been li