Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Evgeny Deforzh"'
Autor:
Yanhong Zhang, Rosalia Rabinovsky, Zhiyun Wei, Rachid El Fatimy, Evgeny Deforzh, Bai Luan, Leonid Peshkin, Erik J. Uhlmann, Anna M. Krichevsky
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 265-275 (2023)
MicroRNA-10b (miR-10b) is an essential glioma driver and one of the top candidates for targeted therapies for glioblastoma and other cancers. This unique miRNA controls glioma cell cycle and viability via an array of established conventional and unco
Externí odkaz:
https://doaj.org/article/10a4b48db9e44e428e91f68ba2b1e1e6
Autor:
Rachid El Fatimy, Yanhong Zhang, Evgeny Deforzh, Mahalakshmi Ramadas, Harini Saravanan, Zhiyun Wei, Rosalia Rabinovsky, Nadiya M. Teplyuk, Erik J. Uhlmann, Anna M. Krichevsky
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-19 (2022)
Abstract Background miRNAs are regulatory transcripts established as repressors of mRNA stability and translation that have been functionally implicated in carcinogenesis. miR-10b is one of the key onco-miRs associated with multiple forms of cancer.
Externí odkaz:
https://doaj.org/article/f937b4f91e9b476aa787c3a706e91a6a
Autor:
Ailiang Zeng, Zhiyun Wei, Rosalia Rabinovsky, Hyun Jung Jun, Rachid El Fatimy, Evgeny Deforzh, Ramil Arora, Yizheng Yao, Shun Yao, Wei Yan, Erik J. Uhlmann, Alain Charest, Yongping You, Anna M. Krichevsky
Publikováno v:
iScience, Vol 23, Iss 8, Pp 101420- (2020)
Summary: Glioblastoma (GBM) may arise from astrocytes through a multistep process involving a progressive accumulation of mutations. We explored whether GBM-derived extracellular vesicles (EVs) may facilitate neoplastic transformation and malignant g
Externí odkaz:
https://doaj.org/article/affd28779865474595993f92557b0b03
Autor:
Erik J. Uhlmann, Charles E. Mackel, Evgeny Deforzh, Rosalia Rabinovsky, Priscilla K. Brastianos, Hemant Varma, Rafael A. Vega, Anna M. Krichevsky
Publikováno v:
Journal of Neuro-Oncology. 162:109-118
Purpose Meningioma is the most common primary central nervous system tumor often causing serious complications, and presently no medical treatment is available. The goal of this study was to discover miRNAs dysregulated in meningioma, and explore miR
Autor:
Evgeny Deforzh, Erik J. Uhlmann, Eashita Das, Aleksandra Galitsyna, Ramil Arora, Harini Saravanan, Rosalia Rabinovsky, Aditya D. Wirawan, Nadiya M. Teplyuk, Rachid El Fatimy, Sucika Perumalla, Anirudh Jairam, Zhiyun Wei, Leonid Mirny, Anna M. Krichevsky
Publikováno v:
Mol Cell
miR-10b is silenced in normal neuroglial cells of the brain but commonly activated in glioma, where it assumes an essential tumor-promoting role. We demonstrate that the entire miR-10b-hosting HOXD locus is activated in glioma via the cis-acting mech
Autor:
Wei Yan, Shun Yao, Zhiyun Wei, Rosalia Rabinovsky, Ramil Arora, Yizheng Yao, Anna M. Krichevsky, Alain Charest, Hyun Jung Jun, Evgeny Deforzh, Ailiang Zeng, Erik J. Uhlmann, Yongping You, Rachid El Fatimy
Publikováno v:
iScience, Vol 23, Iss 8, Pp 101420-(2020)
iScience
iScience
Summary Glioblastoma (GBM) may arise from astrocytes through a multistep process involving a progressive accumulation of mutations. We explored whether GBM-derived extracellular vesicles (EVs) may facilitate neoplastic transformation and malignant gr
Autor:
Jeremie Kropp, Anna Polesskaya, Evgeny Deforzh, Marie Vandamme, Thaiz Rivera Vargas, Guillaume Pinna
Publikováno v:
International Journal of Oncology
International Journal of Oncology, Spandidos Publications, 2016, 〈https://www.spandidos-publications.com/ijo/49/6/2578〉. 〈10.3892/ijo.2016.3750〉
International Journal of Oncology, Spandidos Publications, 2016, ⟨10.3892/ijo.2016.3750⟩
International Journal of Oncology, 2016, ⟨10.3892/ijo.2016.3750⟩
International Journal of Oncology, Spandidos Publications, 2016, 〈https://www.spandidos-publications.com/ijo/49/6/2578〉. 〈10.3892/ijo.2016.3750〉
International Journal of Oncology, Spandidos Publications, 2016, ⟨10.3892/ijo.2016.3750⟩
International Journal of Oncology, 2016, ⟨10.3892/ijo.2016.3750⟩
International audience; IGF-2 mRNA binding protein 3 (IGF2BP3, IMP-3) is a well-known post-transcriptional regulatory factor of gene expression, mainly involved in embryonic development and oncogenesis. We have previously demonstrated that a subset o
Autor:
Regina Groisman, Linda L. Pritchard, Annick Harel-Bellan, Cindy Degerny, Sylvain Cuvellier, Evgeny Deforzh, Andrii Vislovukh, Irina Groisman, Gueorgui Kratassiouk, Qingwei Meng
Publikováno v:
Cell Cycle
Cell Cycle, Taylor & Francis, 2016, 15 (5), pp.667-677. ⟨10.1080/15384101.2016.1147631⟩
Cell Cycle, Taylor & Francis, 2016, 15 (5), pp.667-677. 〈10.1080/15384101.2016.1147631〉
Cell Cycle, 2016, 15 (5), pp.667-677. ⟨10.1080/15384101.2016.1147631⟩
Cell Cycle, Taylor & Francis, 2016, 15 (5), pp.667-677. ⟨10.1080/15384101.2016.1147631⟩
Cell Cycle, Taylor & Francis, 2016, 15 (5), pp.667-677. 〈10.1080/15384101.2016.1147631〉
Cell Cycle, 2016, 15 (5), pp.667-677. ⟨10.1080/15384101.2016.1147631⟩
International audience; MicroRNAs (miRNAs) in the AGO-containing RISC complex control messenger RNA (mRNA) translation by binding to mRNA 3' untranslated region (3'UTR). The relationship between miRNAs and other regulatory factors that also bind to m