Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Evgeny Chirshev"'
Autor:
Evgeny Chirshev, Nozomi Hojo, Antonella Bertucci, Linda Sanderman, Anthony Nguyen, Hanmin Wang, Tise Suzuki, Emmanuel Brito, Shannalee R. Martinez, Christine Castañón, Saied Mirshahidi, Marcelo E. Vazquez, Pamela Wat, Kerby C. Oberg, Yevgeniya J. Ioffe, Juli J. Unternaehrer
Publikováno v:
Molecular Oncology, Vol 14, Iss 11, Pp 2796-2813 (2020)
Patient‐derived samples present an advantage over current cell line models of high‐grade serous ovarian cancer (HGSOC) that are not always reliable and phenotypically faithful models of in vivo HGSOC. To improve upon cell line models of HGSOC, we
Externí odkaz:
https://doaj.org/article/138a47b5f6b14158afe2edeb9b06b17b
Autor:
Hossam R. Alkashgari, Caleb Ruiz-Jimenez, Cornelia Stoian, Jacqueline S. Coats, Ineavely Baez, Evgeny Chirshev, Shannalee R. Martinez, Sinisa Dovat, Olivia L. Francis-Boyle, Carlos A. Casiano, Kimberly J. Payne
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 474 (2022)
Cytokine receptor-like factor 2 B-cell acute lymphoblastic leukemia (CRLF2 B-ALL) is a high-risk subtype characterized by CRLF2 overexpression with poor survival rates in children and adults. CRLF2 and interleukin-7 receptor alpha (IL-7Rα) form a re
Externí odkaz:
https://doaj.org/article/62c41a9b905246ed8b1a057a2b72b10e
Publikováno v:
Clinical and Translational Medicine, Vol 8, Iss 1, Pp 1-14 (2019)
Abstract Abnormal regulation and expression of microRNAs (miRNAs) has been documented in various diseases including cancer. The miRNA let-7 (MIRLET7) family controls developmental timing and differentiation. Let-7 loss contributes to carcinogenesis v
Externí odkaz:
https://doaj.org/article/9111acd390f04dd99f5304c8768edd33
Autor:
Qizhi Liu, Stacey Chung, Michael M. Murata, Bingchen Han, Bowen Gao, Maoqi Zhang, Tian-Yu Lee, Evgeny Chirshev, Juli Unternaehrer, Hisashi Tanaka, Armando E. Giuliano, Yukun Cui, Xiaojiang Cui
Publikováno v:
International journal of biological sciences. 18(10)
Autor:
Linda Sanderman, Nozomi Hojo, Yevgeniya Ioffe, Tise Suzuki, Evgeny Chirshev, Hanmin Wang, Juli Unternaehrer, Anthony L. Nguyen, Saied Mirshahidi
Publikováno v:
Cancers
Volume 13
Issue 18
Cancers, Vol 13, Iss 4617, p 4617 (2021)
Volume 13
Issue 18
Cancers, Vol 13, Iss 4617, p 4617 (2021)
Simple Summary Ovarian cancer has a dismal prognosis and innovative treatment options are necessary to improve survival. Because the microRNA let-7 is often lost in this and other cancers, and its loss is associated with poor prognosis, we focused on
Autor:
Antonella Bertucci, Hanmin Wang, Tise Suzuki, Jeffrey I. Zink, Carlotta A. Glackin, Yevgeniya Ioffe, Juli Unternaehrer, Michael Pierce, Ruining Wang, Evgeny Chirshev, Nozomi Hojo, Chris T. Perry
Publikováno v:
Cancers, Vol 13, Iss 1469, p 1469 (2021)
Cancers
Volume 13
Issue 6
Cancers
Volume 13
Issue 6
We aimed to determine the mechanism of epithelial-mesenchymal transition (EMT)-induced stemness in cancer cells. Cancer relapse and metastasis are caused by rare stem-like cells within tumors. Studies of stem cell reprogramming have linked let-7 repr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20bc973d62a145b557589d785254cae3
https://doi.org/10.1101/2020.11.04.368688
https://doi.org/10.1101/2020.11.04.368688
Autor:
Tise Suzuki, Evgeny Chirshev, Linda Sanderman, Pamela Wat, Kerby C. Oberg, Hanmin Wang, Antonella Bertucci, Juli Unternaehrer, Christine Castañón, Anthony L. Nguyen, Yevgeniya Ioffe, Shannalee R. Martinez, Emmanuel Brito, Saied Mirshahidi, Marcelo Vazquez, Nozomi Hojo
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 14, Iss 11, Pp 2796-2813 (2020)
Molecular Oncology, Vol 14, Iss 11, Pp 2796-2813 (2020)
We studied ovarian cancer patient‐derived cells to determine their epithelial vs. mesenchymal phenotype, and their stemness, migration, invasion, and tumor growth characteristics. Surprisingly, stemness could be dissociated from invasiveness. We ob
Publikováno v:
Clinical and Translational Medicine
Clinical and Translational Medicine, Vol 8, Iss 1, Pp 1-14 (2019)
Clinical and Translational Medicine, Vol 8, Iss 1, Pp 1-14 (2019)
Abnormal regulation and expression of microRNAs (miRNAs) has been documented in various diseases including cancer. The miRNA let-7 (MIRLET7) family controls developmental timing and differentiation. Let-7 loss contributes to carcinogenesis via an inc
Autor:
Kerby C. Oberg, Marcelo Vazquez, Hanmin Wang, Antonella Bertucci, Tise Suzuki, Emmanuel Brito, Saied Mirshahidi, Shannalee Martine, Christine Castañón, Nozomi Hojo, Anthony L. Nguyen, Evgeny Chirshev, Juli Unternaehrer, Yevgeniya Ioffe, Linda Sanderman
Publikováno v:
Cancer Research. 80:1682-1682
Objective: Patient-derived samples present an advantage over current cell line models of high grade serous ovarian cancer (HGSOC), which are flawed in terms of being reliable and phenotypically faithful models of in vivo HGSOC. To improve upon cell l
Publikováno v:
Clinical Cancer Research. 25:TMIM-065
INTRODUCTION: Epithelial ovarian cancer (EOC) is the fifth deadliest malignancy in women in the United States, with a high death-to-incidence ratio and five-year survival of 30%. Aggressiveness and recurrence of EOC has been attributed to cancer stem