Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Evgeny Berdyshev"'
Autor:
Manjula Karpurapu, Yunjuan Nie, Sangwoon Chung, Jiasheng Yan, Patrick Dougherty, Sonal Pannu, Jon Wisler, Ryan Harkless, Narasimham Parinandi, Evgeny Berdyshev, Dehua Pei, John W. Christman
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Extracellular vesicles mediate intercellular communication by transporting biologically active macromolecules. Our prior studies have demonstrated that the nuclear factor of activated T cell cytoplasmic member 3 (NFATc3) is activated in mouse pulmona
Externí odkaz:
https://doaj.org/article/e4c82b57f47e4bf2a0bcb4bf10e5e08e
Autor:
Byung Eui Kim, Jihyun Kim, Elena Goleva, Evgeny Berdyshev, Jinyoung Lee, Kathryn A. Vang, Un Ha Lee, SongYi Han, Susan Leung, Clifton F. Hall, Na-Rae Kim, Irina Bronova, Eu Jin Lee, Hye-Ran Yang, Donald Y.M. Leung, Kangmo Ahn
Publikováno v:
JCI Insight, Vol 6, Iss 5 (2021)
The molecular mechanisms that underlie the detrimental effects of particulate matter (PM) on skin barrier function are poorly understood. In this study, the effects of PM2.5 on filaggrin (FLG) and skin barrier function were investigated in vitro and
Externí odkaz:
https://doaj.org/article/4d6342e3fcc34ccd84edee348430aa91
Autor:
Samantha Genardi, Lavanya Visvabharathy, Liang Cao, Eva Morgun, Yongyong Cui, Chao Qi, Yi-Hua Chen, Laurent Gapin, Evgeny Berdyshev, Chyung-Ru Wang
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Methicillin-resistant Staphylococcus aureus (SA) bacteremia is responsible for over 10,000 deaths in the hospital setting each year. Both conventional CD4+ T cells and γδ T cells play protective roles in SA infection through secretion of IFN-γ and
Externí odkaz:
https://doaj.org/article/4738979384d84047be2f0c52342e0eee
Autor:
Lavanya Visvabharathy, Samantha Genardi, Liang Cao, Ying He, Francis Alonzo, Evgeny Berdyshev, Chyung-Ru Wang
Publikováno v:
PLoS Pathogens, Vol 16, Iss 4, p e1008443 (2020)
Staphylococcus aureus (SA) is the causative agent of both skin/soft tissue infections as well as invasive bloodstream infections. Though vaccines have been developed to target both humoral and T cell-mediated immune responses against SA, they have la
Externí odkaz:
https://doaj.org/article/b57ecb31b2ca48d48fc36cf068858a2f
Autor:
Myung-Jin Oh, Chongxu Zhang, Elizabeth LeMaster, Crystal Adamos, Evgeny Berdyshev, Yedida Bogachkov, Erin E. Kohler, Jugajyoti Baruah, Yun Fang, Dean E. Schraufnagel, Kishore K. Wary, Irena Levitan
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 5, Pp 791-808 (2016)
Endothelial biomechanics is emerging as a key factor in endothelial function. Here, we address the mechanisms of endothelial stiffening induced by oxidized LDL (oxLDL) and investigate the role of oxLDL in lumen formation. We show that oxLDL-induced e
Externí odkaz:
https://doaj.org/article/6483c693e19b4ae58ce7388fa48fa1ab
Autor:
Nigel J. Pyne, Susan Pyne, David G. Watson, Robert Bittman, Evgeny Berdyshev, Irina Gorshkova, Francesca Tonelli, Viswanathan Natarajan, Manal Alossaimi
Publikováno v:
Biomolecules, Vol 3, Iss 2, Pp 316-333 (2013)
We have previously shown that treatment of androgen-sensitive LNCaP cells with the sphingosine kinase (SK) inhibitor SKi (2-(p-hydroxyanilino)-4-(p-chlorophenyl)thiazole) induces the proteasomal degradation of two N-terminal variants of SK1 (SK1a and
Externí odkaz:
https://doaj.org/article/a246bb63785c461c9259b124ddc26ac9
Autor:
Chun Jerold, Evgeny Berdyshev, Pendyala Srikanth, He Donghong, Tong Jiankun, Zhao Yutong, Sperling Anne I, Natarajan Viswanathan
Publikováno v:
Respiratory Research, Vol 10, Iss 1, p 114 (2009)
Abstract Background Lysophosphatidic acid (LPA) plays a critical role in airway inflammation through G protein-coupled LPA receptors (LPA1-3). We have demonstrated that LPA induced cytokine and lipid mediator release in human bronchial epithelial cel
Externí odkaz:
https://doaj.org/article/16a028a020d24c57aa1434adde2bec0f
Autor:
Evgeny Berdyshev, Jihyun Kim, Byung Eui Kim, Elena Goleva, Taras Lyubchenko, Irina Bronova, Anna Sofia Bronoff, Olivia Xiao, Jiwon Kim, Sukyung Kim, Mijeong Kwon, Sungjoo Lee, Yu Jeong Seo, Kyunga Kim, Suk-Joo Choi, Soo-Young Oh, Seung Hwan Kim, So Yeon Yu, Seung Yong Hwang, Kangmo Ahn, Donald Y.M. Leung
Publikováno v:
Journal of Allergy and Clinical Immunology. 151:1307-1316
Publikováno v:
Journal of Allergy and Clinical Immunology. 151:26-28
Atopic dermatitis (AD) and food allergy (FA) are strongly associated, with one-third of children with AD developing concomitant FA. Epithelial barrier dysfunction is important in both conditions. Genetic factors, such as filaggrin mutations and IL-4
Autor:
Evgeny Berdyshev, Elena Goleva, Robert Bissonnette, Irina Bronova, Anna Sofia Bronoff, Brittany N. Richers, Shannon Garcia, Marco Ramirez‐Gama, Patricia Taylor, Amy Praestgaard, Inoncent Agueusop, Pauline Jurvilliers, Mark Boguniewicz, Noah A. Levit, Ana B. Rossi, Annie Zhang, Donald Y. M. Leung
Publikováno v:
Allergy. 77:3388-3397
Atopic dermatitis (AD) is characterized by abnormal skin lipids that are largely driven by hyperactivated type 2 immune responses. The antibody to the α-subunit of interleukin (IL)-4 receptor, dupilumab, was recently approved to treat AD and demonst