Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Evgeniy R Galimov"'
Autor:
Stephen J Brett, Vishal Patel, Sophie Young, Bethany Levick, Daniel C Gibbons, Tahereh Kamalati, Myriam Drysdale, Evgeniy R Galimov, Marcus James Yarwood, Jonathan D Watkins, Benjamin F Pierce, Emily J Lloyd, William Kerr, Helen J Birch
Publikováno v:
BMJ Open Respiratory Research, Vol 11, Iss 1 (2024)
Background We assessed the effectiveness of sotrovimab vs no early COVID-19 treatment in highest-risk COVID-19 patients during Omicron predominance.Methods Retrospective cohort study using the Discover dataset in North West London. Included patients
Externí odkaz:
https://doaj.org/article/63c9ad243a8c40aca8bd08c0e7ef1fac
Autor:
Hongyuan Wang, Yuan Zhao, Marina Ezcurra, Alexandre Benedetto, Ann F. Gilliat, Josephine Hellberg, Ziyu Ren, Evgeniy R. Galimov, Trin Athigapanich, Johannes Girstmair, Maximilian J. Telford, Colin T. Dolphin, Zhizhou Zhang, David Gems
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 4, Iss 1, Pp 1-12 (2018)
Aging: Runaway programs are a cause of aging The main cause of disease worldwide is aging, a process long suspected to result from damage accumulation. However, new work from a team led by David Gems at University College London describes a different
Externí odkaz:
https://doaj.org/article/3519f894f35745668a4fd12ca37efb50
Autor:
Evgeniy R. Galimov, Rosina E. Pryor, Sarah E. Poole, Alexandre Benedetto, Zachary Pincus, David Gems
Publikováno v:
Cell Reports, Vol 22, Iss 10, Pp 2730-2741 (2018)
Summary: Organismal death is a process of systemic collapse whose mechanisms are less well understood than those of cell death. We previously reported that death in C. elegans is accompanied by a calcium-propagated wave of intestinal necrosis, marked
Externí odkaz:
https://doaj.org/article/c600758ff81a4a5a8801f350cb0c9c7b
Autor:
Faria Athar, Hannah Chapman, Yuan Zhao, Evgeniy R. Galimov, Bruce Zhang, David Gems, Hongyuan Wang, Ioan Marcu
Publikováno v:
Aging Cell
In aging Caenorhabditis elegans, as in higher organisms, there is more than one cause of death. C. elegans exhibit early death with a swollen, infected pharynx (P death), and later death with pharyngeal atrophy (p death). Interventions that alter lif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c61f3d70457af4450745dab246998bdd
https://doi.org/10.1111/acel.13324
https://doi.org/10.1111/acel.13324
Autor:
David Gems, Evgeniy R. Galimov
Publikováno v:
Aging Cell
In the nematode Caenorhabditis elegans, loss of function of many genes leads to increases in lifespan, sometimes of a very large magnitude. Could this reflect the occurrence of programmed death that, like apoptosis of cells, promotes fitness? The not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e7b739725dfa087ee614f0828f3b65
https://doi.org/10.1111/acel.13141
https://doi.org/10.1111/acel.13141
Publikováno v:
Biochemistry. Biokhimiia. 84(12)
The concept of phenoptosis (or programmed organismal death) is problematic with respect to most species (including humans) since it implies that dying of old age is an adaptation, which contradicts the established evolutionary theory. But can dying e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1170380aafe18950679eed4ecc2a3fa
https://pubmed.ncbi.nlm.nih.gov/31870247
https://pubmed.ncbi.nlm.nih.gov/31870247
Autor:
Jack W, Rutter, Tanel, Ozdemir, Evgeniy R, Galimov, Leonor M, Quintaneiro, Luca, Rosa, Geraint M, Thomas, Filipe, Cabreiro, Chris P, Barnes
Publikováno v:
ACS synthetic biology. 8(12)
[Image: see text] Caenorhabditis elegans has become a key model organism within biology. In particular, the transparent gut, rapid growing time, and ability to create a defined gut microbiota make it an ideal candidate organism for understanding and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::adfd423445552937cd005462fe1d9d8d
https://pubmed.ncbi.nlm.nih.gov/31657907
https://pubmed.ncbi.nlm.nih.gov/31657907
Autor:
Geraint M.H. Thomas, Filipe Cabreiro, Evgeniy R. Galimov, Leonor M. Quintaneiro, Luca Rosa, Chris P. Barnes, Jack W. Rutter, Tanel Ozdemir
Caenorhabditis elegans has become a key model organism within biology. In particular, the transparent gut, rapid growing time, and ability to create a defined gut microbiota make it an ideal candidate organism for understanding and engineering the ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acbdaf698e914f1771d1406fb90a4126
http://hdl.handle.net/10044/1/76574
http://hdl.handle.net/10044/1/76574
Autor:
Evgeniy R. Galimov, David Gems
Publikováno v:
Philos Trans R Soc Lond B Biol Sci
Standard evolutionary theory, supported by mathematical modelling of outbred, dispersed populations predicts that ageing is not an adaptation. We recently argued that in clonal, viscous populations, programmed organismal death could promote fitness t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::404e7404ce5ed83d9135a22cbad7b4a2
https://doi.org/10.1098/rstb.2019.0730
https://doi.org/10.1098/rstb.2019.0730
Autor:
Cassandra Backes, Tobias von der Haar, Tristan Espie--Caullet, Evgeniy R. Galimov, Celia Lujan, Saul Moore, Victoria Eugenia Martinez-Miguel, Daniel Martinez-Martinez, Suam Gonzalez, Charalampos Rallis, Mario Halic, Filipe Cabreiro, Kazunori Tomita, Ivana Bjedov, André Ex Brown
Publikováno v:
Cell Metabolism
Mol Cell
2300.e12
Mol Cell
2300.e12
Summary Loss of proteostasis is a fundamental process driving aging. Proteostasis is affected by the accuracy of translation, yet the physiological consequence of having fewer protein synthesis errors during multi-cellular organismal aging is poorly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f87cc19ede7b78f7f37c50ba9a7cd40
http://europepmc.org/articles/PMC8570412
http://europepmc.org/articles/PMC8570412