Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Evgenia, Fadzeyeva"'
Autor:
Evgenia Fadzeyeva, Cassandra A.A. Locatelli, Natasha A. Trzaskalski, My-Anh Nguyen, Megan E. Capozzi, Branka Vulesevic, Nadya M. Morrow, Peyman Ghorbani, Antonio A. Hanson, Ilka Lorenzen-Schmidt, Mary-Anne Doyle, Richard Seymour, Elodie M. Varin, Morgan D. Fullerton, Jonathan E. Campbell, Erin E. Mulvihill
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106748- (2023)
Summary: Mice systemically lacking dipeptidyl peptidase-4 (DPP4) have improved islet health, glucoregulation, and reduced obesity with high-fat diet (HFD) feeding compared to wild-type mice. Some, but not all, of this improvement can be linked to the
Externí odkaz:
https://doaj.org/article/213537b074c74de6ba1a3b4427a6b586
Autor:
Natasha A. Trzaskalski, Branka Vulesevic, My-Anh Nguyen, Natasha Jeraj, Evgenia Fadzeyeva, Nadya M. Morrow, Cassandra A.A. Locatelli, Nicole Travis, Antonio A. Hanson, Julia R.C. Nunes, Conor O’Dwyer, Jelske N. van der Veen, Ilka Lorenzen-Schmidt, Rick Seymour, Serena M. Pulente, Andrew C. Clément, Angela M. Crawley, René L. Jacobs, Mary-Anne Doyle, Curtis L. Cooper, Kyoung-Han Kim, Morgan D. Fullerton, Erin E. Mulvihill
Publikováno v:
JCI Insight, Vol 8, Iss 2 (2023)
Elevated circulating dipeptidyl peptidase-4 (DPP4) is a biomarker for liver disease, but its involvement in gluconeogenesis and metabolic associated fatty liver disease progression remains unclear. Here, we identified that DPP4 in hepatocytes but not
Externí odkaz:
https://doaj.org/article/40cdcc7f6d5742ecbe16d60323de171c
Autor:
Yves Mugabo, Cheng Zhao, Ju Jing Tan, Anindya Ghosh, Scott A. Campbell, Evgenia Fadzeyeva, Frédéric Paré, Siew Siew Pan, Maria Galipeau, Julia Ast, Johannes Broichhagen, David J. Hodson, Erin E. Mulvihill, Sophie Petropoulos, Gareth E. Lim
Publikováno v:
JCI Insight, Vol 7, Iss 8 (2022)
While critical for neurotransmitter synthesis, 14-3-3 proteins are often assumed to have redundant functions due to their ubiquitous expression, but despite this assumption, various 14-3-3 isoforms have been implicated in regulating metabolism. We pr
Externí odkaz:
https://doaj.org/article/a212201235ad4383a3067ba2c4ddbc78
Publikováno v:
Clinical Medicine Insights: Endocrinology and Diabetes, Vol 13 (2020)
Dipeptidyl peptidase-4 (DPP4) is a serine protease that rapidly inactivates the incretin peptides, glucagon-like peptide-1, and glucose-dependent insulinotropic polypeptide to modulate postprandial islet hormone secretion and glycemia. Dipeptidyl pep
Externí odkaz:
https://doaj.org/article/cc3cb34db4cb42b091349b412005eec5
Autor:
Nadya M. Morrow, Natasha A. Trzaskalski, Antonio A. Hanson, Evgenia Fadzeyeva, Dawn E. Telford, Sanjiv S. Chhoker, Brian G. Sutherland, Jane Y. Edwards, Murray W. Huff, Erin E. Mulvihill
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42:127-144
Objective: Nobiletin is a dietary flavonoid that improves insulin resistance and atherosclerosis in mice with metabolic dysfunction. Dysregulation of intestinal lipoprotein metabolism contributes to atherogenesis. The objective of the study was to de
Autor:
Natasha A, Trzaskalski, Branka, Vulesevic, My-Anh, Nguyen, Natasha, Jeraj, Evgenia, Fadzeyeva, Nadya M, Morrow, Cassandra Aa, Locatelli, Nicole, Travis, Antonio A, Hanson, Julia Rc, Nunes, Conor, O'Dwyer, Jelske N, Van der Veen, Ilka, Lorenzen-Schmidt, Rick, Seymour, Serena M, Pulente, Andrew C, Clément, Angela M, Crawley, René L, Jacobs, Mary-Anne, Doyle, Curtis L, Cooper, Kyoung-Han, Kim, Morgan D, Fullerton, Erin E, Mulvihill
Publikováno v:
JCI insight.
Elevated circulating dipeptidyl-peptidase 4 is a biomarker for liver disease, but its involvement in gluconeogenesis and in metabolic-associated fatty liver disease (MAFLD) progression remains unclear. Here we identified that DPP4 in hepatocytes but
Autor:
Myriam Hoyeck, Evgenia Fadzeyeva, Dahai Zhang, James Lyon, Nancy Smith, Erin Mulvihill, Francis Lynn, Jocelyn Manning Fox, Patrick Macdonald, Jennifer Bruin
Publikováno v:
Canadian Journal of Diabetes. 46:S16
Autor:
Lahari Basu, Andrea Smith, Kayleigh Rick, Myriam Hoyeck, Evgenia Fadzeyeva, Erin Mulvihill, Jan Mennigen, Jennifer Bruin
Publikováno v:
Canadian Journal of Diabetes. 46:S30
Autor:
Yves Mugabo, Ryszard Grygorczyk, Gareth E. Lim, Ju Jing Tan, Maria Galipeau, Evgenia Fadzeyeva
Publikováno v:
Diabetes. 69
Pancreatic β-cells continuously sense blood glucose levels and secrete insulin to maintain normoglycemia. In β-cells, ATP generated by glycolysis promotes the closure of ATP-sensitive K+ channels, thereby increasing intracellular calcium and ultima
Autor:
Cassandra A A Locatelli, Erin E. Mulvihill, Natasha Trzaskalski, Evgenia Fadzeyeva, My-Ahn Nguyen
Publikováno v:
Canadian Journal of Diabetes. 45:S10