Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Evgeni Tzvetkov"'
Autor:
Thomas Clarke, Pan Du, Satyendra Kumar, Shinji L. Okitsu, Mark Schuette, Qi An, Jinyang Zhang, Evgeni Tzvetkov, Mark A. Jensen, Timothy B. Niewold, Elise M. N. Ferre, Julie Nardone, Michail S. Lionakis, Jaromir Vlach, Julie DeMartino, Andrew T. Bender
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Autoimmune diseases vary in the magnitude and diversity of autoantibody profiles, and these differences may be a consequence of different types of breaks in tolerance. Here, we compared the disparate autoimmune diseases autoimmune polyendocrinopathy
Externí odkaz:
https://doaj.org/article/e823a778e94642ba916ed495ae37f622
Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity
Autor:
Melinda Przetak, Aditee Deshpande, Simone C. Zimmerli, Noune Tahmassian Morse, Evgeni Tzvetkov, Albertina Pereira, Sonja Reissig, Robert L. Walsky, Shinji L. Okitsu, Philipp Haselmayer, Djordje Musil, Sherer Brian A, Jaromir Vlach, Theresa L. Johnson, Andrew Bender
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 376:397-409
Toll-like receptor (TLR) 7 and TLR8 are transmembrane receptors that recognize single-stranded RNA. Activation of these receptors results in immune cell stimulation and inflammatory cytokine production, which is normally a protective host response. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963e63bf34625b4b6f50f0a262d440b1
https://doi.org/10.1124/jpet.120.000275
https://doi.org/10.1124/jpet.120.000275
Autor:
Shinji L. Okitsu, Timothy B. Niewold, Mark A. Jensen, Yin Wu, Melinda Przetak, Siddha Kasar, Jaromir Vlach, Evgeni Tzvetkov, Albertina Pereira, Andrew Bender
Publikováno v:
ImmunoHorizons. 4:93-107
TLR7 and TLR8 are pattern recognition receptors that reside in the endosome and are activated by ssRNA molecules. TLR7 and TLR8 are normally part of the antiviral defense response, but they have also been implicated as drivers of autoimmune diseases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ebe4936e77adbeff8339be868dcf1e
https://doi.org/10.4049/immunohorizons.2000002
https://doi.org/10.4049/immunohorizons.2000002
Autor:
Shinji L. Okitsu, Sherer Brian A, Philipp Haselmayer, Evgeni Tzvetkov, Andrew Bender, Melinda Przetak, Albertina Pereira, Noune Tahmassian Morse, Jaromir Vlach, Sonja Reissig
Publikováno v:
Oral presentations.
Background TLR 7/8 are transmembrane receptors that recognize single-stranded RNA. In humans, TLR7 is mainly expressed in B cells and plasmacytoid dendritic cells and its activation stimulates antibody production and secretion of cytokines including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08c3e660bb1f65098a930a36dba4857f
https://doi.org/10.1136/lupus-2020-eurolupus.48
https://doi.org/10.1136/lupus-2020-eurolupus.48
Publikováno v:
Lupus Science & Medicine; 2020 Supplement, Vol. 7, pA1-A124, 302p
Autor:
Deshmukh, A., Pereira, A., Geraci, N., Tzvetkov, E., Przetak, M., Catalina, M., Morand, E. F., Bender, A., Vaidyanathan, B.
Publikováno v:
Annals of the Rheumatic Diseases; 2023 Supplement, Vol. 82, p1060-1061, 2p
Autor:
Pericleous, C., Maughan, R., Kabir, L., Dabrowska, A., Paschalaki, K., Carling, D., Randi, A., Arachchillage, D., Mason, J.
Publikováno v:
Annals of the Rheumatic Diseases; 2023 Supplement, Vol. 82, p1061-1062, 2p
Autor:
Rafael Vidal, C., Malvar Fernández, B., Martínez-Ramos, S., Mouriño Rodríguez, C., González, I. Altabás, Floudas, A., Veale, D., Fearon, U., Pego-Reigosa, J. M., García, S.
Publikováno v:
Annals of the Rheumatic Diseases; 2023 Supplement, Vol. 82, p1061-1061, 2/3p
Autor:
Vidal, D., Giuponni, J., Guerini, L., Larroulet, R. C., Galindo, M. S., Farfan, J., Arispe, M., Vilca, I., Franco, L., Gomez, V. Ochoa Y., Marcantoni, M., Deves, V., Pradier, F. Zunino, Rama, M. E., Yesuron, G., Walsh, C. Torres, Pintos, I., Duarte, V., Espada, G.
Publikováno v:
Annals of the Rheumatic Diseases; 2023 Supplement, Vol. 82, p678-678, 2/3p
Publikováno v:
Genomics & Genetics Weekly; 3/3/2023, p1193-1193, 1p