Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Evgeni P Tzvetkov"'
Autor:
James E Norton, Andrew G Lytle, Shixue Shen, Evgeni P Tzvetkov, Corin L Dorfmeier, James P McGettigan
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87098 (2014)
We have previously shown that live-attenuated rabies virus (RABV)-based vaccines infect and directly activate murine and human primary B cells in-vitro, which we propose can be exploited to help develop a single-dose RABV-based vaccine. Here we repor
Externí odkaz:
https://doaj.org/article/13155302d6564e51a863699777ae970f
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 3, p e2129 (2013)
Over two-thirds of the world's population lives in regions where rabies is endemic, resulting in over 15 million people receiving multi-dose post-exposure prophylaxis (PEP) and over 55,000 deaths per year globally. A major goal in rabies virus (RABV)
Externí odkaz:
https://doaj.org/article/c660e49a54cc435490a9ad5b0357a074
Autor:
James P. McGettigan, Andrew G. Lytle, Kishore R. Alugupalli, Evgeni P. Tzvetkov, Joseph R Plummer, Shannon L. Haley
Publikováno v:
Antiviral Research. 144:130-137
There is significant need to develop a single-dose rabies vaccine to replace the current multi-dose rabies vaccine regimen and eliminate the requirement for rabies immune globulin in post-exposure settings. To accomplish this goal, rabies virus (RABV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a23b1857bec6d74b6fdc95798d9ff2d
https://doi.org/10.1016/j.antiviral.2017.06.004
https://doi.org/10.1016/j.antiviral.2017.06.004
Autor:
Jakub Mieczkowski, Yotam Drier, Su Wang, Scott L. Pomeroy, Burak H. Alver, Bradley E. Bernstein, Charles W. M. Roberts, Ryan S. Lee, Shawn M. Gillespie, Peter J. Park, Michael Y. Tolstorukov, Xiaofeng Wang, Tenley C. Archer, Jaclyn A. Biegel, Jeffrey R. Haswell, Evgeni P. Tzvetkov, Emma C. Troisi, Jennifer Wu
Publikováno v:
Nature genetics
SMARCB1 (also known as SNF5, INI1, and BAF47), a core subunit of the SWI/SNF (BAF) chromatin-remodeling complex, is inactivated in nearly all pediatric rhabdoid tumors. These aggressive cancers are among the most genomically stable, suggesting an epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc2433191d995a148f8b4f474e15267
http://europepmc.org/articles/PMC5285474
http://europepmc.org/articles/PMC5285474
Autor:
William H. Hawk, Evgeni P. Tzvetkov, Thomas P. Howard, Jeffrey R. Haswell, Emma C. Troisi, Pilar Ramos, Elaine M. Oberlick, Peter J. Park, Aaron Ross, Charles W. M. Roberts, Su Wang, William C. Hahn, Francisca Vazquez, Bennett K. Wolf, Xiaofeng Wang
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Bromodomain-containing protein 9 (BRD9) is a recently identified subunit of SWI/SNF(BAF) chromatin remodeling complexes, yet its function is poorly understood. Here, using a genome-wide CRISPR-Cas9 screen, we show that BRD9 is a specific vulnerabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dbbb6b953eb21a5ee628eebea57d83f
http://europepmc.org/articles/PMC6479050
http://europepmc.org/articles/PMC6479050
Autor:
James P. McGettigan, Evgeni P. Tzvetkov, Samantha Meuwissen, Shannon L. Haley, Joseph R Plummer
Publikováno v:
Journal of virology. 91(8)
Vaccine-induced B cells differentiate along two pathways. The follicular pathway gives rise to germinal centers (GCs) that can take weeks to fully develop. The extrafollicular pathway gives rise to short-lived plasma cells (PCs) that can rapidly secr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a521168e03a9eede0e4c4507c76df0b6
https://pubmed.ncbi.nlm.nih.gov/28148792
https://pubmed.ncbi.nlm.nih.gov/28148792
Autor:
Xiaofeng Wang, Evgeni P. Tzvetkov, William C. Hahn, William H. Hawk, Thomas P. Howard, Francisca Vazquez, Bennett K. Wolf, Pilar Ramos, Elaine M. Oberlick, Charles W. M. Roberts, Emma C. Troisi, Aaron Ross, Su Wang, Peter J. Park, Jeffrey R. Haswell
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6af777efee91a5fb973f67bb6d02794
http://link.springer.com/article/10.1038/s41467-019-12524-8
http://link.springer.com/article/10.1038/s41467-019-12524-8
Publikováno v:
Journal of Virology. 87:9217-9222
B cells secreting IgG antibodies, but not IgM, are thought to be solely responsible for vaccine-induced protection against rabies virus (RABV) infections in postexposure settings. In this report, we reinvestigated the potential for IgM to mediate pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d15787827a0707215381737271e574
https://doi.org/10.1128/jvi.00995-13
https://doi.org/10.1128/jvi.00995-13
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 7, Iss 3, p e2129 (2013)
PLoS Neglected Tropical Diseases, Vol 7, Iss 3, p e2129 (2013)
Over two-thirds of the world's population lives in regions where rabies is endemic, resulting in over 15 million people receiving multi-dose post-exposure prophylaxis (PEP) and over 55,000 deaths per year globally. A major goal in rabies virus (RABV)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6da1ebddc0283b26d3fa7589b966e169
http://europepmc.org/articles/PMC3597479
http://europepmc.org/articles/PMC3597479
Autor:
Xiaofeng Wang, Su Wang, Emma C. Troisi, Thomas P. Howard, Jeffrey R. Haswell, Bennett K. Wolf, William H. Hawk, Pilar Ramos, Elaine M. Oberlick, Evgeni P. Tzvetkov, Aaron Ross, Francisca Vazquez, William C. Hahn, Peter J. Park, Charles W. M. Roberts
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Mutations of the SWI/SNF chromatin-remodeling complex member SMARCB1 can cause malignant rhaboid tumors. Here the authors report a BRD9-containing SWI/SNF subcomplex that lacks SMARCB1 and its requirement for the survival of rhaboid tumors.
Externí odkaz:
https://doaj.org/article/4b69173f717e4efcb19c2a38dcdb58fd