Výsledky vyhledávání

Identification of a possible proteomic biomarker in Parkinson’s disease: discovery and replication in blood, brain and CSF

Autor: Winchester, L, Barber, I, Lawton, M, Ash, J, Liu, B, Evetts, S, Hopkins-Jones, L, Lewis, S, Bresener, C, Malpartida, AB, Williams, N, Gentlemen, S, Wade-Martins, R, Ryan, B, Nevado-Holgado, A, Hu, M, Ben-Shlomo, Y, Grosset, D, Lovestone, S

Publikováno v: Winchester, L, Barber, I, Lawton, M A, Ash, J, Liu, B, Evetts, S, Hopkins-Jones, L, Lewis, S, Bresner, C, Malpartida, A B, Williams, N, Gentlemen, S, Wade-Martins, R, Ryan, B, Holgado-Nevado, A, Hu, M, Ben-Shlomo, Y, Grosset, D & Lovestone, S 2022, ' Identification of a possible proteomic Biomarker in Parkinson’s Disease : Discovery and Replication in Blood, brain and CSF ', Brain Communications . https://doi.org/10.1093/braincomms/fcac343

Biomarkers to aid diagnosis and delineate progression of Parkinson’s Disease are vital for targeting treatment in the early phases of disease. Here, we aim to discover a multi-protein panel representative of Parkinson’s and make mechanistic infer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::873caa8f82a1bbbf6a8fddd0778fb621
https://doi.org/10.1093/braincomms/fcac343

Zobrazit plný text záznamu

Potential Metabolomic Linkage in Blood between Parkinson's Disease and Traumatic Brain Injury

Autor: Fiandaca, MS, Gross, TJ, Johnson, TM, Hu, MT, Evetts, S, Wade-Martins, R, Merchant-Borna, K, Bazarian, J, Cheema, AK, Mapstone, M, Federoff, HJ

Publikováno v: Fiandaca, MS; Gross, TJ; Johnson, TM; Hu, MT; Evetts, S; Wade-Martins, R; et al.(2018). Potential Metabolomic Linkage in Blood between Parkinson's Disease and Traumatic Brain Injury. METABOLITES, 8(3). doi: 10.3390/metabo8030050. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7x47b9ns

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::ddf892411c85da517ebb4ef50ce67ec4
http://www.escholarship.org/uc/item/7x47b9ns

Zobrazit plný text záznamu

Mitochondrial dysfunction and increased glycolysis in prodromal and early Parkinson's blood cells

Autor: Smith, A, Depp, C, Ryan, B, Johnston, G, Alegre-Abarrategui, J, Evetts, S, Rolinski, M, Baig, F, Ruffmann, C, Simon, A, Hu, M, Wade-Martins, R

Publikováno v: Smith, A M, Depp, C, Ryan, B J, Johnston, G I, Alegre-Abarrategui, J, Evetts, S, Rolinski, M, Baig, F, Ruffmann, C, Simon, A K, Hu, M T M & Wade-Martins, R 2018, ' Mitochondrial dysfunction and increased glycolysis in prodromal and early Parkinson's blood cells ', Movement Disorders, vol. 33, no. 10, pp. 1580-1590 . https://doi.org/10.1002/mds.104

Background: Although primarily a neurodegenerative process, there is increasing awareness of peripheral disease mechanisms in Parkinson's disease. To investigate disease processes in accessible patient cells, we studied peripheral blood mononuclear c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::41fc3c393042b5f4fe011fddbb07ed3d
http://hdl.handle.net/10044/1/66013

Zobrazit plný text záznamu

Whole-exome sequencing of 228 patients with sporadic Parkinson's disease

Autor: Sandor, C, Honti, F, Haerty, W, Szewczyk-Krolikowski, K, Tomlinson, P, Evetts, S, Millin, S, Keane, T, McCarthy, S, Durbin, R, Talbot, K, Hu, M, Webber, C, Ponting, C, Wade-Martins, R

Publikováno v: Sandor, C, Honti, F, Haerty, W, Krolikowski, K, Tomlinson, P, Evetts, S, Millin, S, Keane, T, McCarthy, S, Durbin, R, Talbot, K, Webber, C, Hu, M, Ponting, C & Wade-Martins, R 2017, ' Whole-exome sequencing of 228 patients with sporadic Parkinson's disease ', Scientific Reports . https://doi.org/10.1038/srep41188

Parkinson’s disease (PD) is the most common neurodegenerative movement disorder, affecting 1% of the population over 65 years characterized clinically by both motor and non-motor symptoms accompanied by the preferential loss of dopamine neurons in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::dc060ce7a6bd4a1d506d9a4cef2d07d0
https://orca.cardiff.ac.uk/id/eprint/135795/1/srep41188.pdf

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání