Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Everton Luiz Pompeu Varela"'
Autor:
Heliton Patrick Cordovil Brígido, Everton Luiz Pompeu Varela, Antônio Rafael Quadros Gomes, Jorddy Neves Cruz, Juliana Correa-Barbosa, José Edson de Sousa Siqueira, Cristian Kallahan Silva Chagas, Andrey Moacir do Rosário Marinho, Liliane Almeida Carneiro, Márlia Regina Coelho-Ferreira, Sandro Percário, Maria Fâni Dolabela
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
The lack of vaccines shows the need for alternative leishmaniasis treatments. In vitro study previously demonstrated the leishmanicidal activity of A. nitidum extracts. This study describes for the first time, the antileishmanial activity of A. nitid
Externí odkaz:
https://doaj.org/article/bdf63c1e8d154479b9c190622785d6ed
Autor:
Heliton Patrick Cordovil Brígido, Everton Luiz Pompeu Varela, Antônio Rafael Quadros Gomes, Mirian Letícia Carmo Bastos, Andre de Oliveira Feitosa, Andrey Moacir do Rosário Marinho, Liliane Almeida Carneiro, Márlia Regina Coelho-Ferreira, Maria Fâni Dolabela, Sandro Percário
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract This study investigated the acute and subacute toxicity of the ethanolic extract (EE) and alkaloid fraction (FA) from A. nitidum. The EE was obtained from trunk bark with ethanol, FA was obtained from the fractionation of EE. To test the acu
Externí odkaz:
https://doaj.org/article/c663f7942fe145589bd57c0de26983f8
Autor:
Antônio Rafael Quadros Gomes, Jorddy Neves Cruz, Ana Laura Gadelha Castro, Heliton Patrick Cordovil Brigido, Everton Luiz Pompeu Varela, Valdicley Vieira Vale, Liliane Almeida Carneiro, Gleison Gonçalves Ferreira, Sandro Percario, Maria Fâni Dolabela
Publikováno v:
Molecules, Vol 28, Iss 14, p 5557 (2023)
From Eleutherine plicata, naphthoquinones, isoeleutherine, and eleutherol were isolated, and previous studies have reported the antioxidant activity of these metabolites. The present work evaluated the role of oxidative changes in mice infected with
Externí odkaz:
https://doaj.org/article/f5df926b26904defa91e180bebd66971
Autor:
Danilo Reymão Moreira, Ana Carolina Musa Gonçalves Uberti, Antonio Rafael Quadros Gomes, Michelli Erica Souza Ferreira, Aline da Silva Barbosa, Everton Luiz Pompeu Varela, Maria Fani Dolabela, Sandro Percário
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The present study aimed to evaluate the effects of dexamethasone on the redox status, parasitemia evolution, and survival rate of Plasmodium berghei-infected mice. Two-hundred and twenty-five mice were infected with Plasmodium berghei and su
Externí odkaz:
https://doaj.org/article/6e9c9a22fb8d4bdbb657cdef28d91fec
Autor:
Antonio Rafael Quadros Gomes, Natasha Costa da Rocha Galucio, Kelly Cristina Oliveira de Albuquerque, Heliton Patrick Cordovil Brígido, Everton Luiz Pompeu Varela, Ana Laura Gadelha Castro, Valdicley Vieira Vale, Marcelo Oliveira Bahia, Rommel Mario Rodriguez Burbano, Fábio Alberto de Molfeta, Liliane Almeida Carneiro, Sandro Percario, Maria Fâni Dolabela
Publikováno v:
Toxicology Reports, Vol 8, Iss , Pp 1480-1487 (2021)
Eleutherine plicata has been shown to be a promising medicinal plant, and its activity has been associated with naphthoquinones. The present study aimed at evaluating the cytotoxicity, genotoxicity, and oral toxicity of the ethanol extract (EEEp), di
Externí odkaz:
https://doaj.org/article/b9b57379b9ae405281cf9a6653e7f86f
Autor:
Everton Luiz Pompeu Varela, Antônio Rafael Quadros Gomes, Aline da Silva Barbosa dos Santos, Eliete Pereira de Carvalho, Valdicley Vieira Vale, Sandro Percário
Publikováno v:
Nutrients, Vol 14, Iss 24, p 5303 (2022)
Malaria is a disease that affects thousands of people around the world every year. Its pathogenesis is associated with the production of reactive oxygen and nitrogen species (RONS) and lower levels of micronutrients and antioxidants. Patients under d
Externí odkaz:
https://doaj.org/article/cd2a848d91e444878ee5ef4f9b1b2f6b
Autor:
Leonardo Souza da Costa, Ângelo Antônio Barbosa de Moraes, Jorddy Neves Cruz, Suraj N. Mali, Lorena Queiroz Almeida, Lidiane Diniz do Nascimento, Oberdan Oliveira Ferreira, Everton Luiz Pompeu Varela, Sandro Percário, Mozaniel Santana de Oliveira, Eloisa Helena de Aguiar Andrade
Publikováno v:
Antioxidants, Vol 11, Iss 12, p 2410 (2022)
Croton campinarensis Secco, A. Rosário & PE Berry is an aromatic species recently discovered in the Amazon region. This study first reports the chemical profile, antioxidant capacity, and preliminary toxicity to A. salina Leach of the essential oil
Externí odkaz:
https://doaj.org/article/7717a1fbac5e4f4f835aea5a03ac61c0
Autor:
Kaio Murilo Monteiro Espíndola, Everton Luiz Pompeu Varela, Rosyana de Fátima Vieira de Albuquerque, Rosiane Araújo Figueiredo, Sávio Monteiro dos Santos, Nívea Silva Malcher, Pamela Suelen da S. Seabra, Andréia do Nascimento Fonseca, Karla Marcely de Azevedo Sousa, Susan Beatriz Batista de Oliveira, Agnaldo da Silva Carneiro, Michael D. Coleman, Marta Chagas Monteiro
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 57 (2022)
Dapsone (DDS) therapy can frequently lead to hematological side effects, such as methemoglobinemia and DNA damage. In this study, we aim to evaluate the protective effect of racemic alpha lipoic acid (ALA) and its enantiomers on methemoglobin inducti
Externí odkaz:
https://doaj.org/article/b1188371a583441892373004dec001b6
Autor:
Ângelo Antônio Barbosa de Moraes, Oberdan Oliveira Ferreira, Leonardo Souza da Costa, Lorena Queiroz Almeida, Everton Luiz Pompeu Varela, Márcia Moraes Cascaes, Celeste de Jesus Pereira Franco, Sandro Percário, Lidiane Diniz do Nascimento, Mozaniel Santana de Oliveira, Eloisa Helena de Aguiar Andrade
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 2076 (2022)
The essential oils (EOs) of Myrciaria floribunda (Mflo) and Myrcia sylvatica (Msyl) (Myrtaceae) were obtained by hydrodistillation. The analysis of volatile constituents was performed by GC/MS. Preliminary toxicity was assessed on Artemia salina Leac
Externí odkaz:
https://doaj.org/article/4114a3fc896e49f4a45b21d69d125ef5
Autor:
Vinicius Ruan Neves dos Santos, Deborah Ribeiro Frazão, Railson de Oliveira Ferreira, Paulo Fernando Santos Mendes, Daiane Claydes Baia-da-Silva, Deiweson Souza-Monteiro, Leonardo Oliveira Bittencourt, João Daniel Mendonça de Moura, José Messias Perdigão, Bruno José Brito Teixeira, Everton Luiz Pompeu Varela, Gabriela de Souza Balbinot, Sandro Percário, Herve Rogez, Cassiano Kuchenbecker Rösing, Fabrício Mezzomo Collares, Rafael Rodrigues Lima
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 1902 (2022)
Açaí (Euterpe oleracea Mart.) juice is rich in phenolic compounds with high antioxidant capacity. It has been observed that the use of antioxidants may be an additional strategy to nonsurgical periodontal therapy as well as to prevent alveolar bone
Externí odkaz:
https://doaj.org/article/d549c8b5ab404c338a63a55a68eea6d1